公开(公告)号：US20120244195A1

公开(公告)日：2012-09-27

申请号：US13490405

申请日：2012-06-06

申请人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

发明人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

IPC分类号： A61K33/44 ,  A61P13/12 ,  A61P1/16 ,  A61K9/14

CPC分类号： A61K33/44 ,  Y10T428/2991

摘要： An adsorbent for an oral administration, comprising a surface-modified spherical activated carbon wherein an average particle diameter is 50 to 200 μm, a specific surface area determined by a BET method is 700 m2/g or more, a bulk density is less than 0.54 g/mL, a total amount of acidic groups is 0.30 to 1.20 meq/g, and a total amount of basic groups is 0.20 to 0.9 meq/g is disclosed. The adsorbent for an oral administration has a high adsorbability, and is capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably reducing an amount of urinary proteins excretion.

摘要翻译： 用于口服给药的吸附剂，其包含平均粒径为50〜200μm的表面改性的球形活性炭，BET法测定的比表面积为700m 2 / g以上，堆积密度小于0.54 g / mL，酸性基团的总量为0.30〜1.20meq / g，碱性基团的总量为0.20〜0.9meq / g。 用于口服的吸附剂具有高的吸附性，并且能够在保留期间在肠中吸附大量的毒素，并且显着减少尿蛋白排泄量。

公开(公告)号：US20100142015A1

公开(公告)日：2010-06-10

申请号：US12633475

申请日：2009-12-08

申请人： Mieko Kuwahara ,  Takuji Yoshida ,  Katsuyuki Akutsu

发明人： Mieko Kuwahara ,  Takuji Yoshida ,  Katsuyuki Akutsu

IPC分类号： G03H1/18 ,  G03H1/02 ,  G02B5/32 ,  G03F7/00

CPC分类号： G03H1/0272 ,  G02B5/32 ,  G02B27/0103 ,  G02B2027/0109 ,  G03F7/001 ,  G03H1/0248 ,  G03H1/04 ,  G03H1/0408 ,  G03H2001/026 ,  G03H2001/0439 ,  G03H2001/2615 ,  G03H2001/263 ,  G03H2222/18

摘要： A hologram recording film manufacturing method includes the steps of obtaining a laminated structure by alternately laminating M (where M≧2) photosensitive material precursor layers including a photosensitive material and at least one (M−1) resin layer on one another, obtaining M photosensitive material layers, where at least two interference fringes with a desired pitch and a desired slant angle are formed on each of the M photosensitive material layers, from the M photosensitive material precursor layers by irradiating the laminated structure with a reference laser light beam and an object laser light beam, and making the slant angles of the M photosensitive material layers different from each other while retaining the pitch value, which is defined on a face of the photosensitive material layer, by irradiating the laminated structure with an energy ray from the laminated structure's one face side, and heating the laminated structure.

摘要翻译： 全息记录膜制造方法包括以下步骤：通过交替层叠包含感光材料和至少一个（M-1）树脂层的M（其中M≥2）的感光材料前体层彼此层叠以获得M感光 材料层，其中通过用参考激光束和物体照射层压结构，从M个感光材料前体层形成具有期望间距和期望倾斜角的至少两个干涉条纹 激光束，并且通过用来自层叠结构体的能量射线照射层叠结构，使M感光材料层的倾斜角度彼此不同，同时保持限定在感光材料层的表面上的间距值 一面，并加热层叠结构。

公开(公告)号：US20080044477A1

公开(公告)日：2008-02-21

申请号：US11547003

申请日：2005-04-04

申请人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

发明人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

IPC分类号： A61K33/44 ,  A61K9/14 ,  A61P13/12

CPC分类号： A61K9/16 ,  A61K33/44

摘要： An adsorbent for an oral administration, comprising a spherical activated carbon wherein an average particle diameter is 50 to 200 μm, a specific surface area determined by a BET method is 700 m2/g or more, and a bulk density is less than 0.54 g/mL is disclosed. The adsorbent for an oral administration has a high adsorbability, and is capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably increasing an adsorption amount of compounds having a large molecular weight.

摘要翻译： 一种口服吸收剂，其包含平均粒径为50〜200μm的球形活性炭，BET法测定的比表面积为700m 2 / g以上， 公开了堆密度小于0.54g / mL。 用于口服的吸附剂具有高吸附性，并且能够在保留期间在肠中吸附大量的毒素，并且显着增加分子量大的化合物的吸附量。

公开(公告)号：US08440228B2

公开(公告)日：2013-05-14

申请号：US11547003

申请日：2005-04-04

申请人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

发明人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

IPC分类号： A61K33/44 ,  A61K9/14 ,  A61P13/12 ,  B01J20/02

CPC分类号： A61K9/16 ,  A61K33/44

摘要： An adsorbent for an oral administration, comprising a spherical activated carbon wherein an average particle diameter is 50 to 200 μm, a specific surface area determined by a BET method is 700 m2/g or more, and a bulk density is less than 0.54 g/mL is disclosed. The adsorbent for an oral administration has a high adsorbability, and is capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably increasing an adsorption amount of compounds having a large molecular weight.

摘要翻译： 用于口服给药的吸附剂，其包含平均粒径为50-200μm的球形活性炭，通过BET法测定的比表面积为700m 2 / g以上，堆积密度小于0.54g / mL。 用于口服的吸附剂具有高吸附性，并且能够在保留期间在肠中吸附大量的毒素，并且显着增加分子量大的化合物的吸附量。

公开(公告)号：US08865161B2

公开(公告)日：2014-10-21

申请号：US13490405

申请日：2012-06-06

申请人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

发明人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

IPC分类号： A61K33/44 ,  A61K9/14

CPC分类号： A61K33/44 ,  Y10T428/2991

摘要： An adsorbent for an oral administration, comprising a surface-modified spherical activated carbon wherein an average particle diameter is 50 to 200 μm, a specific surface area determined by a BET method is 700 m2/g or more, a bulk density is less than 0.54 g/mL, a total amount of acidic groups is 0.30 to 1.20 meq/g, and a total amount of basic groups is 0.20 to 0.9 meq/g is disclosed. The adsorbent for an oral administration has a high adsorbability, and is capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably reducing an amount of urinary proteins excretion.

摘要翻译： 用于口服给药的吸附剂，其包含平均粒径为50〜200μm的表面改性的球形活性炭，BET法测定的比表面积为700m 2 / g以上，堆积密度小于0.54 g / mL，酸性基团的总量为0.30〜1.20meq / g，碱性基团的总量为0.20〜0.9meq / g。 用于口服的吸附剂具有高的吸附性，并且能够在保留期间在肠中吸附大量的毒素，并且显着减少尿蛋白排泄量。

公开(公告)号：US20080081073A1

公开(公告)日：2008-04-03

申请号：US11547043

申请日：2005-04-04

申请人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

发明人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara

IPC分类号： A61K9/14 ,  A61K33/00 ,  A61P1/16 ,  A61P13/12

CPC分类号： A61K33/44 ,  Y10T428/2991

摘要： An adsorbent for an oral administration, comprising a surface-modified spherical activated carbon wherein an average particle diameter is 50 to 200 μm, a specific surface area determined by a BET method is 700 m2/g or more, a bulk density is less than 0.54 g/mL, a total amount of acidic groups is 0.30 to 1.20 meq/g, and a total amount of basic groups is 0.20 to 0.9 meq/g is disclosed. The adsorbent for an oral administration has a high adsorbability, and is capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably reducing an amount of urinary proteins excretion.

摘要翻译： 一种用于口服给药的吸附剂，其包含平均粒径为50至200μm的表面改性的球形活性炭，通过BET法测定的比表面积为700m 2 / g以上 ，堆积密度小于0.54g / mL，酸性基团的总量为0.30〜1.20meq / g，碱性基团的总量为0.20〜0.9meq / g。 用于口服的吸附剂具有高的吸附性，并且能够在保留期间在肠中吸附大量的毒素，并且显着减少尿蛋白排泄量。

公开(公告)号：US20080031972A1

公开(公告)日：2008-02-07

申请号：US11547501

申请日：2005-04-04

申请人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara ,  Hiroshi Ohta

发明人： Naohiro Sonobe ,  Takashi Wakahoi ,  Mieko Kuwahara ,  Hiroshi Ohta

IPC分类号： A61K33/44 ,  C01B31/02

CPC分类号： A61K33/44 ,  C01B32/336 ,  C01P2004/60 ,  C01P2004/61 ,  C01P2006/12 ,  C01P2006/14

摘要： A process for manufacturing a spherical activated carbon, characterized by comprising the steps of: (1) forming a spherical substance of a heat-fusible resin, (2) oxidizing the spherical substance of a heat-fusible resin to form a heat-infusible spherical substance, and (3) activating the heat-infusible spherical substance to form the spherical activated carbon is disclosed. According to the process for the manufacture, a spherical activated carbon having desirable properties, such as an average particle diameter, a particle size distribution, a pore volume, or a specific surface area, can be easily prepared.

摘要翻译： 一种制造球形活性炭的方法，其特征在于包括以下步骤：（1）形成热熔性树脂的球形物质，（2）将可热熔树脂的球形物质氧化以形成热熔融球形 物质，和（3）激活热不熔球形成球形活性炭。 根据制造方法，可以容易地制备具有所需性质如平均粒径，粒度分布，孔体积或比表面积的球形活性炭。

公开(公告)号：US07312914B2

公开(公告)日：2007-12-25

申请号：US11240136

申请日：2005-09-30

申请人： Kenji Shinozaki ,  Akio Yasuda ,  Kazuhiro Noda ,  Toru Udaka ,  Mieko Kuwahara

发明人： Kenji Shinozaki ,  Akio Yasuda ,  Kazuhiro Noda ,  Toru Udaka ,  Mieko Kuwahara

IPC分类号： G02F1/153

CPC分类号： G02F1/1508 ,  G02F1/15 ,  G02F2001/1515 ,  G02F2001/1519 ,  G02F2001/1635

摘要： Between each transparent pixel electrode driven by TFT as a drive device and a common electrode, a polymer layer located in contact with the transparent pixel electrode and electrically active to change in color by electrochemical oxidization or reduction and a polymeric solid electrolytic layer located in contact with the polymer layer and containing a coloring agent are interposed. Since electrochemical oxidization or reduction brings about a color change, the contrast and the black concentration can be enhanced, and bronzing after long-time use does not occur.

摘要翻译： 在由作为驱动装置的TFT驱动的每个透明像素电极和公共电极之间，与透明像素电极接触并且通过电化学氧化或还原而具有电活性而变色的聚合物层和与 聚合物层并含有着色剂。 由于电化学氧化或还原引起颜色变化，因此可以提高对比度和黑色浓度，长时间使用后不会发生烫伤。

公开(公告)号：US20060028707A1

公开(公告)日：2006-02-09

申请号：US11240136

申请日：2005-09-30

申请人： Kenji Shinozaki ,  Akio Yasuda ,  Kazuhiro Noda ,  Toru Udaka ,  Mieko Kuwahara

发明人： Kenji Shinozaki ,  Akio Yasuda ,  Kazuhiro Noda ,  Toru Udaka ,  Mieko Kuwahara

IPC分类号： G02F1/15

CPC分类号： G02F1/1508 ,  G02F1/15 ,  G02F2001/1515 ,  G02F2001/1519 ,  G02F2001/1635

摘要： Between each transparent pixel electrode driven by TFT as a drive device and a common electrode, a polymer layer located in contact with the transparent pixel electrode and electrically active to change in color by electrochemical oxidization or reduction and a polymeric solid electrolytic layer located in contact with the polymer layer and containing a coloring agent are interposed. since electrochemical oxidization or reduction brings about a color change, the contrast and the black concentration can be enhanced, and bronzing after long-time use does not occur.

摘要翻译： 在由作为驱动装置的TFT驱动的每个透明像素电极和公共电极之间，与透明像素电极接触并且通过电化学氧化或还原而具有电活性而变色的聚合物层和与 聚合物层并含有着色剂。 由于电化学氧化或还原引起颜色变化，可以提高对比度和黑色浓度，并且不会发生长时间使用后的烫金。

公开(公告)号：US06992808B2

公开(公告)日：2006-01-31

申请号：US10204948

申请日：2001-12-27

申请人： Kenji Shinozaki ,  Akio Yasuda ,  Kazuhiro Noda ,  Toru Udaka ,  Mieko Kuwahara

发明人： Kenji Shinozaki ,  Akio Yasuda ,  Kazuhiro Noda ,  Toru Udaka ,  Mieko Kuwahara

IPC分类号： G02F1/15

CPC分类号： G02F1/1508 ,  G02F1/15 ,  G02F2001/1515 ,  G02F2001/1519 ,  G02F2001/1635

摘要： Between each transparent pixel electrode driven by TFT as a drive device and a common electrode, a polymer layer located in contact with the transparent pixel electrode and electrically active to change in color by electrochemical oxidization or reduction and a polymeric solid electrolytic layer located in contact with the polymer layer and containing a coloring agent are interposed. since electrochemical oxidization or reduction brings about a color change, the contrast and the black concentration can be enhanced, and bronzing after long-time use does not occur.