公开(公告)号：US12125135B2

公开(公告)日：2024-10-22

申请号：US18363320

申请日：2023-08-01

Applicant: Carl Zeiss Meditec AG

Inventor： Christoph Hauger ,  Tilman Schmoll ,  Nancy Hecker-Denschlag ,  Joachim Steffen

IPC: G06T15/08 ,  A61B3/10 ,  A61B5/00 ,  A61B90/00 ,  A61B90/20 ,  G06T15/20 ,  H04N13/117 ,  H04N13/207 ,  H04N13/398

CPC classification number: G06T15/08 ,  A61B5/0066 ,  A61B90/20 ,  G06T15/20 ,  H04N13/117 ,  H04N13/207 ,  H04N13/398 ,  A61B2090/3735 ,  G06T2200/24 ,  G06T2210/62

Abstract: The present invention relates to a system for acquiring and visualizing OCT signals, comprising an OCT system and a display means designed for the time-resolved display of image data. The system further comprises a control unit configured to drive the OCT system to acquire a time-resolved OCT signal of a selected field of view of the sample and to determine a time-resolved OCT image on the basis of the acquired time-resolved OCT signal and a specifiable virtual viewing direction and to display the time-resolved OCT image on the display means. The present invention also relates to a corresponding method for acquiring and visualizing OCT signals.

公开(公告)号：US12053261B2

公开(公告)日：2024-08-06

申请号：US16773400

申请日：2020-01-27

Applicant: CALIBER IMAGING & DIAGNOSTICS, INC.

Inventor： William J. Fox ,  Scott R. Grodevant ,  Christopher C. Distasio

IPC: A61B5/00 ,  A61B90/20 ,  G02B5/30 ,  G02B21/00

CPC classification number: A61B5/0068 ,  A61B5/0062 ,  A61B5/0064 ,  A61B5/445 ,  A61B90/20 ,  G02B5/3083 ,  G02B21/0008 ,  G02B21/0028 ,  G02B21/0048 ,  G02B21/0068 ,  G02B21/0072 ,  G02B21/008

Abstract: A confocal microscope having a scanning head in the form of a hand piece (102) which may be placed at selected locations on the body of a patient. A laser beam is scanned in orthogonal (horizontal and vertical) directions by scanners (128, 130) which drive scan mirrors (128a, 130a), which are closely adjacent to each other. The optics include an objective lens (138) and a single telescope lens (132, 134). The telescope provides sufficient magnification to overfill the entrance pupil of the objective lens (138) over the entire scan angle produced by the scan mirrors (128a, 130a). The telescope images the entrance pupil of the objective in the beam path between the mirrors of the scanners. Scanner (128) represents a pulse driven resonant scanner (7). The pulse duration is controlled to vary the scan angle and obtain dynamic, electronic image zooming without changing the positional relationship of the telescope lenses.

公开(公告)号：US12053244B2

公开(公告)日：2024-08-06

申请号：US17127591

申请日：2020-12-18

Applicant: Alcon Inc.

Inventor： Steven T. Charles

IPC: A61B34/20 ,  A61B90/20 ,  A61F9/007 ,  G06T7/246 ,  A61B17/00 ,  A61B90/00 ,  A61B90/50

CPC classification number: A61B34/20 ,  A61B90/20 ,  A61F9/007 ,  G06T7/246 ,  A61B2017/00216 ,  A61B2017/00221 ,  A61B2034/2048 ,  A61B2034/2057 ,  A61B2034/2072 ,  A61B2090/3979 ,  A61B2090/502 ,  G06T2207/10048 ,  G06T2207/30196 ,  G06T2207/30204

Abstract: The present disclosure provides a head tracking control system including at least one marker positioned on a head of a surgeon. The system further includes an infrared camera including at least two infrared sensors and that detects infrared light reflected off the at least one marker and sends a signal corresponding to the detected light to a processor, and that executes instructions on the processor to detect a movement of the at least one marker. The system also includes an intelligent tracking system that executes instructions on the processor to determine if the detected movement of the at least one marker corresponds to a defined head movement of the surgeon. The system further includes an ophthalmic surgical microscope including the processor. If the detected movement of the at least one marker corresponds to the defined head movement of the surgeon, the processor executes instructions to control the ophthalmic surgical microscope.

公开(公告)号：US20240252276A1

公开(公告)日：2024-08-01

申请号：US18414998

申请日：2024-01-17

Applicant: Carl Zeiss Meditec AG

Inventor： Felicia WALZ ,  Korbinian SAGER ,  Christian LUTZWEILER ,  Lars STOPPE ,  Roland GUCKLER

IPC: A61B90/00 ,  A61B90/20 ,  G06V20/69 ,  H04N5/265

CPC classification number: A61B90/361 ,  A61B90/20 ,  G06V20/695 ,  H04N5/265 ,  A61B2090/364 ,  A61B2090/373

Abstract: The invention relates to a method for providing an image representation by means of a surgical microscope, comprising obtaining or capturing at least one application parameter, capturing a color image representation of a capture region by means of a camera, capturing a fluorescence image representation of the capture region by means of a fluorescence camera, processing the fluorescence image representation by means of a processing device to optimize it for an overlay with the color image representation, wherein a type of processing is defined based on the at least one application parameter, overlaying the color image representation with the processed fluorescence image representation, and providing an image signal that encodes the overlaid image representation. The invention further relates to a surgical microscope.

公开(公告)号：US12002210B2

公开(公告)日：2024-06-04

申请号：US17124729

申请日：2020-12-17

Applicant: JCR Pharmaceuticals Co., Ltd.

Inventor： Masahide Shiotani ,  Junko Otsuki

IPC: G06K9/00 ,  A61B90/00 ,  A61B90/20 ,  G06T7/00

CPC classification number: G06T7/0016 ,  A61B90/20 ,  A61B90/361 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30044

Abstract: Disclosed are a software for analyzing images of a fertilized egg, the software providing a means for executing a process including: (a) a step of measuring the difference in area between the female pronucleus and the male pronucleus from images of a fertilized egg obtained in a period of 1 to 10 hours before the time of occurrence of male and female pronuclear membrane breakdown as a reference; (b) a step of measuring the difference in are between the female pronucleus and the male pronucleus from images of the fertilized egg obtained immediately before the time of occurrence of male and female pronuclear membrane breakdown as the reference; and (c) a step of storing the measured values of the area difference obtained in the step (a) and the area difference obtained in the step (b), to be readable at any time as needed, and an apparatus incorporating this software.

公开(公告)号：US20240173090A1

公开(公告)日：2024-05-30

申请号：US18551753

申请日：2021-12-28

Applicant: SONY GROUP CORPORATION

Inventor： HIROYUKI SUZUKI ,  ATSUSHI MIYAMOTO ,  TOMOYUKI OOTSUKI

IPC: A61B34/37 ,  A61B34/20 ,  A61B90/14 ,  A61B90/20

CPC classification number: A61B34/37 ,  A61B34/20 ,  A61B90/14 ,  A61B90/20 ,  A61B2034/2068

Abstract: Provided is a surgical system that supports a surgical operation using an observation device and a surgical robot.
The surgical system includes: an observation device that observes an operative field; a surgical robot that supports a surgical tool; a fixing portion that fixes a relationship of relative position and posture between the observation device and the surgical robot; and a processing unit that performs processing for coordinate conversion between coordinates on a captured image of the observation device and coordinates of the surgical tool on the basis of the relationship of relative position and posture. The observation device includes a microscope and a pre-lens, and the fixing portion fixes a relationship of relative position and posture of the surgical robot with respect to the pre-lens.

公开(公告)号：US11953669B2

公开(公告)日：2024-04-09

申请号：US17145495

申请日：2021-01-11

Applicant: KARL STORZ SE & Co. KG

Inventor： Jonas Forster ,  Sebastian Barth ,  Andreas Heni ,  Benedikt Köhler ,  Walter Vogel

IPC: G02B21/36 ,  A61B90/00 ,  A61B90/20 ,  G02B21/00 ,  G02B27/64

CPC classification number: G02B21/361 ,  A61B90/20 ,  A61B90/361 ,  G02B21/0012 ,  G02B27/642 ,  G02B21/368

Abstract: An optical observation instrument according to the invention, in particular a surgical microscope or exoscope, comprises an optics unit with an objective arrangement and at least one electronic image recorder, wherein the optics unit has a first stereo channel with a first beam path and a second stereo channel with a second beam path for recording a stereo image of an object field with the at least one electronic image recorder and wherein the first and the second beam path extend through the objective arrangement. The instrument moreover comprises a retaining apparatus, on which the optics unit is mounted so as to be rotatable about a first axis of rotation, the latter at least approximately corresponding to an axis of the objective arrangement, wherein the optical observation instrument has a viewing direction that is angled in relation to the axis of the objective arrangement and comprises a deflection element, arranged on the object-side of the objective arrangement, for deflecting the first and the second beam path into the objective arrangement. The invention further relates to a method for generating a stereo image of an object field.

公开(公告)号：US20240102795A1

公开(公告)日：2024-03-28

申请号：US18505973

申请日：2023-11-09

Applicant: VISIE Inc.

Inventor： Aaron Charles Bernstein ,  Jeffrey A. Levine ,  Patrick C. Edwards

IPC: G01B11/24 ,  A61B1/00 ,  A61B1/06 ,  A61B34/10 ,  A61B34/20 ,  A61B90/00 ,  A61B90/20 ,  A61B90/30 ,  F21V1/08 ,  F21V1/10 ,  F21V7/00 ,  F21V11/12 ,  G06T15/60

CPC classification number: G01B11/2433 ,  A61B1/000095 ,  A61B1/00194 ,  A61B1/0605 ,  A61B34/10 ,  A61B34/20 ,  A61B90/20 ,  A61B90/30 ,  A61B90/37 ,  F21V1/08 ,  F21V1/10 ,  F21V7/005 ,  F21V11/12 ,  G06T15/60 ,  A61B2034/105 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2090/306 ,  A61B2090/365 ,  A61B2090/367 ,  A61B2090/373 ,  A61B2090/374 ,  A61B2090/3762 ,  F21Y2103/00 ,  G06T2215/12

Abstract: Disclosed herein are various embodiments related generally to computer vision, graphics, image scanning, shadow casters, shadow caster scanners, and image processing as well as associated mechanical, electrical and electronic hardware, computer software and systems, and wired and wireless network communications to form at least three-dimensional models or images of objects, scenes, and environments.

公开(公告)号：US20240093289A1

公开(公告)日：2024-03-21

申请号：US18363298

申请日：2023-08-01

Applicant: The General Hospital Corporation

Inventor： Christa Haase ,  Dmitry Richter ,  Charles Lin

IPC: C12Q1/6869 ,  A61B10/02 ,  A61B18/20 ,  A61B90/20

CPC classification number: C12Q1/6869 ,  A61B10/02 ,  A61B18/20 ,  A61B90/20 ,  A61B2018/00565

Abstract: A system and method for image-guided cell isolation from a region of interest of a subject is disclosed. The system and method include imaging the subject using optical microscopy to identify the region of interest in a target anatomy, inserting a micropipette into the region of interest under guidance of the optical microscopy, and aspirating at least one cell of a target population of cells in the region of interest under guidance of the optical microscopy. The method further includes analyzing the at least one cell aspirated from the region of interest.

公开(公告)号：US20240065788A1

公开(公告)日：2024-02-29

申请号：US18495436

申请日：2023-10-26

Applicant: MEDICAL MICROINSTRUMENTS, INC.

Inventor： Massimiliano SIMI ,  Giuseppe Maria PRISCO

IPC: A61B34/37 ,  A61B1/313 ,  A61B10/04 ,  A61B17/00 ,  A61B17/062 ,  A61B34/00 ,  A61B34/30 ,  A61B34/35 ,  A61B90/00 ,  A61B90/20 ,  A61B90/25 ,  B25J3/04 ,  B25J9/10 ,  B25J9/16 ,  B25J15/00 ,  G05B19/402

CPC classification number: A61B34/37 ,  A61B1/3132 ,  A61B10/04 ,  A61B17/00234 ,  A61B17/062 ,  A61B34/30 ,  A61B34/35 ,  A61B34/71 ,  A61B34/72 ,  A61B90/20 ,  A61B90/25 ,  A61B90/361 ,  B25J3/04 ,  B25J9/1015 ,  B25J9/1669 ,  B25J15/0052 ,  G05B19/402 ,  A61B2034/2048 ,  A61B2034/301 ,  A61B2034/715 ,  A61B2090/061 ,  A61B2090/064 ,  G05B2219/45117

Abstract: A robotic surgical assembly (100) includes a support (104), one macro-positioning arm (30), connected to the support (104) and having a plurality of degrees of freedom. The macro-positioning arm (30) includes a support member (38), at least two micro-positioning devices (41, 141, 241, 341), each having a plurality of motorized degrees of freedom, connected in cascade to the support member (38) of the macro-positioning arm (30), and at least two medical instruments (60, 160, 260, 360). Each instrument is connected in cascade to each of the micro-positioning device and includes a jointed device (70, 170, 270) having a plurality of motorized degrees of freedom including a plurality of rotational joints. Each of the at least two medical instruments (60, 160, 260, 360) has a shaft (65), suitable for distancing the jointed device from the micro-positioning devices by a predetermined distance in a shaft direction (X-X).