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公开(公告)号：US20120276531A1
公开(公告)日：2012-11-01
申请号：US13415508
申请日：2012-03-08
申请人： Toshiyuki Saito , Yoji Mikami , Masahiro Kinugasa , Kazuya Mori , Michiyo Sugimoto , Koji Uchida
发明人： Toshiyuki Saito , Yoji Mikami , Masahiro Kinugasa , Kazuya Mori , Michiyo Sugimoto , Koji Uchida
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： To provide a novel method for determining the risk of lymph node metastasis of breast cancer uses as an index the difference in the expression levels of marker genes in at least one material selected from the group consisting of a breast tissue and a breast cell of a patient. The method includes measuring an expression level of a marker gene in at least one material selected from the group consisting of a breast tissue and a breast cell of a patient with breast cancer, and determining the risk of lymph node metastasis of breast cancer in the patient using the expression level of the marker gene as an index.
摘要翻译： 提供一种用于确定乳腺癌用途的淋巴结转移的风险的新方法作为指标，其选自由患者的乳房组织和乳腺细胞组成的组中的至少一种材料中的标记基因的表达水平的差异 。 该方法包括测量在选自乳腺组织和乳腺癌患者的乳腺细胞的至少一种材料中的标记基因的表达水平，并确定患者中乳腺癌淋巴结转移的风险 使用标记基因的表达水平作为指标。
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公开(公告)号：US07598038B2
公开(公告)日：2009-10-06
申请号：US11662781
申请日：2005-09-15
CPC分类号： C12Q1/6895 , C12Q2600/158
摘要： The invention provides a means for estimating the end use qualities of wheat flour that will be obtained in the future from the harvested wheat at an early stage before maturation of the wheat seeds. The invention relates to a method for estimating the end use qualities of a matured wheat seed, comprising measuring the expression level of at least 1 gene selected from genes, each of which is defined by any one of the nucleotide sequences of SEQ ID NOS: 1 to 121 in immature wheat.
摘要翻译： 本发明提供了一种在小麦种子成熟前的早期阶段从收获的小麦获得的小麦面粉的最终使用质量的估算方法。 本发明涉及一种用于估计成熟小麦种子的最终用途品质的方法，包括测量选自基因中的至少1个基因的表达水平，每个基因由SEQ ID NO：1的任一核苷酸序列 到未成熟小麦的121只。
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公开(公告)号：US20090011423A1
公开(公告)日：2009-01-08
申请号：US12183610
申请日：2008-07-31
申请人： Toshiyuki Saito , Yoji Mikami , Masahiro Kinugasa , Kazuya Mori , Michiyo Sugimoto , Koji Uchida
发明人： Toshiyuki Saito , Yoji Mikami , Masahiro Kinugasa , Kazuya Mori , Michiyo Sugimoto , Koji Uchida
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： To provide a novel method for determining the risk of lymph node metastasis of breast cancer uses as an index the difference in the expression levels of marker genes between metastatic breast cancer tissue (or cell) and non-metastatic breast cancer tissue (or cell). The method involves (1) measuring the expression level of a gene having a base sequence in human metastatic breast cancer tissue (or cell), (2) measuring the expression level of the same gene in human non-metastatic breast cancer tissue (or cell), and (3) comparing the expression level of (1) with the expression level of (2) and determine the risk of lymph node metastasis of breast cancer based on the difference between the expression levels.
摘要翻译： 提供一种确定乳腺癌淋巴结转移风险的新方法作为转移性乳腺癌组织（或细胞）与非转移性乳腺癌组织（或细胞）之间标记基因表达水平差异的指标。 该方法包括（1）测量人转移性乳腺癌组织（或细胞）中具有碱基序列的基因的表达水平，（2）测量人非转移性乳腺癌组织（或细胞）中相同基因的表达水平 ）和（3）比较（1）的表达水平与（2）的表达水平，并根据表达水平之间的差异确定乳腺癌淋巴结转移的风险。
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公开(公告)号：US20080213758A1
公开(公告)日：2008-09-04
申请号：US11662781
申请日：2005-09-15
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6895 , C12Q2600/158
摘要： The invention provides a means for estimating the end use qualities of wheat flour that will be obtained in the future from the harvested wheat at an early stage before maturation of the wheat seeds. The invention relates to a method for estimating the end use qualities of a matured wheat seed, comprising measuring the expression level of at least 1 gene selected from genes, each of which is defined by any one of the nucleotide sequences of SEQ ID NOS: 1 to 121 in immature wheat.
摘要翻译： 本发明提供了一种在小麦种子成熟前的早期阶段从收获的小麦获得的小麦面粉的最终使用质量的估算方法。 本发明涉及一种用于估计成熟小麦种子的最终用途品质的方法，包括测量选自基因中的至少1个基因的表达水平，每个基因由SEQ ID NO：1的任一核苷酸序列 到未成熟小麦的121只。
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公开(公告)号：US4646044A
公开(公告)日：1987-02-24
申请号：US712484
申请日：1985-03-18
申请人： Kazuo Kuno , Masahiro Kinugasa
发明人： Kazuo Kuno , Masahiro Kinugasa
CPC分类号： H01F6/06 , Y10S505/879 , Y10T29/49071
摘要： A large diameter, high current capacity, superconductive solenoid coil is formed by winding a conductor around a cylindrical mandrel 2, and then encasing the outer surface of the coil 1 with a support cylinder comprising an assembly of cylinder sectors 11 rigidly joined together along axial seam lines. The joining of the sectors may be implemented by welding, and heat shielding strips 13 may be disposed in recesses 15 in the sectors to prevent thermal damage to the coil insulation 14 during the welding. The support cylinder serves to absorb heat generated during the operation of the coil, and to withstand the outwardly directed electromagnetic forces developed. The mandrel is removed after the cylinder sectors are joined.
摘要翻译： 通过将导体围绕圆柱形心轴2缠绕而形成大直径，高电流容量的超导电磁线圈，然后用包括沿着轴向接缝刚性地连接在一起的气缸扇区11的组件的支撑圆筒包围线圈1的外表面 线条。 扇区的接合可以通过焊接实现，并且热屏蔽带13可以设置在扇区中的凹部15中，以防止在焊接期间对线圈绝缘体14的热损伤。 支撑筒用于吸收在线圈操作期间产生的热量并且承受所产生的向外导向的电磁力。 在圆柱体部分连接之后，心轴被移除。
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公开(公告)号：US20090275045A1
公开(公告)日：2009-11-05
申请号：US12502718
申请日：2009-07-14
申请人： Masahiro Kinugasa , Michiyo Sugimoto , Koji Uchida
发明人： Masahiro Kinugasa , Michiyo Sugimoto , Koji Uchida
IPC分类号： C12Q1/68
CPC分类号： G01N33/57415
摘要： The present invention provides a novel method for detecting mammary cancer cells which uses, as an index, an expression level of a specific gene in human mammary cancer tissue (or cells). The method is characterized by including (1) measuring an expression level of a gene having a specific nucleotide sequence in human mammary cancer tissue (or cells), (2) measuring an expression level of the gene in human normal mammary gland tissue (or cells), and (3) detecting mammary cancer cells on the basis of the difference between measurement values obtained in (1) and (2).
摘要翻译： 本发明提供了一种用于检测乳腺癌细胞的新方法，其以人乳腺癌组织（或细胞）中特异性基因的表达水平作为指标。 该方法的特征在于：（1）测定人乳腺癌组织（或细胞）中具有特定碱基序列的基因的表达水平，（2）测定人正常乳腺组织（或细胞）中基因的表达水平 ），（3）基于（1）和（2）中得到的测定值的差异检测乳腺癌细胞。
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