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公开(公告)号：US09682026B2
公开(公告)日：2017-06-20
申请号：US12058360
申请日：2008-03-28
申请人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
发明人： Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon , Richard J. Sullivan , Ralph Peter Santarpia, III , Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes
IPC分类号： A61K8/00 , A61Q11/00 , A61K8/25 , A61K8/21 , A61K8/19 , A61K8/40 , A61K8/44 , A61K8/24 , A61K31/198
摘要： This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid the salt having a pH in an unbuffered solution of less than about 7.5; an effective amount of a soluble fluoride salt; and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
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公开(公告)号：US20130142736A1
公开(公告)日：2013-06-06
申请号：US13817266
申请日：2010-08-18
摘要： Described herein, are compositions comprising an effective amount of a basic amino acid in free or salt form, and a water soluble strontium salt; and methods of making and using the same.
摘要翻译： 本文描述的是包含有效量的游离或盐形式的碱性氨基酸和水溶性锶盐的组合物; 以及制作和使用它们的方法。
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公开(公告)号：US20120088930A1
公开(公告)日：2012-04-12
申请号：US12866633
申请日：2009-02-06
IPC分类号： C07C279/14
CPC分类号： C07C277/08 , C07C279/14
摘要： The present invention provides methods to produce arginine bicarbonate more rapidly and efficiently than conventional methods.
摘要翻译： 本发明提供了比常规方法更快速和有效地生产精氨酸碳酸氢盐的方法。
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公开(公告)号：US20110059029A1
公开(公告)日：2011-03-10
申请号：US12866639
申请日：2009-02-06
申请人： Rajnish Kohli , Richard Scott Robinson , Richard j. Sullivan , Diane Commins , Nagaraja Jayaraman
发明人： Rajnish Kohli , Richard Scott Robinson , Richard j. Sullivan , Diane Commins , Nagaraja Jayaraman
CPC分类号： A61Q11/00 , A61K8/21 , A61K8/44 , A61K2800/88
摘要： A dental composition which, e.g., eliminates or substantially reduces the discomfort and pain associated with dentinal hypersensitivity and exhibits enhanced anticaries and remineralization benefits, which composition contains a first component containing a calcium source, a second component containing an anion source and at least one of the components containing a basic amino acid in free or salt form, and the first and second components being maintained separate from each other until dispensed and combined for application to teeth.
摘要翻译： 一种牙科用组合物，其例如消除或显着降低与牙本质过敏相关的不适和疼痛，并表现出增强的防龋和再矿化益处，该组合物含有含钙源的第一组分，含有阴离子源的第二组分和至少一种 含有游离或盐形式的碱性氨基酸的组分，以及第一和第二组分彼此保持分开，直至分配并组合以施用于牙齿。
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公开(公告)号：US20110041272A1
公开(公告)日：2011-02-24
申请号：US12866757
申请日：2009-02-06
申请人： Michael Prencipe , Richard Scott Robinson , Richard J. Sullivan , Rajnish Kohli , Diane Cummins
发明人： Michael Prencipe , Richard Scott Robinson , Richard J. Sullivan , Rajnish Kohli , Diane Cummins
CPC分类号： A46B11/002 , A46B11/0003 , A46B11/0041 , A46B15/0091 , A46B2200/1066
摘要： An oral care toothbrush includes a head mounted to one end of the handle containing a plurality of oral care elements. A dispenser for an oral care composition is mounted within the toothbrush. The oral care composition consists of arginine. The toothbrush is preferably made of small size and of lightweight so as to be readily portable for use away from the home.
摘要翻译： 口腔护理牙刷包括安装到手柄的一端的头部，其包含多个口腔护理元件。 用于口腔护理组合物的分配器安装在牙刷内。 口腔护理组合物由精氨酸组成。 牙刷优选地由小尺寸和重量轻制成，以便便于携带以远离家庭使用。
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公开(公告)号：US20100322988A1
公开(公告)日：2010-12-23
申请号：US12866780
申请日：2009-02-06
摘要： The present invention provides tooth-whitening compositions comprising a bleaching agent and a baste amino acid, together with devices for application thereof, and methods of use therefor.
摘要翻译： 本发明提供了包含漂白剂和糊状氨基酸的牙齿美白组合物及其应用的装置及其使用方法。
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公开(公告)号：US11612553B2
公开(公告)日：2023-03-28
申请号：US12058209
申请日：2008-03-28
申请人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.
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公开(公告)号：US10391038B2
公开(公告)日：2019-08-27
申请号：US12866766
申请日：2009-02-06
摘要： The invention provides a method of treating sensitive teeth comprising attaching a sealant composition comprising a basic amino acid to a person's tooth and allowing the basic amino acid to be slowly released over time in order to reduce chrome and/or acute tooth sensitivity together with compositions and methods of use.
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公开(公告)号：US09918918B2
公开(公告)日：2018-03-20
申请号：US12866780
申请日：2009-02-06
摘要： The present invention provides tooth-whitening compositions comprising a bleaching agent and a basic amino acid, together with devices for application thereof, and methods of use therefor.
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公开(公告)号：US20100316580A1
公开(公告)日：2010-12-16
申请号：US12866655
申请日：2009-02-06
CPC分类号： A61Q11/00 , A61K8/21 , A61K8/44 , A61K31/09 , A61K31/198 , A61K33/16 , A61K2300/00
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form and a low dosage of fluoride and to methods of using such compositions.
摘要翻译： 本发明涉及包含有效量的游离或盐形式的碱性氨基酸和低剂量氟化物的口腔护理组合物以及使用这种组合物的方法。
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