公开(公告)号：US4666442A

公开(公告)日：1987-05-19

申请号：US711942

申请日：1985-03-15

申请人： Piero Arru ,  Gioachino Bona ,  Maria Curcio ,  Franco Vallana

发明人： Piero Arru ,  Gioachino Bona ,  Maria Curcio ,  Franco Vallana

IPC分类号： A61F2/00 ,  A61F2/24 ,  A61L27/30

CPC分类号： A61F2/2412 ,  A61F2/2409 ,  A61L27/303 ,  A61F2220/0075 ,  A61F2310/00574

摘要： A cardiac valve prosthesis comprises an annular frame and a valve sleeve with a plurality of valve flaps which are forced apart by the blood passing through the prosthesis in one direction and which are mutually coapted by blood flow in the opposite direction. The frame of the prosthesis includes a rigid or semi-rigid stent constituted by a tubular body with a ring of apertures and with first and second end edges which, in the implanted position of the prosthesis, are respectively upstream and downstream with respect to the direction of flow of the blood through the prosthesis. Biocompatible textile completely covers the rigid stent: the covering has associated suture stitches some of which extend through the apertures of the said ring to attach the covering to the stent itself. The valve sleeve includes two sheets of biological tissue sutured together and wound into a tube, the radially outermost one having a shape which substantially reproduces the shape of the stent of the frame and the radially innermost one whereof, carrying the valve flaps, has a collar end portion which can be turned outwardly of the frame at the first end edge of the stent. The valve sleeve is fixed to the frame by further suture stitches, sone of which extend through the apertures in the ends of the appendages of the frame stent. Other suture stitches connect the end edge of the collar end portion of the radially inner sheet to the covering of biocompatible textile.

摘要翻译： 心脏瓣膜假体包括环形框架和具有多个瓣膜的阀套，所述阀瓣被血液在一个方向上穿过假体而被迫使其隔开，并且通过相反方向上的血流相互叠加。 假体的框架包括刚性或半刚性支架，其由具有孔环的管状体构成，并且具有第一和第二端边缘，其在假体的植入位置中相对于方向分别在上游和下游 血液通过假体流动。 生物相容性织物完全覆盖刚性支架：覆盖物具有相关联的缝合线迹，其中一些线延伸穿过所述环的孔，以将覆盖物附着到支架本身。 阀套包括缝合在一起并缠绕在管中的两片生物组织，径向最外侧的一个生物组织具有基本上再现框架的支架形状的形状，并且承载阀瓣的径向最内侧的形状具有凸缘 端部可以在支架的第一端边缘处向框架外侧转动。 阀套通过进一步的缝合线缝合到框架上，其中的一个缝合线延伸穿过框架支架的附件的端部中的孔。 其他缝合针迹将径向内片的颈圈端部的端缘连接到生物相容性织物的覆盖物上。