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1.发明申请INTERACTION CONTROL OF CATIONIC BIOCIDES USING LABILE ANIONIC POLYELECTROLYTES 有权使用可溶性阴离子聚电解质的阳离子生物的相互作用控制公开(公告)号：US20090253800A1
公开(公告)日：2009-10-08
申请号：US12410513
申请日：2009-03-25
CPC分类号： A61L12/143 , A61L12/14 , A61L12/145
摘要： Methods of inhibiting the uptake of cationic biocides into medical devices such as contact lenses and implants are described. Methods of stabilizing emulsions containing cationic biocides are also described. In particular, the present invention provides for the use of polymers acting as labile anionic polyelectrolytes to reversibly bind cationic biocides. The reversible binding can reduce the deleterious effects of cationic biocides while maintaining biocidal activity. Preferred polymers include galactomannan and polyvinyl alcohol.
摘要翻译： 描述了抑制阳离子杀生物剂吸收到医疗装置如隐形眼镜和植入物中的方法。 还描述了稳定含有阳离子杀生物剂的乳液的方法。 特别地，本发明提供了用作不稳定阴离子聚电解质的聚合物可逆地结合阳离子杀生物剂的用途。 可逆结合可以降低阳离子杀生物剂的有害作用，同时保持杀生物活性。 优选的聚合物包括半乳甘露聚糖和聚乙烯醇。
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2.发明授权Interaction control of cationic biocides using labile anionic polyelectrolytes 有权使用不稳定阴离子聚电解质的阳离子杀生物剂的相互作用控制公开(公告)号：US09040510B2
公开(公告)日：2015-05-26
申请号：US12410513
申请日：2009-03-25
IPC分类号： A61L12/14
CPC分类号： A61L12/143 , A61L12/14 , A61L12/145
摘要： Methods of inhibiting the uptake of cationic biocides into medical devices such as contact lenses and implants are described. Methods of stabilizing emulsions containing cationic biocides are also described. In particular, the present invention provides for the use of polymers acting as labile anionic polyelectrolytes to reversibly bind cationic biocides. The reversible binding can reduce the deleterious effects of cationic biocides while maintaining biocidal activity. Preferred polymers include galactomannan and polyvinyl alcohol.
摘要翻译： 描述了抑制阳离子杀生物剂吸收到医疗装置如隐形眼镜和植入物中的方法。 还描述了稳定含有阳离子杀生物剂的乳液的方法。 特别地，本发明提供了用作不稳定阴离子聚电解质的聚合物可逆地结合阳离子杀生物剂的用途。 可逆结合可以降低阳离子杀生物剂的有害作用，同时保持杀生物活性。 优选的聚合物包括半乳甘露聚糖和聚乙烯醇。
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