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    APPARATUS AND METHOD FOR MULTIPLE REACTIONS IN SMALL VOLUMES
    1.
    发明申请
    APPARATUS AND METHOD FOR MULTIPLE REACTIONS IN SMALL VOLUMES 审中-公开
    小容量多种反应的装置和方法

    公开(公告)号：US20130123139A1

    公开(公告)日：2013-05-16

    申请号：US13811638

    申请日：2011-07-25

    申请人： Namyong Kim ,  Siah Chong Cheong ,  Melvin Han Wen Lye ,  Mark Siew Peng Phong ,  Li Li ,  Teow Soon Seah

    发明人： Namyong Kim ,  Siah Chong Cheong ,  Melvin Han Wen Lye ,  Mark Siew Peng Phong ,  Li Li ,  Teow Soon Seah

    IPC分类号： B01L3/00

    CPC分类号： B01L3/5085 ,  B01L3/50853 ,  B01L3/50855 ,  B01L2200/0689 ,  B01L2300/0618 ,  B01L2300/0829 ,  C12M23/12 ,  C12M23/34

    摘要： In some embodiments, the invention relates to a removable grid insertable into an apparatus comprising a plate comprising a number of elements having a first surface energy arranged in an array with an overlay having a second surface energy and a wall circumferential to the plate, said grid comprising dividers enclosing a number of through-holes, said through-holes spaced in the grid to allow alignment of the through- holes of the grid over the elements in the plate when said grid is inserted into the apparatus, wherein said dividers of the grid inserted into the apparatus form sides of wells bottomed by the plate and at least one element on said plate. In other embodiments, the invention also relates to an apparatus comprising: a plate comprising a number of elements, said elements each having an identical diameter and having a first surface energy, said elements arranged in an array in an overlay having a second surface energy, and a wall circumferential to the plate, wherein said overlay is a height over the elements of between about 5% and 100% of the diameter of the elements. In yet addition embodiments, the invention relates to methods for using the apparatuses described herein to perform multiple reactions in small volumes.

    摘要翻译： 在一些实施例中，本发明涉及一种可插入到装置中的可拆卸格栅，该装置包括板，该板包括多个元件，该元件具有排列成阵列的第一表面能，其中覆盖层具有第二表面能和围绕该板的壁， 包括围绕多个通孔的分隔件，所述通孔在格栅中间隔开，以允许当所述格栅插入设备中时格栅的通孔在板上的元件上对准，其中所述网格分隔器 插入到装置中形成由板底部的孔的侧面和所述板上的至少一个元件。 在其他实施例中，本发明还涉及一种装置，包括：板，其包括多个元件，所述元件各自具有相同的直径并且具有第一表面能，所述元件排列成具有第二表面能的覆盖层， 以及围绕板的圆周的壁，其中所述覆盖层是元件的直径的约5％至100％之间的高度。 在另外的实施方案中，本发明涉及使用本文所述的装置以小体积进行多次反应的方法。