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公开(公告)号:US09314481B2
公开(公告)日:2016-04-19
申请号:US13388476
申请日:2010-08-02
申请人: Richard J. Applewhite , James D. Morrison , Maurice S. Newton , Nigel P. Rhodes , Christopher J. Rickard
发明人: Richard J. Applewhite , James D. Morrison , Maurice S. Newton , Nigel P. Rhodes , Christopher J. Rickard
IPC分类号: A61K9/00 , A61K33/26 , A61K6/04 , A61K9/14 , A61K9/16 , A61K33/06 , A61K33/10 , A61K45/06 , B82Y30/00 , C01G49/00
CPC分类号: A61K33/26 , A61K6/04 , A61K9/143 , A61K9/1611 , A61K9/1682 , A61K33/06 , A61K33/10 , A61K45/06 , B82Y30/00 , C01G49/009 , C01P2002/22 , C01P2002/60 , C01P2002/72 , C01P2004/51 , C01P2004/61 , C01P2004/64 , C01P2006/11 , C01P2006/12 , C01P2006/14 , C01P2006/80 , C01P2006/82 , A61K2300/00
摘要: There is provided a method of producing a mixed metal compound comprising at least Mg2+ and at least Fe+ having an aluminium content of less than 10000 ppm, having an average crystal size of less than 20 nm (200 A) comprising the steps of: (a) combining a Mg2+ salt and a Fe3+ salt with Na2CO3 and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9 5 to 1 1, and wherein the Na2CO3 is provided at an excess of 0 to 4.0 moles than is required to complete the reaction (b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0 03 to 1.6 kW/m3 (c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt % (d) drying the crude product either by (i) heating the crude product to a temperature of no greater than 150° C. and sufficient to provide a water evaporation rate of 0.05 to 1 5 kg water per hour per kg of dry product, or (H) exposing the crude product to rapid drying at a water evaporation rate of 500 to 50000 kg water per hour per kg of dry product.
摘要翻译: 提供一种生产包含至少具有小于10000ppm的铝含量的Mg 2+和至少Fe +的混合金属化合物的方法,其平均晶体尺寸小于20nm(200),包括以下步骤:(a )将Mg2 +盐和Fe3 +盐与Na 2 CO 3和NaOH组合以产生浆料,其中浆料的pH保持在9 5至11,并且其中提供的Na 2 CO 3的过量比0至4.0摩尔 需要完成反应(b)在提供每单位体积0 03至1.6kW / m 3的功率的条件下使浆料混合(c)从混合物中分离混合的金属化合物,以获得具有干燥固体的粗产物 至少10重量%的含量(d)通过以下步骤干燥粗产物:(i)将粗产物加热到不高于150℃的温度,并且足以提供0.05至15kg水的水蒸发速率 小时/ kg干燥产物,或(H)将粗产物暴露于快速干燥 每小时每千克干燥产品的水蒸发速率为500-500千克水。
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公开(公告)号:US20120201864A1
公开(公告)日:2012-08-09
申请号:US13388476
申请日:2010-08-02
申请人: Richard J. Applewhite , James D. Morrison , Maurice S. Newton , Nigel P. Rhodes , Christopher J. Rickard
发明人: Richard J. Applewhite , James D. Morrison , Maurice S. Newton , Nigel P. Rhodes , Christopher J. Rickard
CPC分类号: A61K33/26 , A61K6/04 , A61K9/143 , A61K9/1611 , A61K9/1682 , A61K33/06 , A61K33/10 , A61K45/06 , B82Y30/00 , C01G49/009 , C01P2002/22 , C01P2002/60 , C01P2002/72 , C01P2004/51 , C01P2004/61 , C01P2004/64 , C01P2006/11 , C01P2006/12 , C01P2006/14 , C01P2006/80 , C01P2006/82 , A61K2300/00
摘要: There is provided a method of producing a mixed metal compound comprising at least Mg2+ and at least Fe+ having an aluminium content of less than 10000 ppm, having an average crystal size of less than 20 nm (200 A) comprising the steps of: (a) combining a Mg2+ salt and a Fe3+ salt with Na2CO3 and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9 5 to 1 1, and wherein the Na2CO3 is provided at an excess of 0 to 4.0 moles than is required to complete the reaction (b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0 03 to 1.6 kW/m3 (c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt % (d) drying the crude product either by (i) heating the crude product to a temperature of no greater than 150° C. and sufficient to provide a water evaporation rate of 0.05 to 1 5 kg water per hour per kg of dry product, or (H) exposing the crude product to rapid drying at a water evaporation rate of 500 to 50000 kg water per hour per kg of dry product.
摘要翻译: 提供一种生产包含至少具有小于10000ppm的铝含量的Mg 2+和至少Fe +的混合金属化合物的方法,其平均晶体尺寸小于20nm(200),包括以下步骤:(a )将Mg2 +盐和Fe3 +盐与Na 2 CO 3和NaOH组合以产生浆料,其中浆料的pH保持在9 5至11,并且其中提供的Na 2 CO 3的过量比0至4.0摩尔 需要完成反应(b)在提供每单位体积0 03至1.6kW / m 3的功率的条件下使浆料混合(c)从混合物中分离混合的金属化合物,以获得具有干燥固体的粗产物 至少10重量%的含量(d)通过以下步骤干燥粗产物:(i)将粗产物加热到不高于150℃的温度,并且足以提供0.05至15kg水的水蒸发速率 小时/ kg干燥产物,或(H)将粗产物暴露于快速干燥 每小时每千克干燥产品的水蒸发速率为500-500千克水。
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