公开(公告)号：US20100261711A1

公开(公告)日：2010-10-14

申请号：US12725763

申请日：2010-03-17

Applicant: James M. Cook ,  Rahul V. Edwankar ,  Chitra R. Edwankar ,  Shengming Huang ,  Hiteshkumar D. Jain ,  Jie Yang ,  Felix Rivas ,  Hao Zhou

Inventor： James M. Cook ,  Rahul V. Edwankar ,  Chitra R. Edwankar ,  Shengming Huang ,  Hiteshkumar D. Jain ,  Jie Yang ,  Felix Rivas ,  Hao Zhou

IPC: A61K31/5517 ,  A61K31/5513 ,  A61P25/00

CPC classification number: A61K31/5513 ,  A61K31/5517

Abstract: In preferred embodiments, the present invention provides methods of treatment and pharmaceutical compositions for the suppression, alleviation and prevention of seizures. The preferred embodiments of the present invention further relate to methods of treatment and pharmaceutical compositions using benzodiazepine derivatives that provide suppression, alleviation and prevention of seizures with reduced sedative and ataxic side effects.

Abstract translation: 在优选的实施方案中，本发明提供了用于抑制，缓解和预防癫痫发作的治疗方法和药物组合物。 本发明的优选实施方案还涉及使用苯并二氮杂衍生物的治疗方法和药物组合物，其提供抑制，缓解和预防具有降低的镇静和共济失调副作用的癫痫发作。