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    3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE
    2.
    发明申请
    3,5-DIAMINO-6-CHLORO-N-(N-(4-(4-(2-(HEXYL(2,3,4,5,6-PENTAHYDROXYHEXYL)AMINO)ETHOXY)PHENYL)BUTYL) CARBAMIMIDOYL)PYRAZINE-2-CARBOXAMIDE 有权
    3,5-二氨基-6-氯代-N-（N-（4-（4-（2-（HEXYL（2,3,4,5,6-二羟基己基）氨基）乙氧基）苯基）丁基）卡巴咪霉素）吡嗪 -2-羧酰胺

    公开(公告)号：US20130178482A1

    公开(公告)日：2013-07-11

    申请号：US13533911

    申请日：2012-06-26

    申请人： MICHAEL R. JOHNSON

    发明人： MICHAEL R. JOHNSON

    IPC分类号： A61K31/4965 ,  A61K45/06 ,  C07D241/34

    CPC分类号： C07D241/26 ,  A61K31/4965 ,  A61K45/06 ,  C07D239/48 ,  C07D241/34

    摘要： The present invention relates to the compound of the formula: or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.

    摘要翻译： 本发明涉及下式的化合物或其药学上可接受的盐，以及含有该化合物的组合物，其制备方法和用于促进粘膜表面水合和治疗疾病的治疗方法 包括慢性阻塞性肺疾病（COPD），哮喘，支气管扩张，急性和慢性支气管炎，囊性纤维化，肺气肿和肺炎。

    Expanding concept types in conceptual graphs
    3.
    发明授权
    Expanding concept types in conceptual graphs 有权
    在概念图中扩展概念类型

    公开(公告)号：US08463808B2

    公开(公告)日：2013-06-11

    申请号：US12266671

    申请日：2008-11-07

    申请人： Bruce E. Peoples ,  Michael R. Johnson ,  Jonathon P. Smith

    发明人： Bruce E. Peoples ,  Michael R. Johnson ,  Jonathon P. Smith

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30663 ,  G06F17/30958

    摘要： In one embodiment, searching documents includes generating a query conceptual graph for a search query. The query conceptual graph has graph terms representing concept types. A set of conceptually similar terms is identified for each graph term, and the set is mapped to the concept type represented by the graph term. Documents are searched in accordance with the set of conceptually similar terms. In another embodiment, selecting a document includes determining documents that satisfy a search query expressed as a query conceptual graph. A document conceptual graph that has graph terms representing concept types is generated for each document. A set of conceptually similar terms is identified for each graph term, where the set is mapped to the concept type represented by the graph term. A document is selected if terms of the sets associated with the document match terms associated with the query conceptual graph.

    摘要翻译： 在一个实施例中，搜索文档包括生成用于搜索查询的查询概念图。 查询概念图具有表示概念类型的图形术语。 为每个图形项目识别一组概念上类似的术语，并且该集合被映射到由图形术语表示的概念类型。 根据概念上类似的术语集搜索文档。 在另一个实施例中，选择文档包括确定满足以查询概念图表示的搜索查询的文档。 为每个文档生成具有表示概念类型的图形术语的文档概念图。 为每个图形项目识别一组概念上类似的术语，其中集合被映射到由图形术语表示的概念类型。 如果与文档相关联的集合的条款匹配与查询概念图关联的术语，则选择文档。

    Countermeasure systems including pyrotechnically-gimbaled targeting units and methods for equipping vehicles with the same
    4.
    发明授权
    Countermeasure systems including pyrotechnically-gimbaled targeting units and methods for equipping vehicles with the same 有权
    对策系统包括烟火瞄准单元和装备车辆的方法

    公开(公告)号：US08424444B2

    公开(公告)日：2013-04-23

    申请号：US12848445

    申请日：2010-08-02

    申请人： Michael R. Johnson ,  Brian J. Lukow

    发明人： Michael R. Johnson ,  Brian J. Lukow

    IPC分类号： F41H5/007

    CPC分类号： F42B1/028 ,  F41G3/14 ,  F42B12/62 ,  Y10T29/49826

    摘要： Embodiments of a pyrotechnically-gimbaled targeting unit are provided. In one embodiment, the targeting unit includes a targeting unit housing, a countermeasure payload carried by the targeting unit housing, and a plurality of thrusters coupled to the targeting unit housing. The plurality of thrusters is configured to be selectively activated to rotate the targeting unit housing about first and second substantially orthogonal axes to provide controlled pointing of countermeasure payload prior to the deployment thereof. Embodiments of a countermeasure system including a pyrotechnically-gimbaled targeting unit are also provided, as are methods for equipping a vehicle with a countermeasure system of the type that includes at least one pyrotechnically-gimbaled targeting unit.

    摘要翻译： 提供烟火瞄准单元的实施例。 在一个实施例中，瞄准单元包括瞄准单元壳体，由瞄准单元壳体承载的对抗有效载荷，以及耦合到瞄准单元壳体的多个推进器。 多个推进器被配置为选择性地启动以使目标单元壳体围绕第一和第二基本上正交的轴线旋转，以在其部署之前提供对抗有效载荷的受控指向。 还提供了包括烟火 - 万向瞄准单元的对策系统的实施例，其中为车辆配备包括至少一个烟火瞄准单元类型的对策系统的方法。

    Weapon interceptor projectile with deployable frame and net
    5.
    发明授权
    Weapon interceptor projectile with deployable frame and net 有权
    武器拦截弹，具有可部署的框架和网

    公开(公告)号：US08387507B2

    公开(公告)日：2013-03-05

    申请号：US12189294

    申请日：2008-08-11

    申请人： Michael R. Johnson ,  Garrett L. Hall

    发明人： Michael R. Johnson ,  Garrett L. Hall

    IPC分类号： F41H11/00 ,  F41H13/00

    CPC分类号： F42B12/34 ,  F41H11/02 ,  F41H13/0006

    摘要： A weapon interceptor projectile has a deployable frame for maintaining a deployable net in shape. The deployable frame may be an inflatable structure, including a flexible material inflated by a gas generator. The inflatable structure has a perimeter that supports an outside shape of the net, and a series of spokes or arms that couple the perimeter to a body of the projectile. The perimeter may have an airfoil cross-section shape, reducing drag of the frame and aiding in deployment. The perimeter may be have a circular shape, giving the net a circular area. The deployable frame allows the net to maintain its shape during flight, increasing its area and its ability to come into contact with an incoming weapon, such as a rocket propelled grenade (RPG).

    摘要翻译： 武器拦截弹弹具有可部署的框架，用于维护可部署网的形状。 可展开框架可以是可充气结构，包括由气体发生器充气的柔性材料。 可膨胀结构具有支撑网的外部形状的周边，以及将周边连接到射弹的主体的一系列辐条或臂。 周边可以具有翼型截面形状，减少框架的阻力并帮助展开。 周边可以具有圆形形状，使网络成圆形区域。 可部署的框架允许网在飞行期间保持其形状，增加其面积和与进入的武器（例如火箭推进榴弹（RPG））接触的能力。

    Method and apparatus for providing a decorative surface
    7.
    发明授权
    Method and apparatus for providing a decorative surface 有权
    用于提供装饰表面的方法和装置

    公开(公告)号：US08223426B2

    公开(公告)日：2012-07-17

    申请号：US12339914

    申请日：2008-12-19

    申请人： Kenneth A. Dean ,  Michael R. Johnson ,  Jason C. Heikenfeld

    发明人： Kenneth A. Dean ,  Michael R. Johnson ,  Jason C. Heikenfeld

    IPC分类号： G02F1/29

    CPC分类号： H04M1/0283 ,  G02B26/004

    摘要： A decorative housing (11) for a mobile device (10) includes a first faceted cell (12) having a first angled electro-optic element (14) disposed therein. A second faceted cell (16) is adjacent the first cell (12) and has second angled electro-optic elements (18). A liquid (20) is in fluid communication with each faceted cell (12, 16) and moveable to a first position (22) in response to a first electric field (24) applied to one of the first and second electro-optic elements (14, 18) and moveable to a second position (26) in response to a second electric field (28) applied to the other of the first and second electro-optic elements (14, 18). An electronic modulator (30) is coupled to the first electro-optic element (14) and the second electro-optic element (18) to electronically modulate between the first electric field (24) and the second electric field (28).

    摘要翻译： 用于移动设备（10）的装饰外壳（11）包括具有设置在其中的第一倾斜电光元件（14）的第一刻面单元（12）。 第二刻面单元（16）与第一单元（12）相邻并且具有第二成角度的电光元件（18）。 响应于施加到第一和第二电光元件之一的第一电场（24），液体（20）与每个刻面单元（12,16）流体连通并且可移动到第一位置（22） 响应于施加到第一和第二电光元件（14,18）中的另一个的第二电场（28），可移动到第二位置（26）。 电子调制器（30）耦合到第一电光元件（14）和第二电光元件（18）以在第一电场（24）和第二电场（28）之间进行电子调制。

    Capped pyrazinoylguanidine sodium channel blockers
    8.
    发明授权
    Capped pyrazinoylguanidine sodium channel blockers 有权
    封闭的吡嗪基胍钠通道阻滞剂

    公开(公告)号：US08211895B2

    公开(公告)日：2012-07-03

    申请号：US12876615

    申请日：2010-09-07

    申请人： Michael R. Johnson ,  Bruce F. Molino ,  Bruce Sargent ,  Jianzhong Zhang

    发明人： Michael R. Johnson ,  Bruce F. Molino ,  Bruce Sargent ,  Jianzhong Zhang

    IPC分类号： A61K31/4965 ,  C07D241/02

    CPC分类号： C07D241/26 ,  A61K31/495 ,  A61K31/50 ,  A61K45/06

    摘要： The present application relates to pyrazinoyl guanidine sodium channel blockers having the structure: or a pharmaceutically acceptable salt thereof, where the structural variables are as defined herein. The present invention also relates pharmaceutical compositions comprising the sodium channel blockers and their use in methods of treatment, including the treatment of cardiovascular disease, cystic fibrosis, and chronic bronchitis and in the rehydration of mucosal surfaces and promotion of mucus clearance in a patient.

    摘要翻译： 本申请涉及具有以下结构的吡嗪基胍钠通道阻滞剂：或其药学上可接受的盐，其结构变量如本文所定义。 本发明还涉及包含钠通道阻滞剂的药物组合物及其在治疗方法中的用途，包括治疗心血管疾病，囊性纤维化和慢性支气管炎，以及在粘膜表面的再水化和促进患者的粘液清除。

    Searching Spoken Media According to Phonemes Derived From Expanded Concepts Expressed As Text
    10.
    发明申请
    Searching Spoken Media According to Phonemes Derived From Expanded Concepts Expressed As Text 审中-公开
    根据源自扩展概念的音素搜索口头媒体表达为文本

    公开(公告)号：US20110040774A1

    公开(公告)日：2011-02-17

    申请号：US12541244

    申请日：2009-08-14

    申请人： Bruce E. Peoples ,  Michael R. Johnson ,  Kristopher D. Barr

    发明人： Bruce E. Peoples ,  Michael R. Johnson ,  Kristopher D. Barr

    IPC分类号： G06F17/30 ,  G10L15/18 ,  G10L13/08

    CPC分类号： G06F16/685 ,  G10L2015/025

    摘要： According to one embodiment, searching media includes receiving a search query comprising search terms. At least one search term is expanded to yield a set of conceptually equivalent terms. The set of conceptually equivalent terms is converted to a set of search phonemes. Files that record phonemes are searched according to the set of search phonemes. A file that includes a phoneme that matches at least one search phoneme is selected and output to a client.

    摘要翻译： 根据一个实施例，搜索媒体包括接收包括搜索项的搜索查询。 至少有一个搜索词被扩展以产生一组概念上等效的术语。 一组概念上等效的术语被转换成一组搜索音素。 根据搜索音素集搜索记录音素的文件。 选择包含与至少一个搜索音素匹配的音素的文件，并将其输出到客户端。