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    USE OF BETA-ADRENERGIC INVERSE AGONISTS FOR SMOKING CESSATION
    1.
    发明申请
    USE OF BETA-ADRENERGIC INVERSE AGONISTS FOR SMOKING CESSATION 有权
    用于吸烟消除的抗原反应激动剂的使用

    公开(公告)号：US20130295025A1

    公开(公告)日：2013-11-07

    申请号：US13978845

    申请日：2012-01-09

    Applicant: Richard A. Bond ,  Mitchell Glass

    Inventor： Richard A. Bond ,  Mitchell Glass

    IPC: A61K31/138 ,  A61K45/06

    CPC classification number: A61K31/138 ,  A61K9/0058 ,  A61K9/7023 ,  A61K31/403 ,  A61K31/5377 ,  A61K45/06 ,  A61K2300/00

    Abstract: The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a p-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. The invention further encompasses pharmaceutical compositions comprising the p-adrenergic inverse agonist and the additional compound.

    Abstract translation: 长期使用对肾上腺素能反向激动剂如纳多洛尔，卡维地洛和ICI-118,551提供了一种治疗粘液分泌过多的受试者粘液分泌过多的改进方法。 根据本发明的方法的一个方面是预防或控制呼吸道粘液分泌过多的方法，其包括向受试者施用治疗有效量的对肾上腺素能反向激动剂，其具有粘液分泌过多或存在粘液分泌过多的风险。 本发明还包括包含对肾上腺素能反向激动剂和另外的化合物的药物组合物。

    Treatment of cystic fibrosis
    2.
    发明授权
    Treatment of cystic fibrosis 失效
    CYSTIC FIBROSIS的治疗

    公开(公告)号：US5162348A

    公开(公告)日：1992-11-10

    申请号：US528656

    申请日：1990-05-24

    Applicant: Mitchell Glass

    Inventor： Mitchell Glass

    IPC: A61K38/00 ,  A61K38/05 ,  A61P11/00 ,  A61P31/04

    CPC classification number: A61K38/05

    Abstract: There is provided a novel therapeutic product for use in the symptomatic treatment of cystic fibrosis and for use in the manufacture of a medicament for the treatment of cystic fibrosis, as well as a method for treatment of cystic fibrosis with the therapeutic product and a method of treatment of cystic fibrosis with the therapeutic product in combination with one or more other agents indicated for the treatment of cystic fibrosis.

    Agent for therapy
    4.
    发明授权
    Agent for therapy 失效
    治疗代理

    公开(公告)号：US5128322A

    公开(公告)日：1992-07-07

    申请号：US720557

    申请日：1991-06-25

    Applicant: Mitchell Glass

    Inventor： Mitchell Glass

    IPC: A61K38/00 ,  A61K38/05 ,  A61P35/02

    CPC classification number: A61K38/05

    Abstract: There is provided a novel therapeutic agent for use in the prevention or treatment of hemorrhage associated with acute nonlymphocytic leukemia or its therapy, as well as a method of prevention or treatment of hemorrhage associated with acute nonlymphocytic leukemia or its therapy with the therapeutic agent, and a method of prevention or treatment of hemorrhage associated with acute nonlymphocytic leukemia or its therapy with the therapeutic agent in combination with one or more other agents indicated for the treatment of acute nonlymphocytic leukemia.

    Therapeutic agent for the prevention or treatment of adult respiratory distress syndrome
    6.
    发明授权
    Therapeutic agent for the prevention or treatment of adult respiratory distress syndrome 失效
    用于预防或治疗成人呼吸窘迫综合征的治疗剂

    公开(公告)号：US5338727A

    公开(公告)日：1994-08-16

    申请号：US924686

    申请日：1992-08-03

    Applicant: Mitchell Glass ,  Joseph C. Williams ,  Ross L. Stein

    Inventor： Mitchell Glass ,  Joseph C. Williams ,  Ross L. Stein

    IPC: A61K38/00 ,  A61K38/05 ,  A61P11/00 ,  A61K37/02

    CPC classification number: A61K38/05

    Abstract: There is provided a novel therapeutic agent for use in the prevention or treatment of adult respiratory distress syndrome and for use in the manufacture of a medicament for the prevention or treatment of adult respiratory distress syndrome, as well as a method of prevention or treatment of adult respiratory distress syndrome with the therapeutic agent and a method of treatment of cystic fibrosis with the therapeutic agent in combination with one or more other agents indicated for the treatment of adult respiratory distress syndrome.

    Abstract translation: 提供了用于预防或治疗成人呼吸窘迫综合征并用于制备预防或治疗成人呼吸窘迫综合征的药物的新型治疗剂，以及预防或治疗成人的方法 具有治疗剂的呼吸窘迫综合征和治疗剂与治疗成人呼吸窘迫综合征的一种或多种其它试剂组合治疗囊性纤维化的方法。

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