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公开(公告)号：US09517121B2
公开(公告)日：2016-12-13
申请号：US12482978
申请日：2009-06-11
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A graft includes a flexible, resilient, generally tubular external support and a blood vessel segment, carried within and having an ablumenal surface in contact with and supported by the tubular support, the graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 移植物包括柔性的，弹性的，大体上管状的外部支撑物和血管段，其承载在并具有与管状支撑件接触并由其支撑的缩小表面，所述移植物能够以模拟径向顺应性的方式弹性径向膨胀 动脉的性质。
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公开(公告)号：US08382814B2
公开(公告)日：2013-02-26
申请号：US13209517
申请日：2011-08-15
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F Wolf , Paul Human
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F Wolf , Paul Human
IPC: A61F2/06
CPC classification number: A61B17/11 , A61B5/1076 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/95 , A61F2240/002
Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.
Abstract translation: 提供支架和使用支架的方法。 本发明的支架为设置在其内的血管段提供外部支撑结构，其中支架能够以模仿动脉的顺应性的方式弹性径向扩张。 支架可以由形成的针织或编织网形成，以便提供所需的顺应性。 提供具有支架和设置在其内的静脉段的静脉移植物，其中移植物能够模拟动脉的顺应性。 提供了选择小型化支架的方法和使用本发明的支架在缩小和平滑方面的方法。 提供了用包括本发明的支架的静脉移植物代替动脉的一部分的方法。 提供了使用本发明的支架在静脉移植物中减少植入静脉段内膜增生的方法。
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公开(公告)号：US20050131520A1
公开(公告)日：2005-06-16
申请号：US10987313
申请日：2004-11-12
Applicant: Peter Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael Wolf
Inventor： Peter Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael Wolf
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a blood vessel segment, e.g., a vein segment, carried within and having an ablumenal surface in contact with and supported by the tubular support, the graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 用于替换动脉的一部分的移植物和制造移植物的方法。 移植物包括柔性的，弹性的，大体上管状的外部支撑件和血管段，例如静脉段，其承载在并具有与管状支撑件接触并由其支撑的腹膜表面，所述移植物能够弹性径向膨胀 模拟动脉的径向顺应性的方式。
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公开(公告)号：US20120116495A1
公开(公告)日：2012-05-10
申请号：US13351591
申请日：2012-01-17
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
IPC: A61F2/06
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 用于替换动脉的一部分的静脉移植物和制造移植物的方法。 移植物包括柔性的，弹性的，大体上管状的外部支撑件和承载在管状支撑件内并具有与管状支撑件接触并由其支撑的缩小表面的静脉段，静脉移植物能够以模拟径向顺应性的方式弹性径向膨胀 的动脉。
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公开(公告)号：US08172746B2
公开(公告)日：2012-05-08
申请号：US12388702
申请日：2009-02-19
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Narenk Douk , Michael F. Wolf
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Narenk Douk , Michael F. Wolf
IPC: A61F2/04
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 用于替换动脉的一部分的静脉移植物和制造移植物的方法。 移植物包括柔性的，弹性的，大体上管状的外部支撑件和承载在管状支撑件内并具有与管状支撑件接触并由其支撑的缩小表面的静脉段，静脉移植物能够以模拟径向顺应性的方式弹性径向膨胀 的动脉。
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Patent Agency Ranking
公开(公告)号：US07998188B2
公开(公告)日：2011-08-16
申请号：US11797648
申请日：2007-05-04
Applicant: Peter Paul Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf , Paul Human
Inventor： Peter Paul Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf , Paul Human
IPC: A61F2/06
CPC classification number: A61B17/11 , A61B5/1076 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/95 , A61F2240/002
Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.
Abstract translation: 提供支架和使用支架的方法。 本发明的支架为设置在其内的血管段提供外部支撑结构，其中支架能够以模仿动脉的顺应性的方式弹性径向扩张。 支架可以由形成的针织或编织网形成，以便提供所需的顺应性。 提供具有支架和设置在其内的静脉段的静脉移植物，其中移植物能够模拟动脉的顺应性。 提供了选择小型化支架的方法和使用本发明的支架在缩小和平滑方面的方法。 提供了用包括本发明的支架的静脉移植物代替动脉的一部分的方法。 提供了使用本发明的支架在静脉移植物中减少植入静脉段内膜增生的方法。
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公开(公告)号：US08057537B2
公开(公告)日：2011-11-15
申请号：US10834360
申请日：2004-04-28
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
IPC: A61F2/90
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 用于替换动脉的一部分的静脉移植物和制造移植物的方法。 移植物包括柔性的，弹性的，大体上管状的外部支撑件和承载在管状支撑件内并具有与管状支撑件接触并由其支撑的缩小表面的静脉段，静脉移植物能够以模拟径向顺应性的方式弹性径向膨胀 的动脉。
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公开(公告)号：US20090306764A1
公开(公告)日：2009-12-10
申请号：US12482978
申请日：2009-06-11
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael F. Wolf
IPC: A61F2/06
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A graft includes a flexible, resilient, generally tubular external support and a blood vessel segment, carried within and having an ablumenal surface in contact with and supported by the tubular support, the graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 移植物包括柔性的，弹性的，大体上管状的外部支撑物和血管段，其承载在并具有与管状支撑件接触并由其支撑的缩小表面，所述移植物能够以模拟径向顺应性的方式弹性径向膨胀 动脉的性质。
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公开(公告)号：US20090163987A1
公开(公告)日：2009-06-25
申请号：US12388702
申请日：2009-02-19
Applicant: Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Narenk Douk , Michael F. Wolf
Inventor： Peter P. Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Narenk Douk , Michael F. Wolf
CPC classification number: A61F2/06 , A61F2/90 , A61L27/14 , A61L27/3625
Abstract: A venous graft for replacement of a section of an artery and methods of making the graft. The graft comprises a flexible, resilient, generally tubular external support and a vein segment carried within and having an ablumenal surface in contact with and supported by the tubular support, the venous graft being capable of resilient radial expansion in a manner mimicking the radial compliance properties of an artery.
Abstract translation: 用于替换动脉的一部分的静脉移植物和制造移植物的方法。 移植物包括柔性的，弹性的，大体上管状的外部支撑件和承载在管状支撑件内并具有与管状支撑件接触并由其支撑的缩小表面的静脉段，静脉移植物能够以模拟径向顺应性的方式弹性径向膨胀 的动脉。
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公开(公告)号：US20070293932A1
公开(公告)日：2007-12-20
申请号：US11797648
申请日：2007-05-04
Applicant: Peter Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael Wolf , Paul Human
Inventor： Peter Zilla , Nasser Rafiee , Deon Bezuidenhout , Thomas Franz , Mark Yeoman , Hellmut Bowles , Nareak Douk , Michael Wolf , Paul Human
CPC classification number: A61B17/11 , A61B5/1076 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/856 , A61F2/90 , A61F2/95 , A61F2240/002
Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.
Abstract translation: 提供支架和使用支架的方法。 本发明的支架为设置在其内的血管段提供外部支撑结构，其中支架能够以模仿动脉的顺应性的方式弹性径向扩张。 支架可以由形成的针织或编织网形成，以便提供所需的顺应性。 提供具有支架和设置在其内的静脉段的静脉移植物，其中移植物能够模拟动脉的顺应性。 提供了选择小型化支架的方法和使用本发明的支架在缩小和平滑方面的方法。 提供了用包括本发明的支架的静脉移植物代替动脉的一部分的方法。 提供了使用本发明的支架在静脉移植物中减少植入静脉段内膜增生的方法。
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