摘要:
A teletherapy control system constituted of: a teletherapy management server; and a computerized tomography unit in communication with the teletherapy management server, the teletherapy management server arranged to: obtain at least one reference image of a target area; obtain from the computerized tomography unit at least one scout image of the target area; compare the obtained at least one scout image of the target area with the obtained at least one reference image of the target area; identify the location coordinates of the target area responsive to the comparison of the obtained scout image with the obtained at least one reference image; and output a control signal to a positioning device responsive to the identified location coordinates of the target area.
摘要:
The present disclosure provides an irradiation treatment apparatus having a generally vertical patient support surface, a patient securing mechanism arranged to secure a patient in a fixed relation to the patient support surface; a rotation platform secured at one end of the patient support surface and arranged to rotate the patient support surface about a generally vertical axis and optionally translate the patient support surface at least partially about a plane generally orthogonal to the generally vertical axis; an imager exhibiting a first mode in which the imager occlude radiation from a fixed beam irradiation source and a second mode in which the imager enables irradiation from the fixed beam irradiation source; and a vertical translation mechanism in communication with the patient support surface and arranged to translate the patient support surface along the generally vertical axis from a loading position to an irradiation position.
摘要:
The present disclosure provides an irradiation treatment apparatus having a generally vertical patient support surface; a patient securing mechanism arranged to secure a patient in a fixed relation to the patient support surface; a rotation platform secured at one end of the patient support surface and arranged to rotate the patient support surface about a generally vertical axis and optionally translate the patient support surface at least partially about a plane generally orthogonal to the generally vertical axis; an imager exhibiting a first mode in which the imager occludes radiation from a fixed beam irradiation source and a second mode in which the imager enables irradiation from the fixed beam irradiation source; and a vertical translation mechanism in communication with the patient support surface and arranged to translate the patient support surface along the generally vertical axis from a loading position to an irradiation position.
摘要:
The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more aliphatic carboxylic acid derivative molecules which activate parietal cells, wherein the derivatives possess delayed or sustained enhancement effect on the PPI activity compared to the non-derivatized acid molecules. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.
摘要翻译:本发明涉及包含不可逆胃H + / K + -ATP酶质子泵抑制剂(PPI)作为胃酸分泌抑制剂和一种或多种激活壁细胞的脂肪族羧酸衍生物分子的新型口服组合物,其中衍生物具有延迟或 与未衍生的酸分子相比,PPI活性持续增强作用。 本发明还涉及使用这种组合物以减少哺乳动物胃酸分泌的方法。
摘要:
A method of teletherapy preparation and treatment comprising: providing at least one treatment area comprising a fixed beam irradiation source; providing a plurality of preparation areas; securing a patient to a patient presentation platform in one of the provided preparation areas; rotating and translating the patient, in the one of the provided preparation areas, to a planned irradiation angle and position in relation to the fixed beam irradiation source of the at least one treatment area; transporting the rotated and translated patient from the one of the provided preparation areas to one of the provided at least one treatment area; and irradiating a target tissue of the rotated and translated patient from the fixed beam radiation source at the planned irradiation angle and position. Preferably, the method further comprises imaging the target tissue in the provided treatment area; and finely adjusting the rotation and translation responsive to the imaging.
摘要:
The present invention relates to methods and compositions for treating or preventing pathological conditions associated with ferrous-dependent bacteria, such as, Helicobacter pylori in which high intracellular ferrous iron concentration is required for survival and pathogenesis. The compositions of the invention comprise endoperoxide bridge-containing compounds that specifically inhibit the growth of the ferrous-dependent bacteria and preferably promote the eradication of the bacteria. The compositions, typically also include at least one active agent for treating Helicobacter sp-related gastrointestinal disorders, such as a proton pump inhibitor, an H2 blocker or a bismuth-containing compound.
摘要:
The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more aliphatic carboxylic acid derivative molecules which activate parietal cells, wherein the derivatives possess delayed or sustained enhancement effect on the PPI activity compared to the non-derivatized acid molecules. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.
摘要翻译:本发明涉及包含不可逆胃H + / K + -ATP酶质子泵抑制剂(PPI)作为胃酸分泌抑制剂和一种或多种活化壁细胞的脂肪族羧酸衍生物分子的新型口服组合物,其中衍生物具有延迟或 与未衍生的酸分子相比,PPI活性持续增强作用。 本发明还涉及使用这种组合物以减少哺乳动物胃酸分泌的方法。
摘要:
A teletherapy treatment arrangement constituted of: a control unit; a 3 dimensional imager having an effective patient plane; at least one 2 dimensional imager arranged to provide a pair of 2 dimensional images along planes generally orthogonal to the effective patient plane of the 3 dimensional imager; and a patient positioner arranged to secure a target tissue in a fixed relationship to the patient positioner, the control unit arranged to: input a planned treatment position of the patient target tissue; in the event that the planned treatment position is consonant with the effective patient plane of the 3 dimensional imager, obtain position information of the target tissue from the 3 dimensional imager, and in the event that the planned treatment position is not consonant with the effective patient plane of the 3 dimensional imager, obtain position information of the target tissue from the at least one 2 dimensional imager.
摘要:
A method of adjusting an irradiation treatment plan, the plan constituted of: obtaining a plurality of reference scans of a target tissue over a breathing cycle; obtaining a pre-treatment scan of the target tissue; identifying the reference scan whose phase is consonant with the obtained pre-treatment scan; computing at least one motion vector field between the identified reference scan and another of the plurality of reference scans different from the identified reference scan; applying the at least one computed motion vector field to one of the obtained pre-treatment scan and the another of the plurality of reference scans so as to obtain at least one synthetic scan whose phase is consonant with the other of the obtained pre-treatment scan and the another of the plurality of reference scans; and adjusting one of an irradiation dose, irradiation angle and irradiation positioning responsive to the at least one synthetic scan.
摘要:
A patient treatment arrangement is provided which includes a fixed beam irradiation source; and a patient positioning apparatus, the patient positioning apparatus comprising: a support member; a patient securing mechanism arranged to secure a patient to the patient support member; and a patient positioner in communication with the patient support member and operative to achieve positioning of the support member equivalent to rotation of the patient support member about a plurality of axes and translation of the patient support member along a plurality of axes, the patient positioner thereby providing substantially unrestricted variable angular access for irradiation of a target tissue of a patient secured to the patient securing mechanism from the fixed beam irradiation source.