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公开(公告)号：US20220401856A1
公开(公告)日：2022-12-22
申请号：US17843542
申请日：2022-06-17
IPC分类号： B01D15/38 , C07D273/00 , C07D471/08 , C22B3/22 , C22B59/00 , C22B60/02
摘要： The present invention relates to use of a chelating compound for chromatographic separation of rare earth elements, actinides, and/or s-, p- and d-block metals, and to a method of chromatographic separation of chelates of rare earth elements, actinides and/or s-, p- and d-block metals from a mixture of at least two metal ions. The method is characterized in that it comprises the following steps: (a) providing a mixture of at least two different metal ions chosen from rare earth metal ions, actinide ions and/or s-, p- and d-block metal ions, (b) contacting metal ions comprised in said mixture to with at least one compound of general formula (I) as defined in any one of the preceding claims to form chelates; (c) subjecting the chelates from step (b) to chromatographic separation, wherein optionally at least one separated metal chelate obtained in step (c) can be subjected to at least one further chromatographic separation in order to increase the purity of the at least one separated metal chelate; and, optionally, (d) obtaining the metal from the at least one separated metal chelate.
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公开(公告)号：US11682498B2
公开(公告)日：2023-06-20
申请号：US17555131
申请日：2021-12-17
发明人： Sander De Groot , Klaas Bakker , Nicola Asquith
CPC分类号： G21G1/02 , G21C11/028 , G21G1/001 , G21C11/022 , G21C11/08 , G21G1/06 , G21G2001/0089 , G21G2001/0094
摘要： A method for the manufacture of Actinium-225 from a Radium-226 containing material. Radium-226 containing starting target material is shielded with a thermal neutron absorption shield and is subjected to neutron irradiation from a moderated nuclear reactor. Radium-226 is thereby converted into Radium-225 to provide a Radium-225-containing material. The Radium-225 in the Radium-225 containing material is allowed to decay into Actinium-225, and the Actinium-225 is isolated from the Radium-225 containing material. The neutron absorption shield shields the starting target material from neutrons having an energy in the range of 20 eV to 1000 eV.
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公开(公告)号：US20240245810A1
公开(公告)日：2024-07-25
申请号：US18437771
申请日：2024-02-09
发明人： Pieter Jos NIEUWLAND , Dion VAN DER BORN , Oene ZWAAGSTRA , Klaas BAKKER , Yulia BUCHATSKAYA , Sander DE GROOT
IPC分类号： A61K51/02
CPC分类号： A61K51/02
摘要： Method and apparatus for the generation and isolation of radionuclides comprising the steps of providing a radioactive gas, allowing the radioactive gas to decay to form charged daughter radionuclides, providing a liquid in contact with the gas, subjecting the charged daughter radionuclides (16) to an electric field between two electrodes (5,6), thereby absorbing the charged daughter radionuclides (16) in the liquid, and isolating the liquid comprising the charged daughter radionuclides (16).
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公开(公告)号：US20220108812A1
公开(公告)日：2022-04-07
申请号：US17555131
申请日：2021-12-17
发明人： Sander DE GROOT , Klaas BAKKER , Nicola ASQUITH
摘要： Method for the manufacture of Radium-225-containing material from Radium-226-containing materials by subjecting a starting material containing Radium-226 to neutron irradiation from a nuclear reactor to convert 226Ra into Radium-225 to provide a Radium-225-containing material, characterised in that the neutron irradiation of Radium-226-containing starting material is performed in a moderated nuclear reactor; and the Radium-226-containing starting material is shielded with a thermal neutron absorption shield.
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