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    System and Method for Monitoring Level of Dexmedatomidine-Induced Sedation
    1.
    发明申请
    System and Method for Monitoring Level of Dexmedatomidine-Induced Sedation 审中-公开
    Dexmedatomidine诱导镇静水平的系统和方法

    公开(公告)号：US20140323898A1

    公开(公告)日：2014-10-30

    申请号：US14261188

    申请日：2014-04-24

    申请人： Patrick L. Purdon ,  Oluwaseun Johnson-Akeju ,  Emery N. Brown ,  Michael J. Prerau

    发明人： Patrick L. Purdon ,  Oluwaseun Johnson-Akeju ,  Emery N. Brown ,  Michael J. Prerau

    IPC分类号： A61B5/00

    CPC分类号： A61B5/4821 ,  A61B5/048 ,  A61B5/16

    摘要： A system and method for monitoring a patient experiencing an administration of at least one anesthetic drug. In certain embodiments, the method includes arranging sensors configured to acquire physiological data from a patient and reviewing the physiological data from the sensors and an indication received from an input. The method also includes assembling the physiological data into sets of time-series data and determining, from the sets of time-series data, a first set of signals in a first frequency range and a second set of signals in a second frequency range, the first set of signals describing a transient oscillation signature and the second set of signals describing a target wave signature. The method further includes identifying, using the transient oscillation and target wave signatures, a degree of sedation consistent with the administration of the anesthetic drug, and generating a report indicative of the degree of sedation induced by the drug.

    摘要翻译： 一种用于监测经历至少一种麻醉药物的给药的患者的系统和方法。 在某些实施例中，该方法包括配置用于从患者获取生理数据并且检查来自传感器的生理数据和从输入接收的指示的传感器。 该方法还包括将生理数据组合成一组时间序列数据，并从该组时间序列数据中确定第一频率范围中的第一组信号和在第二频率范围内的第二组信号， 描述瞬态振荡特征的第一组信号和描述目标波特征的第二组信号。 该方法还包括使用瞬时振荡和目标波特征识别与施用麻醉药物一致的镇静程度，以及产生指示由药物引起的镇静程度的报告。

    Systems and Methods for Tracking Non-Stationary Spectral Structure and Dynamics in Physiological Data
    2.
    发明申请
    Systems and Methods for Tracking Non-Stationary Spectral Structure and Dynamics in Physiological Data 审中-公开
    跟踪非固定光谱结构和生理数据动力学的系统和方法

    公开(公告)号：US20160150988A1

    公开(公告)日：2016-06-02

    申请号：US14900805

    申请日：2014-06-27

    申请人： Michael J. PRERAU ,  Patrick L. PURDON ,  Uri EDEN

    发明人： Michael J. Prerau ,  Patrick L. Purdon ,  Uri Eden

    IPC分类号： A61B5/04 ,  A61B5/00 ,  A61B5/048

    CPC分类号： A61B5/04012 ,  A61B5/0402 ,  A61B5/048 ,  A61B5/0488 ,  A61B5/0496 ,  A61B5/0533 ,  A61B5/4806 ,  A61B5/4821 ,  A61B5/4839 ,  A61B5/725 ,  A61B5/7253

    摘要： Systems and methods for tracking dynamic structure in physiological data are provided. In some aspects, the method includes providing physiological data, including electroencephalogram (“EEG”) data, acquired from a subject and assembling a time-frequency representation of signals from the physiological data. The method also includes generating a dynamic model of at least one non-stationary spectral feature, such as at least one non-stationary spectral peak, using the time-frequency representation and a user indication, and applying a dynamic model of at least one non-stationary spectral feature in a parameter estimation algorithm to compute concurrent estimates of spectral parameters describing the at least one non-stationary spectral feature. The method also includes tracking the spectral parameters of the at least one spectral feature over time.

    摘要翻译： 提供了生理数据跟踪动态结构的系统和方法。 在一些方面，该方法包括提供生理数据，包括从受检者获取的脑电图（“EEG”）数据，以及组合来自生理数据的信号的时间 - 频率表示。 该方法还包括使用时间频率表示和用户指示来生成至少一个非平稳频谱特征（诸如至少一个非平稳频谱峰值）的动态模型，并且应用至少一个非平稳频谱特征的动态模型， 用于计算描述所述至少一个非平稳光谱特征的光谱参数的并发估计的参数估计算法中的平稳光谱特征。 该方法还包括随时间跟踪至少一个光谱特征的光谱参数。