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公开(公告)号:US20050260770A1
公开(公告)日:2005-11-24
申请号:US11094142
申请日:2005-03-31
申请人: Irun Cohen , Francisco Quintana , Eytan Domany , Gad Elizur , Peter Hagedorn
发明人: Irun Cohen , Francisco Quintana , Eytan Domany , Gad Elizur , Peter Hagedorn
IPC分类号: G01N33/543 , G01N33/564
CPC分类号: G01N33/564
摘要: A method of diagnosing an immune disease, or a predisposition thereto, in a subject is disclosed. The method comprises determining a capacity of immunoglobulins of the subject to specifically bind each antigen probe of an antigen probe set, wherein the antigen probe set comprises a plurality of antigen probes selected from the group consisting of at least a portion of a cell/tissue structure molecule, at least a portion of a heat shock protein, at least a portion of an immune system molecule, at least a portion of a homopolymeric polypeptide, at least a portion of a hormone, at least a portion of a metabolic enzyme, at least a portion of a microbial antigen, at least a portion of a molluscan antigen, at least a portion of a nucleic acid, at least a portion of a plant antigen, at least a portion of plasma molecule, and at least a portion of a tissue antigen, wherein the capacity is indicative of the immune disease or the predisposition thereto, thereby diagnosing the immune disease, or the predisposition thereto, in the subject.
摘要翻译: 公开了一种在受试者中诊断免疫疾病或其倾向的方法。 该方法包括确定受试者的免疫球蛋白的能力以特异性结合抗原探针组的每个抗原探针,其中所述抗原探针组包含多个选自下组的抗原探针:至少一部分细胞/组织结构 分子,至少一部分热休克蛋白,至少一部分免疫系统分子,至少一部分均聚多肽,至少一部分激素,代谢酶的至少一部分,至少 一部分微生物抗原,至少一部分软体动物素抗原,至少一部分核酸,至少一部分植物抗原,至少一部分血浆分子和至少一部分组织 抗原,其中所述能力指示免疫疾病或其易感性,从而诊断受试者的免疫疾病或其易感性。
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公开(公告)号:US06701673B1
公开(公告)日:2004-03-09
申请号:US08481199
申请日:1995-06-07
IPC分类号: E06B300
CPC分类号: G01V1/001 , E05F15/431 , E05Y2400/664 , E05Y2900/55 , F16P3/12 , G01B7/023
摘要: Device for restricting or controlling and regulating the movement of remote-controlled parts, more particularly parts of a vehicle bodywork as well as a process for operating the device. The device and process can be used with particular advantage as a collision protection for window winders, sunroofs, doors or flaps, more particularly in connection with electrical displacement devices for motor vehicles. The device is characterized by an actuator and a sensor which are mounted on a cohesive uninterrupted transmission path which is a constituent part of the closing surface area of the remote-controlled part and/or of the fixed part interacting therewith. The arrangement is selected so that a part of the energy supplied by actuator is converted into acoustic surface waves which can scatter over the transmission path and can be received by the sensor.
摘要翻译: 用于限制或控制和调节远程控制部件的运动的装置,更具体地说是车体的部件以及操作该装置的过程。 该装置和工艺可以特别有利地用于窗式卷取机,天窗,门或挡板的防撞保护装置,更具体地涉及用于机动车辆的电气移动装置。 该装置的特征在于,致动器和传感器安装在作为远程控制部件的闭合表面区域和/或与其相互作用的固定部件的组成部分的内聚不间断传输路径上。 选择该布置使得由致动器供应的能量的一部分被转换成可以在传输路径上散射并且可以由传感器接收的声表面波。
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公开(公告)号:US20140272998A1
公开(公告)日:2014-09-18
申请号:US14232806
申请日:2012-07-13
申请人: Ulrik Ralfkiaer , Peter Hagedorn , Charlotte Busch Ahler , Carsten Geisler , Anders Woetmann , Lone Skov , Niels Feentved Odum , Elisabeth Ralfkiaer
发明人: Ulrik Ralfkiaer , Peter Hagedorn , Charlotte Busch Ahler , Carsten Geisler , Anders Woetmann , Lone Skov , Niels Feentved Odum , Elisabeth Ralfkiaer
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
摘要: The present invention relates to the field of cancer-diagnostics. In particular the invention relates to a microRNA expression signature that allows discriminating skin samples of cutaneous T-cell lymphomas (CTCL) from non-malignant (inflammantory) skin samples by use of quantitative polymerase chain reaction performed on reverse transcribed miRNA. miR-155, miR-326, miR-663b, miR-203 and miR-205 are shown to be differentially expressed.
摘要翻译: 本发明涉及癌症诊断领域。 特别地,本发明涉及通过使用对逆转录miRNA进行的定量聚合酶链反应,允许从非恶性(炎症性)皮肤样品鉴别皮肤T细胞淋巴瘤(CTCL)的皮肤样品的微小RNA表达特征。 miR-155,miR-326,miR-663b,miR-203和miR-205显示出差异表达。
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公开(公告)号:US20130252839A1
公开(公告)日:2013-09-26
申请号:US13879877
申请日:2011-10-11
申请人: Sahar Elhanan , Eytan Domany , Irun R. Cohen , Peter Hagedorn , Christopher Malcolm Burton , Henrik Flyvbjerg , Martin P. Iversen
发明人: Sahar Elhanan , Eytan Domany , Irun R. Cohen , Peter Hagedorn , Christopher Malcolm Burton , Henrik Flyvbjerg , Martin P. Iversen
IPC分类号: G01N33/68
CPC分类号: G01N33/6884 , G01N33/6854 , G01N2800/245
摘要: The present invention relates to methods for diagnosing transplant rejection, or a condition associated with transplant rejection, such as, primary graft dysfunction in a subject, to antigen probe arrays for performing such a diagnosis, and to antigen probe sets for generating such arrays.
摘要翻译: 本发明涉及用于诊断移植排斥的方法或与移植排斥有关的病症,例如受试者的原发性移植物功能障碍,用于进行这种诊断的抗原探针阵列,以及用于产生这种阵列的抗原探针组。
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