Compositions including quinonoid derivatives of cannabinoids for therapeutic use
    2.
    发明授权
    Compositions including quinonoid derivatives of cannabinoids for therapeutic use 有权
    组合物包括用于治疗用途的大麻素的类醌衍生物

    公开(公告)号:US08497299B2

    公开(公告)日:2013-07-30

    申请号:US10597166

    申请日:2005-01-14

    IPC分类号: A61K31/35 C07D311/80

    摘要: The present invention relates to cannabinoic quinone compounds, and especially to their medical use. In particular five cannabinoic quinones, designated HU-331, HU-336, HU-345, HU-395 and HU-396, are described as active agents in pharmaceutical compositions. These compounds and compositions thereof are intended for the treatment of inflammatory, infectious, auto-immune and particularly hyperproliferative disorders. Thus, the compounds of the invention may be used as anti-tumor agents, or for the treatment of cancer. Furthermore, three of these compounds, HU-345, HU-395 and HU-396, are novel cannabinoic quinones.

    摘要翻译: 本发明涉及大麻醌化合物,特别涉及其医疗用途。 特别地,将五种称为HU-331,HU-336,HU-345,HU-395和HU-396的大麻醌描述为药物组合物中的活性剂。 这些化合物及其组合物旨在用于治疗炎性,感染性,自身免疫,特别是过度增殖性疾病。 因此,本发明的化合物可以用作抗肿瘤剂或用于治疗癌症。 此外,这些化合物HU-345,HU-395和HU-396中的三种是新型大麻素。

    THERAPEUTIC USE OF QUINONOID DERIVATIVES OF CANNABINOIDS
    4.
    发明申请
    THERAPEUTIC USE OF QUINONOID DERIVATIVES OF CANNABINOIDS 有权
    卡那霉素喹诺酮衍生物的治疗应用

    公开(公告)号:US20110092584A1

    公开(公告)日:2011-04-21

    申请号:US10597166

    申请日:2005-01-14

    摘要: The present invention relates to cannabinoic quinone compounds, and especially to their medical use. In particular five cannabinoic quinones, designated HU-331, HU-336, HU-345, HU-395 and HU-396 are herein described as active agents in pharmaceutical compositions. Said compounds and compositions thereof are intended for the treatment of inflammatory, infectious, auto-immune and particularly hyperproliferative disorders. Thus, the compounds of the invention may be used as anti-tumor agents, or for the treatment of cancer. Furthermore, three of these compounds, HU-345, HU-395 and HU-396, are novel cannabinoic quinones and thus are also claimed herein.

    摘要翻译: 本发明涉及大麻醌化合物,特别涉及其医疗用途。 特别地,在药物组合物中将五种称为HU-331,HU-336,HU-345,HU-395和HU-396的大麻素醌描述为活性剂。 所述化合物及其组合物旨在用于治疗炎性,感染性,自身免疫性,特别是过度增殖性疾病。 因此,本发明的化合物可以用作抗肿瘤剂或用于治疗癌症。 此外,这些化合物HU-345,HU-395和HU-396中的三种是新型大麻素醌,因此也在此要求保护。