MATERIALS AND METHODS FOR SUSTAINED RELEASE OF ACTIVE COMPOUNDS
    2.
    发明申请
    MATERIALS AND METHODS FOR SUSTAINED RELEASE OF ACTIVE COMPOUNDS 审中-公开
    用于持续释放活性化合物的材料和方法

    公开(公告)号:US20160279069A1

    公开(公告)日:2016-09-29

    申请号:US15082611

    申请日:2016-03-28

    摘要: The subject invention provides nanoparticle drug delivery systems and methods of making and using the same. In one aspect, the present invention provides a nanoparticle drug delivery system comprising a magnetic nanoparticle (MNP) encapsulated by at least one bilayer coating comprising a layer of drug molecules and a layer of polymer. In another aspect, a method of using the nanoparticle drug delivery system can include: administering the nanoparticle drug delivery system systemically and localizing the nanoparticles to the target treatment area. In embodiments the nanoparticle drug delivery system is used to treat HIV-AIDS.

    摘要翻译: 本发明提供纳米颗粒药物递送系统及其制备和使用方法。 在一个方面,本发明提供纳米颗粒药物递送系统,其包括由包含药物分子层和聚合物层的至少一个双层涂层包封的磁性纳米颗粒(MNP)。 在另一方面,使用纳米颗粒药物递送系统的方法可以包括:全身施用纳米颗粒药物递送系统并将纳米颗粒定位到目标治疗区域。 在实施方案中,纳米颗粒药物递送系统用于治疗HIV-AIDS。