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公开(公告)号：US09044142B2
公开(公告)日：2015-06-02
申请号：US13043120
申请日：2011-03-08
申请人： Christoph Hauger , Guido Hattendorf , Peter Maxwell Delaney , Robert F. Spetzler , Mark C. Preul , Jennifer Eschbacher , Peter Nakaji
发明人： Christoph Hauger , Guido Hattendorf , Peter Maxwell Delaney , Robert F. Spetzler , Mark C. Preul , Jennifer Eschbacher , Peter Nakaji
CPC分类号： A61B5/0068 , A61B1/00188 , A61B1/043 , A61B1/313 , A61B5/4064 , A61B90/20 , G02B21/0052
摘要： A method of detecting a brain tumor includes administering indocyanine green to a living body; exposing brain tissue in the living body; irradiating the exposed brain tissue with excitation light of indocyanine green; obtaining an image based on fluorescence of the excited indocyanine green in the brain tissue, wherein the image is obtained using an endomicroscope; and identifying portions of the brain tissue corresponding to the brain tumor based on the image.
摘要翻译： 检测脑肿瘤的方法包括向活体施用吲哚青绿; 暴露生物体内的脑组织; 用吲哚菁绿的激发光照射暴露的脑组织; 基于脑组织中激发的吲哚菁绿的荧光获得图像，其中使用内窥镜获得图像; 以及基于图像识别与脑肿瘤相对应的脑组织的部分。
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公开(公告)号：US20110280810A1
公开(公告)日：2011-11-17
申请号：US13043120
申请日：2011-03-08
申请人： Christoph Hauger , Guido Hattendorf , Peter Maxwell Delaney , Robert F. Spetzler , Mark C. Preul , Jennifer Eschbacher , Peter Nakaji
发明人： Christoph Hauger , Guido Hattendorf , Peter Maxwell Delaney , Robert F. Spetzler , Mark C. Preul , Jennifer Eschbacher , Peter Nakaji
CPC分类号： A61B5/0068 , A61B1/00188 , A61B1/043 , A61B1/313 , A61B5/4064 , A61B90/20 , G02B21/0052
摘要： A method of detecting a brain tumor includes administering indocyanine green to a living body; exposing brain tissue in the living body; irradiating the exposed brain tissue with excitation light of indocyanine green; obtaining an image based on fluorescence of the excited indocyanine green in the brain tissue, wherein the image is obtained using an endomicroscope; and identifying portions of the brain tissue corresponding to the brain tumor based on the image.
摘要翻译： 检测脑肿瘤的方法包括向活体施用吲哚青绿; 暴露生物体内的脑组织; 用吲哚菁绿的激发光照射暴露的脑组织; 基于脑组织中激发的吲哚菁绿的荧光获得图像，其中使用内窥镜获得图像; 以及基于图像识别与脑肿瘤相对应的脑组织的部分。
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公开(公告)号：US08048407B2
公开(公告)日：2011-11-01
申请号：US10554046
申请日：2004-04-26
申请人： Brent Vernon , Merrill Birdno , Mark C. Preul
发明人： Brent Vernon , Merrill Birdno , Mark C. Preul
IPC分类号： A61K31/74 , A61K49/04 , A61K31/765
CPC分类号： A61K49/0404
摘要： A method and composition for treating arteriovenous malformations (AVMs), or abnormal vasculature in the body are provided. The method comprises introducing into the region of an AVM a composition comprising a nucleophilic component, such as a thiol, and a component containing a conjugated unsaturated bond, such as an acrylate through a catheter, whereby the composition crosslinks within the body to block or occlude the AVM.
摘要翻译： 提供了用于治疗动静脉畸形（AVM）或身体异常脉管系统的方法和组合物。 该方法包括通过导管向AVM的区域中引入包含亲核成分（如硫醇）和含有共轭不饱和键的成分（例如丙烯酸酯）的组合物，由此组合物在体内交联以阻断或封闭 AVM。
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