公开(公告)号：US20240324947A1

公开(公告)日：2024-10-03

申请号：US18578641

申请日：2022-07-21

申请人： Baylor College of Medicine

发明人： Todd Rosengart ,  Jared Mortus

IPC分类号： A61B5/00 ,  A61B5/107

CPC分类号： A61B5/4238 ,  A61B5/1073 ,  A61B5/1077 ,  A61B5/4821 ,  A61B5/6823 ,  A61B5/6831 ,  A61B5/7275 ,  A61B2562/043 ,  A61B2562/046

摘要： This disclosure addresses burdensome pulmonary aspirations and proposes a non-invasive system and device capable of detecting gastric distension as a predictive “warning sign” of aspiration risk and a treatable risk factor to reduce the risk of highly morbid and often lethal aspiration events.

公开(公告)号：US11957437B2

公开(公告)日：2024-04-16

申请号：US16643078

申请日：2018-08-28

申请人： INRIA INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE ,  ASSISTANCE PUBLIQUE HOPITAUX DE PARIS

发明人： Radomir Chabiniok ,  Dominique Chapelle ,  Arthur Le Gall ,  Philippe Moireau ,  Fabrice Vallee

IPC分类号： A61B5/02 ,  A61B5/00 ,  A61B5/021 ,  G16H50/50

CPC分类号： A61B5/02028 ,  A61B5/021 ,  A61B5/4821 ,  A61B5/4848 ,  A61B5/725 ,  G16H50/50

摘要： A cardiac device comprises a memory arranged for receiving haemodynamic data, and a computer arranged for applying a cardiovascular model comprising a cardiac model and an arterial and venous blood circulation model using the data received in the memory, and for extracting therefrom at least one cardiac activity indicator (CI).

公开(公告)号：US11819325B2

公开(公告)日：2023-11-21

申请号：US16842460

申请日：2020-04-07

申请人： Shenzhen Mindray Bio-Medical Electronics Co., Ltd.

发明人： Hui Yu ,  Shuiyang Pan ,  Wenyu Ye ,  Jian Cen ,  Fang Liu

IPC分类号： A61B5/11 ,  A61B5/22 ,  A61N1/04 ,  A61B5/00 ,  A61N1/20 ,  A61N1/36

CPC分类号： A61B5/11 ,  A61B5/1121 ,  A61B5/22 ,  A61B5/4519 ,  A61B5/4836 ,  A61B5/7278 ,  A61N1/0452 ,  A61N1/0492 ,  A61N1/20 ,  A61B5/4821 ,  A61B2562/0219 ,  A61B2562/222 ,  A61N1/36014

摘要： Disclosed are a method for measuring the level of muscle relaxation, a device thereof and an apparatus for measuring muscle relaxation, and the method respectively obtains the sampled values of the acceleration and angular velocity of the measurement site via an acceleration sensor and an angular velocity sensor or a speed sensor and an angular velocity sensor, in order to calculate the degree of muscle relaxation according to the sampled values of the acceleration and angular velocity. As the calculated results combine the sampled values of the acceleration and angular velocity of the measurement site, the accuracy of the calculated results is higher. Moreover, the measurement combines an acceleration sensor and an angular velocity sensor or a speed sensor and an angular velocity sensor, so that the apparatus for measuring muscle relaxation can be placed in any position of the measurement site without influencing the accuracy of the measured results.

公开(公告)号：US11819321B2

公开(公告)日：2023-11-21

申请号：US16272689

申请日：2019-02-11

申请人： Wisconsin Alumni Research Foundation

发明人： Guelay Bilen-Rosas ,  Humberto Gerardo Rosas

IPC分类号： A61B5/087 ,  A61B8/00 ,  A61B8/08 ,  A61B5/00 ,  A61B5/085 ,  A61B5/08 ,  A61B7/00

CPC分类号： A61B5/087 ,  A61B5/7267 ,  A61B5/742 ,  A61B5/7405 ,  A61B5/746 ,  A61B8/08 ,  A61B8/469 ,  A61B8/488 ,  A61B5/085 ,  A61B5/0816 ,  A61B5/4821 ,  A61B7/003

摘要： Described here are systems and methods for monitoring airflow changes in a patient's airway during a medical procedure or as a general patient monitoring tool. Doppler ultrasound signals are acquired from an anatomical region within the patient's airway (e.g., a tracheal wall, a cricothyroid ligament, other connective or cartilaginous tissue within the trachea, larynx, or pharynx) and parameters from those Doppler ultrasound signals are compared to baseline parameters, which may include inputting Doppler ultrasound signals to a suitably trained deep learning model or other machine learning algorithm. When a threshold change is detected, an alarm can be provided to a user to indicate respiratory compromise and/or failure, which can include early airway compromise, airway failure, and/or airway obstruction.

公开(公告)号：US20230355171A1

公开(公告)日：2023-11-09

申请号：US17996968

申请日：2021-04-23

申请人： UNIVERSIDAD POLITECNICA DE MADRID ,  FUNDACIÓN PARA LA INVESTIGAGIÓN E INNOVAGIÓN BIOMÉDICA DEL HOSPITAL UNIVERSITARIO DEL SURESTE

发明人： Agustín RODRÍGUEZ HERRERO ,  Victor PIMENTEL NARANJO ,  María Elena HERNANDO PÉREZ ,  Jose Maria CALVO VECINO ,  Alfredo ABAD GURUMETA

IPC分类号： A61B5/00 ,  A61M5/172 ,  A61M5/14 ,  A61M5/168 ,  G16H20/17

CPC分类号： A61B5/4839 ,  A61M5/1723 ,  A61M5/1408 ,  A61M5/16827 ,  A61B5/4821 ,  G16H20/17 ,  A61M2005/14208

摘要： A system automatically calculates drug infusion applicable to a patient to induce a satisfactory anesthetic state during surgery. The automatic calculation system would be determined by target values of physiological monitors to evaluate the patient's condition. Automatic infusion increases patient safety, reducing post-surgical morbidity and mortality, and reduces continuous decision-making by the specialist. An electronic system implements a MIMO-PID controller that calculates the infusion of various drugs on the basis of a control error defined by deviations in the patient's condition, which is analyzed by several monitors. The automatic drug infusions are determined by safety systems for preventing under and/or over infusion events and are complemented with correction and feedback systems.

公开(公告)号：US20230301523A1

公开(公告)日：2023-09-28

申请号：US18004240

申请日：2021-07-08

申请人： NEUROSTEER LTD.

发明人： Nathan INTRATOR

IPC分类号： A61B5/0205 ,  A61B5/256 ,  A61B5/1455 ,  A61B5/349 ,  A61B5/00 ,  A61B5/372 ,  A61B5/024

CPC分类号： A61B5/0205 ,  A61B5/256 ,  A61B5/14553 ,  A61B5/349 ,  A61B5/721 ,  A61B5/746 ,  A61B5/372 ,  A61B5/6814 ,  A61B5/02416 ,  A61B2562/0219 ,  A61B5/4821 ,  A61B5/16

摘要： A method includes receiving from a psychological and physiological sensing (PPS) device worn on a subject's head, sensor data from sensors fixed to the PPS device. The sensors may include a left-temple photoplethysmography (PPG) sensor, a right-temple PPG sensor, and an electroencephalogram (EEG) sensor coupled to the subject's head. The right and left temple PPG sensors are configured to detect pulsating blood flow in blood vessels proximal to a left and right temple region. Pulse morphology data of pulses related to the pulsating blood flow from the left-temple PPG signal and the right-temple PPG signal are determined. A possibility of a cardiac dysfunction, a cerebral dysfunction, or both in the subject may be determined based on an EEG signal, a comparison of the pulse morphology data of pulses from the left-temple PPG signal and the right-temple PPG signal, or both.

公开(公告)号：US11744471B2

公开(公告)日：2023-09-05

申请号：US17444254

申请日：2021-08-02

申请人： Masimo Corporation

发明人： Massi Joe E. Kiani ,  Michael O'Reilly

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/318 ,  A61B5/369 ,  A61B5/1455 ,  A61B5/021 ,  A61B5/024 ,  A61B5/08 ,  A61B5/087

CPC分类号： A61B5/0205 ,  A61B5/1455 ,  A61B5/318 ,  A61B5/369 ,  A61B5/4821 ,  A61B5/4839 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/743 ,  A61B5/021 ,  A61B5/024 ,  A61B5/087 ,  A61B5/0816

摘要： A non-invasive, optical-based physiological monitoring system is disclosed. In an embodiment, the non-invasive, optical-based physiological monitoring system comprises an emitter configured to emit light into a tissue site of a living patient; a detector configured to detect the emitted light after attenuation by the tissue site and output a sensor signal responsive to the detected light; and a processor configured to determine, based on the sensor signal, a first physiological parameter indicative of a level of pain of the patient.

公开(公告)号：US11642490B2

公开(公告)日：2023-05-09

申请号：US16258472

申请日：2019-01-25

申请人： Circadian Positioning Systems, Inc.

发明人： Gustavo E. Fernandes ,  Eliza Van Reen

IPC分类号： A61M21/02 ,  A61B5/01 ,  A61B5/145 ,  A61B5/00 ,  A61B5/16 ,  A61M21/00 ,  A61K9/70 ,  A61B5/1455 ,  A61B5/0205 ,  A61B5/291 ,  A61B5/398

CPC分类号： A61M21/02 ,  A61B5/01 ,  A61B5/163 ,  A61B5/4809 ,  A61B5/4815 ,  A61B5/6833 ,  A61B5/02055 ,  A61B5/1455 ,  A61B5/14517 ,  A61B5/291 ,  A61B5/398 ,  A61B5/4821 ,  A61B5/4839 ,  A61B2562/0219 ,  A61K9/7023 ,  A61M2021/0005

摘要： Disclosed are novel compositions, devices, patches, systems and methods that are useful for estimating, determining, modulating and/or improving the sleep/wake and/or circadian phase of a subject (e.g., a human subject) by the dispensing of measured quantities of agents to a subject or into an environment of the subject and the continuous monitoring and/or tracking of the subject's consciousness (e.g., sleep/wake) patterns. In certain aspects, the compositions, devices, patches, systems and methods disclosed herein are capable of delivering one or more agents to a subject in response to measured consciousness patterns estimations and circadian phase estimations, thereby aligning the subject's circadian biology to the external environment and improving the quality and duration of sleep.

公开(公告)号：US20190246927A1

公开(公告)日：2019-08-15

申请号：US15896203

申请日：2018-02-14

申请人： CERENION OY

发明人： Eero VÄYRYNEN ,  Jukka KORTELAINEN

IPC分类号： A61B5/048 ,  A61B5/00 ,  A61B5/04

CPC分类号： A61B5/048 ,  A61B5/04014 ,  A61B5/0478 ,  A61B5/4821 ,  A61B5/7225 ,  A61B5/7257 ,  A61B5/7264

摘要： An apparatus comprises a data processing unit, which causes the apparatus to: receive at least two electroencephalographic signals of a brain of a person; form a first information about at least one of the following: phase-to-phase coupling between at least two electroencephalographic signals, phase-to-amplitude coupling between at least two electroencephalographic signals and amplitude-to-phase coupling between at least two electroencephalographic signals, the first information being related to slow waves having frequencies at or lower than 1 Hz; normalize the first information; and output information about the normalized first information.

公开(公告)号：US20180333569A1

公开(公告)日：2018-11-22

申请号：US15529928

申请日：2015-11-25

申请人： SafeOp Surgical, Inc.

发明人： Robert Snow ,  Richard O'Brien

IPC分类号： A61N1/02 ,  G16H20/40

CPC分类号： A61N1/02 ,  A61B5/04001 ,  A61B5/0488 ,  A61B5/4821 ,  A61B5/4839 ,  A61B2505/05 ,  G16H20/40

摘要： Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.