SURFACE FUNCTIONAL BIOACTIVE GLASS SCAFFOLD FOR BONE REGENERATION
    2.
    发明申请
    SURFACE FUNCTIONAL BIOACTIVE GLASS SCAFFOLD FOR BONE REGENERATION 审中-公开
    用于骨再生的表面功能性生物玻璃SCAFFOLD

    公开(公告)号:US20140212469A1

    公开(公告)日:2014-07-31

    申请号:US14166559

    申请日:2014-01-28

    IPC分类号: A61K9/70

    摘要: A bioactive glass scaffold treated to modify the surface of the bioactive glass scaffold for regenerating new bone tissue is disclosed. In some embodiments, the bioactive glass scaffold may include pores in a grid-like structure to promote the ingrowth of bone tissue, and the modified surface layer may include a hydroxyapatite-like surface. The bioactive glass scaffold is inexpensive and easy to fabricate and regenerates new bone faster than the existing synthetic implants. The bioactive glass scaffold may be loaded with a biomolecule, such as BMP-2, for delivery to the implantation site.

    摘要翻译: 公开了一种生物活性玻璃支架,用于修饰生物活性玻璃支架的表面以再生新的骨组织。 在一些实施方案中,生物活性玻璃支架可以包括网格状结构中的促进骨组织向内生长的孔,并且改性表面层可以包括羟基磷灰石样表面。 生物活性玻璃支架价格便宜,并且比现有的合成植入物更容易制造和再生新骨。 生物活性玻璃支架可以装载生物分子,例如BMP-2,用于递送至植入部位。