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公开(公告)号:US4701368A
公开(公告)日:1987-10-20
申请号:US851510
申请日:1986-04-14
申请人: Masao Kiuchi , Yoshiaki Ito , Nobuyuki Ishibashi , Kazuo Yamada
发明人: Masao Kiuchi , Yoshiaki Ito , Nobuyuki Ishibashi , Kazuo Yamada
CPC分类号: D21F3/0227 , B32B27/12 , D21F3/0236 , Y10S162/901 , Y10T428/249958 , Y10T428/24996 , Y10T442/3366 , Y10T442/3813
摘要: A papermaker's pressure belt for extended nip presses, which comprises a belt base formed of a strong woven fabric having high dimensional stability, a squeezing layer to be in contact with a wet fibrous web on an extended nip press, having a large void volume and formed of a compressible elastic and porous or cellular material, such as fibrous batt, sponge or a foam resin, and formed on one side of the belt base, and an impermeable layer impermeable to oil, formed on the other side of the belt base. The squeezing layer facilitates the separation of the fibrous web from the pressure belt, while the impermeable layer inhibits the permeation of the lubricant applied to the acting surface of the pressure shoe of the extended nip press through the pressure belt.
摘要翻译: 一种用于延长辊隙压力机的造纸机压力带,其包括由具有高尺寸稳定性的强力织物形成的带基底,与扩展夹压机上的湿纤维网接触的挤压层,具有大的空隙体积并形成 可压缩的弹性和多孔或多孔材料,例如纤维毡,海绵或泡沫树脂,并且形成在带基底的一侧上,以及形成在皮带基底的另一侧上的不透油层。 挤压层有助于纤维网与压力带的分离,同时不渗透层阻止施加到延伸压区的压力靴的作用表面的润滑剂渗透通过压力带。
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公开(公告)号:US06446777B1
公开(公告)日:2002-09-10
申请号:US09630640
申请日:2000-08-01
IPC分类号: F16D4107
CPC分类号: F16D41/067 , F16D41/06
摘要: In a one-way clutch, an outer retainer includes tapered surfaces formed by chamfering axially opposite side edges of an outermost part at a projection of the outer retainer, thereby facilitating the assembly of the clutch in an outer ring. In addition, a sufficient contact width is provided between the outer ring and the projection by forming the tapered surfaces at axially opposite ends of the outer retainer, thereby preventing the occurrence of cracks in the outer retainer.
摘要翻译: 在单向离合器中,外保持器包括通过在外保持器的突起处倒角最外侧部分的轴向相对的侧边缘而形成的锥形表面,从而便于将离合器组装在外圈中。 此外,通过在外保持器的轴向相对端形成锥形表面,在外环和突起之间提供足够的接触宽度,从而防止外保持器发生裂纹。
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3.
公开(公告)号:US5599683A
公开(公告)日:1997-02-04
申请号:US283200
申请日:1994-08-04
CPC分类号: C12Q1/56 , C12Q2337/12 , G01N2333/96458
摘要: The present invention provides a method of measuring the activity of a substance to test how it inhibits or promotes the production of the blood coagulation factor XII in an active form (FXIIa). An activation reaction of the blood coagulation factor XII is initiated by adding a blood coagulation factor XII activator to an animal plasma in the presence of the tested substance. Then the reaction is stopped and the blood coagulation factor XII in an active form (FXIIa) produced in the above reaction is quantitatively determined. FXIIa plays a very important role in the initiation stage in the intrinsic blood clotting system, fibrinolysis system and plasma kallikrein-kinin system. Accordingly, the method of the present invention in which the activity of the tested substance having an inhibiting or promoting action on the production of FXIIa is measured is very highly useful in screening compounds or drugs related to blood clotting and fibrinolysis systems. It may also be used to screen compounds or drugs related to the plasma kallikrein-kinin system such as, for example, blood pressure controlling agents, antiinflammatory agents, analgesics, antiallergic agents, etc.
摘要翻译: 本发明提供一种测量物质活性以测试其如何抑制或促进活性形式的血液凝固因子XII(FXIIa)的产生的方法。 血液凝固因子XII的活化反应是通过在检测物质的存在下向动物血浆中加入血液凝固因子XII激活剂引发的。 然后停止反应,并定量测定在上述反应中产生的活性形式的血液凝固因子XII(FXIIa)。 FXIIa在内在血液凝固系统,纤维蛋白溶解系统和血浆激肽释放酶 - 激肽系统的起始阶段起着非常重要的作用。 因此,本发明的方法,其中测量对产生FXIIa具有抑制或促进作用的被测物质的活性在筛选与血液凝固和纤维蛋白溶解系统有关的化合物或药物中非常有用。 它还可用于筛选与血浆激肽释放酶 - 激肽系统相关的化合物或药物,例如血压控制剂,抗炎剂,止痛剂,抗过敏剂等。
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公开(公告)号:US5099759A
公开(公告)日:1992-03-31
申请号:US408486
申请日:1989-08-14
申请人: Saburo Sonobe , Nobuyuki Ishibashi
发明人: Saburo Sonobe , Nobuyuki Ishibashi
CPC分类号: B41N7/06 , B41N2207/02 , B41N2207/14 , Y10T29/49563
摘要: According to the invention, a surface layer consisting of a synthetic resin or rubber substance which has an ink suction property and can be subjected to surface grinding is formed on the surface of a core metal, a large number of substantially spherical grains and a recess forming substance are mixed in the surface layer, a predetermined amount of substantially spherical grains are partially exposed on a surface region of the surface layer to form a large number of mutually independent projections, and a large number of recesses are exposed on the surface layer by the recess forming substance. There are provided a printing machine ink roller which can maintain transfer function of a predetermined amount of ink for a long time period, can improve printing performance of a printing machine, and can be easily manufactured and repaired and a method of manufacturing the same.
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公开(公告)号:US5445588A
公开(公告)日:1995-08-29
申请号:US174203
申请日:1993-12-27
CPC分类号: B41N7/06 , B41N2207/02 , B41N2207/14
摘要: A printer rolling includes a surface layer roughened by forming a plurality of lattice-shaped grooves such that a large number of diamond-shaped configurations are defined by the grooves, each diamond-shaped configuration including two diagonally facing corners each having an angle of 20.degree. to 160.degree., or by forming a number of parallel grooves each forming an angle of 10.degree. to 80.degree. with the axis of the metal core, so as to form a continuous groove.
摘要翻译: 打印机滚动包括通过形成多个格子状凹槽而粗糙化的表面层,使得由凹槽限定大量菱形构造,每个菱形构造包括两个角度为20°的两个对角线对角 或者通过形成与金属芯的轴线成10°〜80°的角度的多个平行的槽,形成连续的槽。
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公开(公告)号:US07378102B2
公开(公告)日:2008-05-27
申请号:US10508327
申请日:2003-03-27
申请人: Nobuyuki Ishibashi
发明人: Nobuyuki Ishibashi
IPC分类号: A61K31/19 , A61K31/195 , A61K9/00 , A61K9/48
CPC分类号: A61K9/1617 , A61K9/4858 , A61K9/4866 , A61K31/196
摘要: The present invention relates to a diclofenac sodium oral pharmaceutical containing diclofenac sodium, a nonionic surfactant, a cholic acid derivative as an absorption promoting agent, and a glycerin or a glycol.The oral pharmaceutical has a rapid-acting effect and a good internal absorption even under non-fasting condition. Further, the pharmaceutical can be processed in a hard capsule pharmaceutical by filling it in a hard capsule as such, and has an excellent internal absorption under non-fasting condition, similarly to suppositories.
摘要翻译: 本发明涉及含有双氯芬酸钠的双氯芬酸钠口服药物,非离子表面活性剂,胆酸衍生物作为吸收促进剂,甘油或二醇。 即使在非禁食条件下,口服药物也具有快速作用和良好的内部吸收。 此外,药物可以通过将其填充在硬胶囊中而在硬胶囊药物中进行加工,并且与栓剂类似,在非空腹状态下具有优异的内部吸收。
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公开(公告)号:US5113760A
公开(公告)日:1992-05-19
申请号:US313966
申请日:1989-01-31
申请人: Saburo Sonobe , Nobuyuki Ishibashi
发明人: Saburo Sonobe , Nobuyuki Ishibashi
IPC分类号: B41N7/06
CPC分类号: B41N7/06 , B41N2207/02 , B41N2207/10 , B41N2207/14
摘要: According to a printing machine ink roller and a method of the invention for manufacturing the same, a surface layer (18) consisting of a synthetic resin or a rubber-like material, which has ink absorbency and which allows surface polishing, is arranged on a surface of a mandrel, a large number of substantially spherical particles are mixed in the surface layer (18), and a large number of independent projections (16) are formed by partially exposing predetermined substantial particles in a surface region (17) of the surface layer (18). The ink roller can maintain a function of transferring a predetermined amount of ink for a long period of time so that the performance of a printing machine can thus be improved, and such a printing machine can be very easily manufactured and repaired.
摘要翻译: PCT No.PCT / JP87 / 01001 Sec。 371日期1989年1月31日 102(e)日期1989年1月31日PCT提交1987年12月21日PCT公布。 出版物WO89 / 05732 日本1989年6月29日。根据印刷机墨辊及其制造方法,由合成树脂或橡胶状材料构成的表面层(18)具有吸墨性,并且允许 表面抛光布置在心轴的表面上,在表面层(18)中混合了大量基本上为球形的颗粒,并且通过将预定的基本颗粒部分地暴露在表面(18)中而形成大量的独立突起(16) 表面层(18)的区域(17)。 墨辊可以保持长期转印预定量的墨水的功能,从而可以提高印刷机的性能,并且这种印刷机可以非常容易地制造和修理。
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8.
公开(公告)号:US5033380A
公开(公告)日:1991-07-23
申请号:US329894
申请日:1989-03-09
申请人: Saburo Sonobe , Nobuyuki Ishibashi
发明人: Saburo Sonobe , Nobuyuki Ishibashi
CPC分类号: B41N7/06 , B41N2207/02 , B41N2207/14 , Y10T29/49563
摘要: Ink metering rollers include a core roller and a synthetic resin matrix layer formed on the periphery of the core roller. The matrix layer has a number of hemi-spherical depressions formed in its surface and also a number of hollow microballoons embedded therein. As the matrix layer of the ink metering roller is gradually worn, the hollow microballoons open in the surface of the matrix layer thereby forming spherical depressions. Hence, the spherical depressions are always distributed uniformly in the surface of the matrix layer, and hold a prescribed amount of ink. The ink metering roller therefore uniformly transfers and distributes a desired amount of ink onto the entire periphery of inking rollers associated with keyless printing machines.
摘要翻译: PCT No.PCT / JP88 / 00993 Sec。 371日期:1989年3月9日 102(e)日期1989年3月9日PCT提交1988年9月29日PCT公布。 出版物WO89 / 02833 日期:1989年4月6日。计量辊包括芯辊和形成在芯辊周边上的合成树脂基质层。 基体层在其表面上形成有多个半球形凹陷,并且还嵌有许多中空微球。 当墨水计量辊的基质层逐渐磨损时,中空微球在基体层的表面开口,从而形成球形凹陷。 因此,球面凹陷总是均匀地分布在基体层的表面上,并且保持规定量的墨。 因此,油墨计量辊将所需量的油墨均匀地转移并分配到与无键打印机相关联的上墨辊的整个周边。
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公开(公告)号:US20050214360A1
公开(公告)日:2005-09-29
申请号:US10508327
申请日:2003-03-27
申请人: Nobuyuki Ishibashi
发明人: Nobuyuki Ishibashi
IPC分类号: A61K9/16 , A61K9/48 , A61K31/196 , A61K47/10 , A61K47/14 , A61K47/28 , A61P29/00 , A61K31/195
CPC分类号: A61K9/1617 , A61K9/4858 , A61K9/4866 , A61K31/196
摘要: The present invention relates to a diclofenac sodium oral pharmaceutical containing diclofenac sodium, a nonionic surfactant, a cholic acid derivative as an absorption promoting agent, and a glycerin or a glycol. The oral pharmaceutical has a rapid-acting effect and a good internal absorption even under non-fasting condition. Further, the pharmaceutical can be processed in a hard capsule pharmaceutical by filling it in a hard capsule as such, and has an excellent internal absorption under non-fasting condition, similarly to suppositories.
摘要翻译: 本发明涉及含有双氯芬酸钠的双氯芬酸钠口服药物,非离子表面活性剂,胆酸衍生物作为吸收促进剂,甘油或二醇。 即使在非禁食条件下,口服药物也具有快速作用和良好的内部吸收。 此外,药物可以通过将其填充在硬胶囊中而以硬胶囊药物加工,并且与栓剂类似,在非空腹状态下具有优异的内部吸收。
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