Platinum complexes of amines with dibasic acids
    3.
    发明授权
    Platinum complexes of amines with dibasic acids 失效
    胺与二元酸的铂络合物

    公开(公告)号:US4675336A

    公开(公告)日:1987-06-23

    申请号:US748788

    申请日:1985-06-26

    IPC分类号: C07F15/00 A01N55/04 A61K31/32

    CPC分类号: C07F15/0093

    摘要: Novel organic compounds of the formula ##STR1## Where R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl(C.sub.1 -C.sub.6); or R.sub.1 and R.sub.2 taken together are selected from the group consisting of ##STR2## where n is an integer 3-6, ##STR3## where m is an integer 3-6, and ##STR4## and L is selected from the group consisting of --O--, --CH.sub.2 --, ##STR5## where R.sub.3 is alkyl(C.sub.1 -C.sub.6) or --CH.sub.2 CH.sub.2 OH, which have antineoplastic activity, compositions containing the compounds and method of using the compounds to treat tumors in mammals.

    摘要翻译: 新的有机化合物,其中R 1和R 2分别选自氢和烷基(C 1 -C 6); 或者R 1和R 2一起选自由下列组成的组:其中n是3-6的整数,其中m是3-6的整数,并且L选自 -O-,-CH 2 - ,其中R 3是具有抗肿瘤活性的烷基(C 1 -C 6)或-CH 2 CH 2 OH,含有这些化合物的组合物和使用该化合物治疗哺乳动物肿瘤的方法。

    Platinum complexes of amines with novel dibasic acids
    8.
    发明授权
    Platinum complexes of amines with novel dibasic acids 失效
    胺与新二元酸的铂络合物

    公开(公告)号:US4866092A

    公开(公告)日:1989-09-12

    申请号:US31332

    申请日:1987-03-27

    IPC分类号: C07F15/00

    CPC分类号: C07F15/0093

    摘要: Novel organic compounds of the formula ##STR1## where R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl(C.sub.1 -C.sub.6); or R.sub.1 and R.sub.2 taken together are selected from the group consisting of ##STR2## where n is an integer 3-6, ##STR3## where m is an integer 3-6, and ##STR4## and L is selected from the group consisting of --O--, --CH.sub.2 --, ##STR5## and >NR.sub.3 where R.sub.3 is alkyl(C.sub.1 -C.sub.6) or --CH.sub.2 CH.sub.2 OH, which have antineoplastic activity, compositions containing the compounds and methods of using the compounds to treat tumors in mammals.

    摘要翻译: 新颖的式(Ia)的有机化合物,其中R 1和R 2分别选自氢和烷基(C 1 -C 6); 或者R 1和R 2一起选自由下列组成的组:其中n是3-6的整数,其中m是3-6的整数,并且L选自 -O-,-CH 2 - ,和NR 3,其中R 3是具有抗肿瘤活性的烷基(C 1 -C 6)或-CH 2 CH 2 OH,含有这些化合物的组合物和使用该化合物治疗哺乳动物肿瘤的方法。