公开(公告)号：US20070202574A1

公开(公告)日：2007-08-30

申请号：US11597638

申请日：2005-05-25

申请人： Abdelghani Zitouni ,  Nasserdine Sabaou ,  Florence Mathieu ,  Ahmed Lebrihi

发明人： Abdelghani Zitouni ,  Nasserdine Sabaou ,  Florence Mathieu ,  Ahmed Lebrihi

IPC分类号： C12P19/56 ,  C12N1/20 ,  C07H15/24 ,  A61K31/7048 ,  A61K31/704

CPC分类号： C12P17/02 ,  C07D309/10 ,  C07D407/12 ,  C07D407/14 ,  C07H15/252 ,  C12N1/20 ,  C12P15/00 ,  C12R1/04

摘要： The invention relates to a novel strain Saccharothrix actinomycete SA 103 deposited at CNCM on 16 Feb. 2004, number 1-3160 or a mutant strain thereof; a method and a medium for selection of said strain; and a method for the production of a broth, active concentrate and active compounds from a culture of said strain SA 103. The invention also relates to active compounds which can be obtained by the production method, i.e. novel mutatimycins and aldgamycins, pharmaceutical compositions comprising said active compounds and the use thereof in medicine and phytopharmaceuticals.

摘要翻译： 本发明涉及一种在CNCM于2004年2月16日保藏的新型菌株Saccharothrix放线菌SA103，编号1-3160或其突变菌株; 用于选择所述菌株的方法和介质; 以及用于从所述菌株SA103的培养物生产肉汤，活性浓缩物和活性化合物的方法。本发明还涉及可以通过制备方法获得的活性化合物，即新型的赖氨霉素和阿奇达霉素，包含所述的 活性化合物及其在医药和植物药物中的应用。