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公开(公告)号：US20150342965A1
公开(公告)日：2015-12-03
申请号：US14655753
申请日：2013-12-26
申请人： OTIC PHARMA LTD.
发明人： Evgenia LOZINSKY , Yanna GALIBOV , Rodrigo YELIN
IPC分类号： A61K31/573 , A61K9/00 , A61K9/12 , A61K31/496
CPC分类号： A61K31/496 , A61K9/0046 , A61K9/107 , A61K9/12 , A61K9/122 , A61K31/4709 , A61K31/5383 , A61K31/573 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要： The present invention relates to foamable otic pharmaceutical compositions comprising oil-in-water emulsions which comprise an antibiotic agent and a propellant gas. The pharmaceutical compositions are administered to the ear as foam for treating ear disorders.
摘要翻译： 本发明涉及包含包含抗生素和推进剂气体的水包油乳液的可发泡耳用药物组合物。 将药物组合物作为治疗耳部疾病的泡沫施用于耳朵。
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公开(公告)号：US09789106B2
公开(公告)日：2017-10-17
申请号：US15385460
申请日：2016-12-20
申请人： OTIC PHARMA LTD.
发明人： Evgenia Lozinsky , Yanna Galibov , Rodrigo Yelin
IPC分类号： A61K31/496 , A61K9/107 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/26 , A61K47/12 , A61K47/20 , A61K47/38 , A61K47/32 , A61K9/12 , A61K9/00
CPC分类号： A61K31/496 , A61K9/0046 , A61K9/107 , A61K9/12 , A61K9/122 , A61K31/4709 , A61K31/5383 , A61K31/573 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要： The present invention relates a foamable otic pharmaceutical compositions comprising oil-in water emulsions which comprise an antibiotic agent and a propellant gas. The pharmaceutical compositions are administered to the ear as foam for treating ear disorders.
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公开(公告)号：US20140234227A1
公开(公告)日：2014-08-21
申请号：US14350948
申请日：2012-10-10
申请人： OTIC PHARMA LTD
发明人： Rodrigo Yelin , Jorge Danziger , Eran Eilat
IPC分类号： A61K31/573 , A61K9/12 , A61K31/496
CPC分类号： A61K9/122 , A61K9/0046 , A61K9/12 , A61K31/4709 , A61K31/496 , A61K31/573 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/38 , A61K2300/00
摘要： The present invention provides foamable pharmaceutical compositions comprising water-soluble antibiotics and anti-inflammatory steroids and methods of preparing same. Particularly, the present invention relates to oil-free pharmaceutical compositions comprising a quinolone, an anti-inflammatory steroid, a polar co-solvent, and propellant gas, administered to the ear in the form of foam for treating ear disorders.
摘要翻译： 本发明提供了包含水溶性抗生素和抗炎类固醇的可发泡药物组合物及其制备方法。 特别地，本发明涉及无水药物组合物，其包含喹诺酮，抗炎类固醇，极性助溶剂和推进剂气体，以泡沫形式施用于耳朵以治疗耳部疾病。
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公开(公告)号：US20170105991A1
公开(公告)日：2017-04-20
申请号：US15385460
申请日：2016-12-20
申请人： OTIC PHARMA LTD.
发明人： Evgenia LOZINSKY , Yanna GALIBOV , Rodrigo YELIN
IPC分类号： A61K31/496 , A61K45/06 , A61K47/06 , A61K47/10 , A61K9/00 , A61K47/26 , A61K47/12 , A61K47/20 , A61K47/38 , A61K47/32 , A61K9/107 , A61K9/12
CPC分类号： A61K31/496 , A61K9/0046 , A61K9/107 , A61K9/12 , A61K9/122 , A61K31/4709 , A61K31/5383 , A61K31/573 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要： The present invention relates a foamable otic pharmaceutical compositions comprising oil-in water emulsions which comprise an antibiotic agent and a propellant gas. The pharmaceutical compositions are administered to the ear as foam for treating ear disorders.
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公开(公告)号：US09561240B2
公开(公告)日：2017-02-07
申请号：US14655753
申请日：2013-12-26
申请人： OTIC PHARMA LTD.
发明人： Evgenia Lozinsky , Yanna Galibov , Rodrigo Yelin
IPC分类号： A61K31/573 , A61K9/12 , A61K31/4709 , A61K9/00 , A61K9/107 , A61K31/496 , A61K31/5383
CPC分类号： A61K31/496 , A61K9/0046 , A61K9/107 , A61K9/12 , A61K9/122 , A61K31/4709 , A61K31/5383 , A61K31/573 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要： The present invention relates to foamable otic pharmaceutical compositions comprising oil-in-water emulsions which comprise an antibiotic agent and a propellant gas. The pharmaceutical compositions are administered to the ear as foam for treating ear disorders.
摘要翻译： 本发明涉及包含包含抗生素和推进剂气体的水包油乳液的可发泡耳用药物组合物。 将药物组合物作为治疗耳部疾病的泡沫施用于耳朵。
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