公开(公告)号：US20140057970A1

公开(公告)日：2014-02-27

申请号：US13882197

申请日：2011-10-31

申请人： Frank Schwobel ,  John Turner ,  Nicola Klare ,  Sven Klussmann

发明人： Frank Schwobel ,  John Turner ,  Nicola Klare ,  Sven Klussmann

IPC分类号： C07H21/02 ,  C07H1/06

CPC分类号： C07H21/02 ,  C07H1/06 ,  C12N15/115 ,  C12N2310/16 ,  C12N2310/3515

摘要： The present invention is related to a method for reducing the level of hepcidin in a body fluid from a subject, comprising a) providing a nucleic acid molecule capable of binding to hepcidin, and b) bringing the nucleic acid molecule into contact with a body fluid under conditions that allow for the binding of hepcidin to the nucleic acid molecule, thereby forming a complex of hepcidin and the nucleic acid molecule, and c) removing the complex from the body fluid or removing the hepcidin from the body fluid.

摘要翻译： 本发明涉及一种用于降低受试者体液中铁调素水平的方法，包括：a）提供能与铁调素结合的核酸分子，和b）使核酸分子与体液接触 在允许铁调素与核酸分子结合的条件下，从而形成铁调素和核酸分子的复合物，和c）从体液中除去复合物或从体液中除去铁调素。