公开(公告)号：US20070020700A1

公开(公告)日：2007-01-25

申请号：US11253473

申请日：2005-10-19

申请人： Charles Carpenter ,  Giosi Farace ,  Paul MacHenry ,  Brian Foster ,  Mirolee Zieba

发明人： Charles Carpenter ,  Giosi Farace ,  Paul MacHenry ,  Brian Foster ,  Mirolee Zieba

IPC分类号： G01N33/53 ,  G01N33/551

CPC分类号： G01N33/54333 ,  G01N33/558 ,  H01F1/0054

摘要： A complex including magnetic particle bound to a metal colloid. The complex may be part of a reagent for use in a method for determining analytes. The reagent may include a binding partner specific for an analyte. The reagent may further include a first label that is distinguishable from a second label that is used to detect the analyte. The reagent is used in kits and methods for detecting analytes in samples. The methods include immunoassay methods, including method where the first label is used to calibrate the assay.

摘要翻译： 包括与金属胶体结合的磁性颗粒的复合物。 复合物可以是用于测定分析物的方法中的试剂的一部分。 试剂可以包括对分析物特异的结合配偶体。 试剂可以进一步包括与用于检测分析物的第二标记区分开的第一标记。 该试剂用于检测样品中分析物的试剂盒和方法。 所述方法包括免疫测定方法，包括其中使用第一标记物校准测定法的方法。

公开(公告)号：US20070141717A1

公开(公告)日：2007-06-21

申请号：US11311567

申请日：2005-12-19

申请人： Charles Carpenter ,  Giosi Farace ,  Paul MacHenry ,  Brian Foster ,  Mirolee Zieba ,  Michael D'Angelo

发明人： Charles Carpenter ,  Giosi Farace ,  Paul MacHenry ,  Brian Foster ,  Mirolee Zieba ,  Michael D'Angelo

IPC分类号： G01N21/76

CPC分类号： G01N33/58 ,  G01N2333/635

摘要： A method and a kit for determining the presence or amount of analytes in samples over a broad potential concentration range for the analyte. The method and kit incorporate chemiluminescent and fluorescent labels conjugated to a specific binding partner for the analyte for sandwich assays, or to the analyte or an analog of the analyte for competitive assays. The conjugates are mixed with the sample and the labels are detected simultaneously or sequentially.

摘要翻译： 用于在分析物的广泛潜在浓度范围内确定样品中分析物的存在或量的方法和试剂盒。 该方法和试剂盒包含化学发光和荧光标记，其结合到用于夹心测定的分析物的特异性结合配偶体，或用于竞争性测定的分析物或分析物的类似物。 将缀合物与样品混合，同时或依次检测标记。

公开(公告)号：US20070020699A1

公开(公告)日：2007-01-25

申请号：US11184097

申请日：2005-07-19

申请人： Charles Carpenter ,  Giosi Farace ,  Paul MacHenry ,  Brian Foster ,  Mirolee Zieba

发明人： Charles Carpenter ,  Giosi Farace ,  Paul MacHenry ,  Brian Foster ,  Mirolee Zieba

IPC分类号： G01N33/53 ,  G01N33/551

CPC分类号： G01N33/54333 ,  G01N33/558 ,  H01F1/0054

摘要： A complex including magnetic particle bound to a metal colloid. The complex may be part of a reagent for use in a method for determining analytes. The reagent may include a binding partner specific for an analyte. The reagent may further include a first label that is distinguishable from a second label that is used to detect the analyte. The reagent is used in kits and methods for detecting analytes in samples. The methods include immunoassay methods, including method where the first label is used to calibrate the assay.