公开(公告)号：US20120157918A1

公开(公告)日：2012-06-21

申请号：US12968988

申请日：2010-12-15

申请人： Moises Valle ,  Giuseppe Sacca

发明人： Moises Valle ,  Giuseppe Sacca

IPC分类号： A61M5/168

CPC分类号： A61M5/16813 ,  A61M5/14216 ,  A61M5/16809 ,  A61M39/28 ,  A61M2005/1405

摘要： A patient controlled liquid drug administration device is provided that enables either or both of a continuous flow of a liquid drug, as well as successive, large-volume boluses thereof, to be self-administered to and by a patient while avoiding bolus refill during bolus delivery or after bolus delivery but before an intake stroke of the pump occurs. The device includes an elongated housing having an axial cavity extending through it with a reciprocating pump mounted at a bottom end thereof. The pump defines a closed internal reservoir and includes a first wall, or seat, that is fixed in the cavity, and a second, flexible wall that is axially movable in the cavity in relation to the fixed wall between reservoir-full and reservoir-empty positions. The pump includes an inlet port that is connectable to a source of a pressurized liquid drug by an inlet conduit, and an outlet port subcutaneously connectable to the patient by an outlet conduit, both conduits extending out the bottom end of the housing. An outlet clamp is mounted in the cavity to move between a closed position constricting the outlet conduit of the pump, thereby preventing the flow of the liquid drug through the outlet conduit, and an open position. An inlet clamp is mounted in the cavity to move between a closed position constricting the inlet conduit and thereby preventing the flow of liquid through it, and an open position disengaged from the inlet conduit, thereby allowing the flow of liquid through it.

摘要翻译： 提供一种患者控制的液体药物给药装置，其使液体药物的连续流动以及连续的大体积推注中的任一种或两者能够自动施用于患者并且由患者自发施用，同时避免在推注期间弹丸补充 输送或推料后，但在泵的进气冲程发生之前。 该装置包括细长壳体，其具有延伸穿过其的轴向空腔，其具有安装在其底端的往复泵。 泵限定了一个封闭的内部储存器，并且包括固定在空腔中的第一壁或座，以及第二柔性壁，所述第二壁柔性壁可相对于在储液器和储存器空间之间的固定壁在空腔中轴向移动 职位 该泵包括通过入口导管连接到加压液体药物源的入口端口，以及通过出口导管皮下可连接到患者的出口端口，两个延伸出外壳底端的管道。 出口夹具安装在空腔中以在限制泵的出口导管的闭合位置之间移动，从而防止液体药物流过出口导管和打开位置。 入口夹具安装在空腔中，以在限制入口管道的封闭位置之间移动，从而防止液体流过其中，并且打开位置与入口导管脱开，从而允许液体流过其中。

公开(公告)号：US20060184166A1

公开(公告)日：2006-08-17

申请号：US11060152

申请日：2005-02-16

申请人： Moises Valle ,  Steve Khalaj ,  Larry Hood ,  Dorin Panescu

发明人： Moises Valle ,  Steve Khalaj ,  Larry Hood ,  Dorin Panescu

IPC分类号： A61B18/14

CPC分类号： A61B18/14 ,  A61B90/50 ,  A61F9/0079 ,  A61F9/013

摘要： An apparatus that is used to perform a medical procedure on a cornea. The apparatus may include a ring that can be placed on a cornea and a probe that can deliver energy to denature corneal tissue. The probe can be moved about the ring and cornea by a first actuator. A second actuator may move the probe into contact with the cornea to deliver energy and denature tissue. The process of moving the probe and delivering energy can be repeated to create a circular pattern of denatured areas. The circular pattern of denatured areas may correct for hyperopia. The actuators may be controlled by a controller that operates in accordance with a program to move the probe and create the circular pattern of denatured areas in an automated process.

摘要翻译： 用于对角膜进行医疗程序的装置。 该装置可以包括可以放置在角膜上的环和可以递送能量以使角膜组织变性的探针。 探针可以通过第一致动器围绕环和角膜移动。 第二致动器可以使探针移动与角膜接触以传递能量并使组织变性。 可以重复移动探针和递送能量的过程，以产生变性区域的圆形图案。 变性区域的圆形图案可以矫正远视。 致动器可以由控制器控制，该控制器根据程序操作以移动探头并在自动化过程中创建变性区域的圆形图案。

公开(公告)号：US20050273092A1

公开(公告)日：2005-12-08

申请号：US10860529

申请日：2004-06-02

申请人： Antonio G. ,  Steve Khalaj ,  Moises Valle

发明人： Antonio G. ,  Steve Khalaj ,  Moises Valle

IPC分类号： A61B18/14

CPC分类号： A61B18/1477 ,  A61B2018/00452 ,  A61B2018/143

摘要： An apparatus and method for treating superficial skin conditions with radio frequency energy. The apparatus includes a probe that is coupled to a radio frequency console. The probe has at least one tip that can be inserted into skin tissue. Radio frequency energy can be delivered to the skin tissue through the tip. The radio frequency energy denatures tissue to cause tissue shrinkage. The tissue shrinkage can reduce or remove wrinkles, or reduce or eliminate the visual appearance of blood carrying tissue such as facial spider veins.

摘要翻译： 用射频能量治疗浅表皮肤病的装置和方法。 该装置包括耦合到射频控制台的探头。 探针至少有一个可插入皮肤组织的尖端。 射频能量可以通过尖端输送到皮肤组织。 射频能量使组织变老，导致组织收缩。 组织收缩可减少或消除皱纹，或减少或消除携带血液的组织如面部蜘蛛静脉的视觉外观。

公开(公告)号：US08308688B2

公开(公告)日：2012-11-13

申请号：US12968988

申请日：2010-12-15

申请人： Moises Valle ,  Giuseppe Sacca

发明人： Moises Valle ,  Giuseppe Sacca

IPC分类号： A61M1/00

CPC分类号： A61M5/16813 ,  A61M5/14216 ,  A61M5/16809 ,  A61M39/28 ,  A61M2005/1405

摘要： A patient controlled liquid drug administration device is provided that enables either or both of a continuous flow of a liquid drug, as well as successive, large-volume boluses thereof, to be self-administered to and by a patient while avoiding bolus refill during bolus delivery or after bolus delivery but before an intake stroke of the pump occurs. The device includes an elongated housing having an axial cavity extending through it with a reciprocating pump mounted at a bottom end thereof. The pump defines a closed internal reservoir and includes a first wall, or seat, that is fixed in the cavity, and a second, flexible wall that is axially movable in the cavity in relation to the fixed wall between reservoir-full and reservoir-empty positions. The pump includes an inlet port that is connectable to a source of a pressurized liquid drug by an inlet conduit, and an outlet port subcutaneously connectable to the patient by an outlet conduit, both conduits extending out the bottom end of the housing. An outlet clamp is mounted in the cavity to move between a closed position constricting the outlet conduit of the pump, thereby preventing the flow of the liquid drug through the outlet conduit, and an open position. An inlet clamp is mounted in the cavity to move between a closed position constricting the inlet conduit and thereby preventing the flow of liquid through it, and an open position disengaged from the inlet conduit, thereby allowing the flow of liquid through it.

摘要翻译： 提供一种患者控制的液体药物给药装置，其使液体药物的连续流动以及连续的大体积推注中的任一种或两者能够自动施用于患者并且由患者自发施用，同时避免在推注期间弹丸补充 输送或推料后，但在泵的进气冲程发生之前。 该装置包括细长壳体，其具有延伸穿过其的轴向空腔，其具有安装在其底端的往复泵。 泵限定了一个封闭的内部储存器，并且包括固定在空腔中的第一壁或座，以及第二柔性壁，所述第二壁柔性壁可相对于在储液器和储存器空间之间的固定壁在空腔中轴向移动 职位 该泵包括通过入口导管连接到加压液体药物源的入口端口，以及通过出口导管皮下可连接到患者的出口端口，两个延伸出外壳底端的管道。 出口夹具安装在空腔中以在限制泵的出口导管的闭合位置之间移动，从而防止液体药物流过出口导管和打开位置。 入口夹具安装在空腔中，以在限制入口管道的封闭位置之间移动，从而防止液体流过其中，并且打开位置与入口导管脱开，从而允许液体流过其中。