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公开(公告)号：US20120238799A1
公开(公告)日：2012-09-20
申请号：US13462931
申请日：2012-05-03
申请人： Geoffrey R. BALL , Peter LAMPACHER , Bernhard JAMNIG , Martin ZIMMERLING , Gunther WEIDENHOLZER , Markus NAGL , Wolfgang AMRHEIN
发明人： Geoffrey R. BALL , Peter LAMPACHER , Bernhard JAMNIG , Martin ZIMMERLING , Gunther WEIDENHOLZER , Markus NAGL , Wolfgang AMRHEIN
CPC分类号： A61N1/08 , A61N1/36036 , A61N1/3718 , A61N1/375
摘要： A magnet arrangement is described for use in implantable devices. An implantable housing contains a portion of an implantable electronic system. An implant magnet arrangement within the housing has adjacent magnetic sections that lie substantially in a common plane and include an inner center disc having an inner magnetic orientation in an inner magnetic direction, and an outer radial ring having an outer magnetic orientation in an outer magnetic direction opposite to the inner magnetic direction.
摘要翻译： 描述了用于可植入装置的磁体布置。 可植入的壳体包含可植入电子系统的一部分。 壳体内的植入物磁体布置具有基本上位于公共平面中的相邻的磁性部分，并且包括在内部磁方向上具有内部磁性取向的内部中心盘，以及在外部磁方向上具有外部磁性取向的外部径向环 与内磁方向相反。
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2.发明申请Compositions Comprising N-Halogenated or N,N-Dihalogenated Amine for Treatment and Prophylaxis of Bronchopulmonary Infections 审中-公开包含N-卤代或N，N-二卤代胺用于治疗和预防支气管肺感染的组合物公开(公告)号：US20110151025A1
公开(公告)日：2011-06-23
申请号：US12936508
申请日：2009-04-10
申请人： Waldemar Gottardi , Markus Nagl , Ramin Najafi , Lu Wang , Rakesh K. Jain , Timothy Shiau , Eddy Low , Charles Francavilla
发明人： Waldemar Gottardi , Markus Nagl , Ramin Najafi , Lu Wang , Rakesh K. Jain , Timothy Shiau , Eddy Low , Charles Francavilla
IPC分类号： A61K33/02 , C07C309/14 , A61K31/185 , A61P11/00 , A61P31/00
CPC分类号： A61K31/185 , A61K31/14 , A61K31/198 , A61K31/205 , A61K31/452 , A61K31/662 , A61K31/69 , A61K33/02
摘要： Disclosed herein are methods and compositions for the treatment or prophylaxis, in a mammal, of bronchopulmonary infections, obstructive pulmonary disease, cystic fibrosis, and ventilator-associated infections. The methods and compositions include a therapeutically effective amount of one or more N-halogenated or N,N-dihalogenated amines, and their analogues, derivatives, or pharmaceutically acceptable salts and esters.
摘要翻译： 本文公开了用于在哺乳动物中治疗或预防支气管肺感染，阻塞性肺病，囊性纤维化和呼吸机相关感染的方法和组合物。 所述方法和组合物包括治疗有效量的一种或多种N-卤化或N，N-二卤代胺及其类似物，衍生物或药学上可接受的盐和酯。
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公开(公告)号：US20090182055A1
公开(公告)日：2009-07-16
申请号：US11866924
申请日：2007-10-03
申请人： Waldemar Gottardi , Markus NAGL , Andreas NEHER
发明人： Waldemar Gottardi , Markus NAGL , Andreas NEHER
IPC分类号： A61K31/185 , A61P17/00 , A61P31/10 , A61P15/00 , A61P1/00
CPC分类号： A61K31/185
摘要： A fungicidal agent for treating infectious diseases caused by fungi contains N-chlorotaurine or one of its salts in aqueous solution, optionally with customary pharmaceutical additives.
摘要翻译： 用于治疗由真菌引起的感染性疾病的杀真菌剂含有N-氯代牛磺酸或其水溶液中的一种盐，任选地含有常规的药物添加剂。
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4.发明申请公开(公告)号：US20220273594A1
公开(公告)日：2022-09-01
申请号：US17683197
申请日：2022-02-28
申请人： Markus Nagl
发明人： Markus Nagl
IPC分类号： A61K31/185 , A61P31/14 , A61K9/00 , A61K9/08
摘要： Composition and methods for treatment or prevention of a respiratory infection in a mammal, including a viral infection, like a coronavirus such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), or variants thereof. The compositions and methods include a therapeutically effective amount of about a 1% solution of N-chlorotaurine in water. The methods include administering N-chlorotaurine by nasal spray to the nostrils, by oral spray to the throat, and by nebulizer to the lungs.
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公开(公告)号：US20120172659A1
公开(公告)日：2012-07-05
申请号：US13419552
申请日：2012-03-14
申请人： Geoffrey R. Ball , Peter Lampacher , Bernhard Jamnig , Martin Zimmerling , Gunther Weidenholzer , Markus Nagl , Wolfgang Amrhein
发明人： Geoffrey R. Ball , Peter Lampacher , Bernhard Jamnig , Martin Zimmerling , Gunther Weidenholzer , Markus Nagl , Wolfgang Amrhein
CPC分类号： A61N1/08 , A61N1/36036 , A61N1/3718 , A61N1/375
摘要： A magnet arrangement is described for use with hearing implant systems. An external device for use with an implant system has an external device housing that contains external elements of a hearing implant system. A cylindrical external magnet arrangement within the housing has multiple magnetic sections lying in a common plane, including an inner center disc having an inner magnetic orientation in an inner magnetic direction, and an outer radial ring having an outer magnetic orientation in an outer magnetic direction opposite to the inner magnetic direction.
摘要翻译： 描述了用于听力植入系统的磁体布置。 用于植入系统的外部装置具有包含听力植入系统的外部元件的外部装置壳体。 壳体内的圆柱形外部磁体布置具有位于公共平面中的多个磁性部分，包括在内部磁性方向上具有内部磁性取向的内部中心盘，以及外部磁性定向在外部磁方向相反的外部磁性方向 到内磁方向。
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公开(公告)号：US20110022120A1
公开(公告)日：2011-01-27
申请号：US12839887
申请日：2010-07-20
申请人： Geoffrey R. Ball , Peter Lampacher , Bernhard Jamnig , Martin Zimmerling , Gunrher Weidenholzer , Markus Nagl , Wolfgang Amrhein
发明人： Geoffrey R. Ball , Peter Lampacher , Bernhard Jamnig , Martin Zimmerling , Gunrher Weidenholzer , Markus Nagl , Wolfgang Amrhein
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61N1/36036 , A61N1/3718 , A61N1/375
摘要： A magnet arrangement is described for use in implantable devices. An implantable housing contains a portion of an implantable electronic system. A cylindrical implant magnet arrangement within the housing includes multiple adjacent magnetic sections wherein at least two of the magnetic sections have opposing magnetic orientations in opposite magnetic directions. There may also be a similar external housing having a corresponding magnet arrangement.
摘要翻译： 描述了用于可植入装置的磁体布置。 可植入的壳体包含可植入电子系统的一部分。 壳体内的圆柱形植入物磁体布置包括多个相邻的磁性部分，其中至少两个磁性部分在相反磁性方向上具有相反的磁性取向。 还可以存在具有相应磁体布置的类似的外壳。
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公开(公告)号：US20090029956A1
公开(公告)日：2009-01-29
申请号：US11795220
申请日：2006-01-12
IPC分类号： A61K31/573 , A61P29/00
CPC分类号： A61K31/185 , A61K31/573 , A61K2300/00
摘要： A substance mixture comprising at least one glucocorticoid and at least one N-chloro compound and/or at least one O-chloro compound as well as a medicament containing such a substance mixture as well as the use and manufacture of such a medicament for the topical treatment of inflammations.
摘要翻译： 一种包含至少一种糖皮质激素和至少一种N-氯化合物和/或至少一种O-氯化合物的物质混合物以及含有这种物质混合物的药物，以及这种用于局部 治疗炎症。
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公开(公告)号：US20080207750A1
公开(公告)日：2008-08-28
申请号：US11912368
申请日：2003-12-08
申请人： Waldemar Gottardi , Andreas Neher , Markus Nagl
发明人： Waldemar Gottardi , Andreas Neher , Markus Nagl
IPC分类号： A61K31/255 , A61P17/02
CPC分类号： A61K31/185 , A61K9/0012 , A61K31/13
摘要： A pharmaceutical composition containing N-chlorotaurine is administered to a mammal to treat oozing tissue deficiencies.
摘要翻译： 向哺乳动物施用含有N-氯牛磺酸的药物组合物以治疗渗出性组织缺陷。
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9.发明申请AQUEOUS SOLUTIONS CONTAINING CHLORAMINE WHICH ARE FREE FROM DI-AND TRICHLOROAMINE, AS WELL AS FROM AMMONIA 审中-公开含有氯仿和氯三聚氰胺的水溶液，如阿莫尼亚一样公开(公告)号：US20080269338A1
公开(公告)日：2008-10-30
申请号：US11742303
申请日：2007-04-30
申请人： Waldemar Gottardi , Barbara Teuchner , Markus Nagl
发明人： Waldemar Gottardi , Barbara Teuchner , Markus Nagl
IPC分类号： A61K31/185 , A61P29/00 , A61P31/04
CPC分类号： A61K31/185 , A61K9/08
摘要： The combination of N-chlorotaurine, preferably in the form of sodium salt, and ammonium chloride in aqueous solution absent a buffer is a powerful antiseptic preparation sufficiently stable for use in topical treatment of infections, inflammation and oozing tissue deficiencies. The outstanding microbicidal properties of the preparation are founded in the formation of monochloramine, which is distinguished by the absence, or substantial absence, of dichloramine and trichloramine.
摘要翻译： 非氯代牛磺酸，优选钠盐形式的氯化铵和不含缓冲液的水溶液中的氯化铵的组合是强效的防腐制剂，足以稳定地用于局部治疗感染，炎症和渗出组织缺陷。 制备的突出的杀微生物性质建立在一氯胺的形成中，其通过不存在或基本上不存在二氯胺和三氯胺来区分。
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公开(公告)号：US20070010582A1
公开(公告)日：2007-01-11
申请号：US11147008
申请日：2005-06-06
申请人： Waldemar Gottardi , Andreas Neher , Markus Nagl
发明人： Waldemar Gottardi , Andreas Neher , Markus Nagl
IPC分类号： A61K31/185
CPC分类号： A61K31/185
摘要： A pharmaceutical composition containing N-chlorotaurine is administered to a mammal to treat oozing tissue deficiencies.
摘要翻译： 向哺乳动物施用含有N-氯牛磺酸的药物组合物以治疗渗出性组织缺陷。
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