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1.发明申请AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION 审中-公开水性挥发性有机化合物自由消毒剂和/或清洁组合物及其制备方法公开(公告)号：US20140135297A1
公开(公告)日：2014-05-15
申请号：US14125115
申请日：2012-06-08
申请人： Kolazi S Narayanan , Domingo Jon , Patel V. Jayanti , Liu Xuejun , Karen Winkowski , Raman Premachandran , Lindstrom Susan
发明人： Kolazi S Narayanan , Domingo Jon , Patel V. Jayanti , Liu Xuejun , Karen Winkowski , Raman Premachandran , Lindstrom Susan
摘要： The present application provides an aqueous, stable, VOC-free microemulsion based antimicrobial disinfectant and/or cleaning concentrate composition capable of inhibiting or killing gram(+), gram(−) and methicillin-resistant Staphylococcus aureus (MRSA) comprising (i) a water-soluble matrix composite made of (a) water-soluble polymer, and (b) water-soluble surfactant; (ii) a blend of antimicrobial agents comprising (a) at least one compound selected from phenols, halogenated phenols, derivatives of phenols, derivatives of halogenated phenols, bis -phenols, cresols, resorcinols, halogenated hydroxyl diphenylethers, anilides or combinations thereof; and (b) at least one compound derived from essential oils; and (iii) optionally, one or more additives. Also, there is described a method of use and process for preparing the composition.
摘要翻译： 本申请提供了一种能够抑制或杀死克隆（+），克（ - ）和耐甲氧西林金黄色葡萄球菌（MRSA）的含水稳定的无VOC的微乳液的抗微生物消毒剂和/或清洁浓缩物组合物，其包含（i） （a）水溶性聚合物和（b）水溶性表面活性剂制成的水溶性基质复合物; （ii）抗微生物剂的混合物，其包含（a）至少一种选自酚，卤代酚，酚衍生物，卤代酚衍生物，双酚，甲酚，间苯二酚，卤代羟基二苯基醚，酰苯胺或其组合的化合物; 和（b）至少一种衍生自精油的化合物; 和（iii）任选的一种或多种添加剂。 另外，描述了制备组合物的使用方法和方法。
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2.发明申请AQUEOUS-MISCIBLE OR AQUEOUS-DISPERSIBLE, VOC-FREE BIOCIDAL COMPOSITIONS FOR THE ENHANCED INHIBITION OF GRAM-NEGATIVE BACTERIAL STRAINS, AND METHOD OF PREPARING THE SAME 审中-公开水分不溶或不溶于水，不含VOC的生物活性组合物，用于增强抗坏血酸菌株的抑制作用及其制备方法公开(公告)号：US20130150239A1
公开(公告)日：2013-06-13
申请号：US13520096
申请日：2011-01-06
IPC分类号： A01N43/80
CPC分类号： A01N43/80 , A01N25/02 , A01N25/04 , A01N2300/00
摘要： Disclosed herein is an aqueous-miscible or aqueous-dispersible biocidal composition of BIT capable of exhibiting substantially enhanced biocidal activity with lesser minimum inhibitory concentration (MIC) level at faster kill rate of gram-negative bacterial strains. The biocidal composition of the present application comprises (i) BIT, (ii) at least one cationic polymer and/or at least one cationic amine surfactant, (iii) optionally one or more sequestering agents, (iv) optionally one or more aromatic aldehydes, and (v) optionally, at least one additive. The composition is volatile organic compounds (VOC) free, heat and cold stable, and has a pH of about 3.0 to about 8.5. Also, disclosed is a process for preparing the aqueous-miscible and aqueous-dispersible compositions and their applications in various fields.
摘要翻译： 本文公开了一种水混溶性或水分散性杀生物组合物，其能够以更快的革兰氏阴性细菌菌株的杀死率显示出显着增强的杀生物活性，具有较低的最小抑制浓度（MIC）水平。 本申请的杀生物组合物包含（i）BIT，（ii）至少一种阳离子聚合物和/或至少一种阳离子胺表面活性剂，（iii）任选的一种或多种螯合剂，（iv）任选的一种或多种芳族醛 ，和（v）任选的至少一种添加剂。 该组合物是挥发性有机化合物（VOC）游离，热和冷稳定，并且具有约3.0至约8.5的pH。 此外，公开了一种制备水混溶性和水分散性组合物及其在各种领域中的应用的方法。
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3.发明申请Process Of Making A Stable Aqueous Dispersion Of Concentrated, Finely Divided Particles Of A Biocide 审中-公开制备杀菌剂浓缩，细分粒子稳定水分散体的方法公开(公告)号：US20110097371A1
公开(公告)日：2011-04-28
申请号：US12933546
申请日：2009-03-30
CPC分类号： A01N25/04 , B01F17/0028 , B01F17/0092 , A01N25/30 , A01N47/12
摘要： This invention provides a process of making a stable aqueous dispersion including concentrated, finely divided particles of a water insoluble biocide active, which comprises grinding the biocide in water in the presence of a non-ionic polymeric dispersant and optionally a co-dispersant, and compositions prepared by this process.
摘要翻译： 本发明提供一种制备稳定的水性分散体的方法，其包括浓缩的，细分散的水不溶性杀生物剂活性颗粒，其包括在非离子聚合物分散剂和任选的共分散剂的存在下将生物杀伤剂在水中研磨，以及组合物 通过这个过程准备。
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4.发明申请STABLE AND AQUEOUS CONCENTRATED PRESERVATIVE COMPOSITION OF DEHYDROACETIC ACID (DHA) AND METHYLISOTHIAZOLINONE (MIT) 审中-公开脱水酸（DHA）和甲基紫罗兰酮（MIT）的稳定和浓度浓缩的保存组合物公开(公告)号：US20130267570A1
公开(公告)日：2013-10-10
申请号：US13885614
申请日：2011-11-18
CPC分类号： A01N43/80 , A01N43/16 , A01N25/30 , A01N2300/00
摘要： An aqueous, stable, highly-concentrated preservative composition comprising (i) about 5 to 50 wt % of a dehydroacetic acid (DHA) or a salt thereof; (ii) about 1 to 20 wt % of a 2-methyl-4-isothiazolin-3-one (MIT); (iii) about 0.1 to 10 wt % of at least one block copolymer; (iv) optionally, about 0.01 to 5.0 wt % of at least one sulfosuccinate surfactant; (v) optionally, about 0.01 to 5.0 wt % of at least one sequestering agent; and (vi) optionally, about 0.01 to 5.0 wt % of one or more additives. Also disclosed is a process for preparing said preservative composition.
摘要翻译： 一种水性稳定的高度浓缩的防腐剂组合物，其包含（i）约5至50重量％的脱氢乙酸（DHA）或其盐; （ii）约1至20重量％的2-甲基-4-异噻唑啉-3-酮（MIT）; （iii）约0.1至10重量％的至少一种嵌段共聚物; （iv）任选地，约0.01至5.0重量％的至少一种磺基琥珀酸盐表面活性剂; （v）任选地，约0.01至5.0重量％的至少一种螯合剂; 和（vi）任选地，约0.01至5.0重量％的一种或多种添加剂。 还公开了制备所述防腐剂组合物的方法。
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公开(公告)号：US20150126479A1
公开(公告)日：2015-05-07
申请号：US14117171
申请日：2012-05-09
IPC分类号： A01N43/80 , A01N39/00 , A01N31/02 , A01N31/06 , A01N35/04 , A01N33/12 , A01N47/44 , A01N25/02 , A01N37/10
CPC分类号： A01N43/80 , A01N25/02 , A01N31/02 , A01N31/06 , A01N33/12 , A01N35/04 , A01N37/10 , A01N39/00 , A01N47/44 , A01N31/14 , A01N31/16 , A01N35/02 , A01N35/08 , A01N37/40 , A01N2300/00
摘要： What is described herein is an environment-friendly, highly aqueous solution of 1,2-benzisothiazolin-3-one (BIT) which is free from volatile organic compounds (VOC's), glycols, derivatives of glycols, glycerols and/or derivatives of glycerols. The composition comprises: (i) about 0.1% to about 30% by wt. of BIT; (ii) about 5% to about 15% by wt. of neutralizing agent; (iii) about 50% to about 85% by wt. of water; and (iv) about 0.1% to about 5% by wt. of chelating agent. The aqueous solution of BIT may further comprise at least one water soluble form of a co-biocide. The composition is efficient in protecting aqueous media against microbial attack in various industrial applications.
摘要翻译： 本文描述的是不含挥发性有机化合物（VOC），二醇，二醇，甘油和/或甘油衍生物的1,2-苯并异噻唑啉-3-酮（BIT）的环境友好的高水溶液 。 组合物包含：（i）约0.1重量％至约30重量％ 的BIT; （ii）约5重量％至约15重量％。 的中和剂; （iii）约50％至约85％（重量） 的水; 和（iv）约0.1重量％至约5重量％。 的螯合剂。 BIT的水溶液可以进一步包含至少一种水溶性形式的辅助杀生物剂。 该组合物在各种工业应用中有效地保护水性介质免受微生物侵袭。
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6.发明申请PHOSPHATE-FREE HIGHLY CONCENTRATED AQUEOUS DISPERSION COMPOSITION OF BIOCIDES AND PROCESS FOR PREPARING THE SAME 审中-公开无磷酸盐的高浓度水性分散体组合物及其制备方法公开(公告)号：US20130203825A1
公开(公告)日：2013-08-08
申请号：US13700552
申请日：2011-05-26
摘要： A phosphate-free, highly-concentrated aqueous dispersion composition comprising at least one biocide, sulfosuccinate based surfactant, block copolymer, suspending agent, and optionally an antifoaming agent and desired additives if any. The composition of the present application is significantly stable against heat, cold, transit, storage and dilution for at least 18 months. The preferred biocides of the dispersion composition are 2-meth-4-isothiazolin-3-one (MIT), 1,2-Benzisothiazolin-3-one (BIT), 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT), 2-Octyl-4-isothiazolin-3-one (Off) 3-Iodo-2-propynylbutyl carbamate (IPBC), oxyfluorfen, thiabendazole, terbutryn, zinc pyrithione (ZnPy), bronopol, folpet, diiiron, dehydroacetic acid (DHA), dazomet and carbendazim alone or in combination. Also disclosed is a process for preparing the dispersion composition and appropriate applications thereof.
摘要翻译： 一种无磷酸盐，高浓度的水分散体组合物，其包含至少一种杀生物剂，磺基琥珀酸盐基表面活性剂，嵌段共聚物，悬浮剂和任选的消泡剂以及所需的添加剂（如果有的话）。 本申请的组合物对于热，冷，运输，储存和稀释至少18个月是显着稳定的。 分散体组合物的优选杀生物剂为2-甲基-4-异噻唑啉-3-酮（MIT），1,2-苯并异噻唑啉-3-酮（BIT），5-氯-2-甲基-4-异噻唑啉-3-酮 （CMIT），2-辛基-4-异噻唑啉-3-酮（Off）3-碘-2-丙炔基丁基氨基甲酸酯（IPBC），氧氟芬，噻苯达唑，特丁苯醚，吡啶硫酮锌（ZnPy），布洛芬，叶酸，二酮，脱氢乙酸 酸（DHA），dazomet和多菌灵单独或组合使用。 还公开了制备分散体组合物的方法及其适用的应用。
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7.发明申请PROCESS FOR PREPARATION OF STABLE, MICROENCAPSULATED AND SUSTAINED RELEASE BIOCIDAL ACTIVES AND COMPOSITION THEREOF 审中-公开制备稳定，微晶和持续释放生物活性物质的方法及其组合物公开(公告)号：US20120164203A1
公开(公告)日：2012-06-28
申请号：US13378397
申请日：2010-06-17
CPC分类号： A01N25/04 , A01N25/08 , A01N25/12 , A01N47/04 , A01N47/12 , A01N59/16 , C09D5/1612 , C09D5/1687 , A01N43/80 , A01N43/70 , A01N47/30 , A01N2300/00
摘要： Disclosed herein is a process for the preparation of a stable sustained-release biocidal composition containing microencapsulated biocide and wherein the process comprises the steps of: (i) adsorbing the biocide onto an inert carrier by grinding to attain the required particle size and wherein the ratio of biocide; inert carrier is in the range of about 1:99 to about 99:1 (ii) optionally coating with an appropriate amine or imine compound or a water resistant film forming polymer and dispersing the resultant biocide encapsulated inert carrier in an aqueous medium in the presence of suitable dispersing agent (iii) adding at least one thickening agent to re-disperse the encapsulated biocide containing partial amount of non-encapsulated biocide if any and (iv) preparing an aqueous or solvent based sustained release biocide dispersion. Also disclosed is a stable, sustained-release biocidal composition prepared by such process and uses thereof.
摘要翻译： 本文公开了一种制备含有微囊化杀生物剂的稳定的缓释杀生物组合物的方法，其中该方法包括以下步骤：（i）通过研磨将杀生物剂吸附到惰性载体上以达到所需的粒度， 的杀菌剂; 惰性载体在约1:99至约99:1的范围内（ii）任选用合适的胺或亚胺化合物或防水成膜聚合物涂覆，并将所得的杀生物剂包封的惰性载体在存在的水性介质中分散 （iii）加入至少一种增稠剂以重新分散含有部分量的未包封的杀生物剂的包封的杀生物剂，如果有的话，以及（iv）制备基于水性或溶剂的缓释杀生物剂分散体。 还公开了通过其方法和用途制备的稳定的缓释杀生物组合物。
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8.发明申请STABILIZED AQUEOUS DISPERSION OF FOLPET ANALOGUES, METHOD OF PREPARING THE SAME AND COMPOSITION THEREOF 审中-公开稳定化水分散型的水溶性分散体，其制备方法及其组合物公开(公告)号：US20130045241A1
公开(公告)日：2013-02-21
申请号：US13513084
申请日：2010-12-07
摘要： An aqueous dispersion having a mixture of a hydrolysis-sensitive biocide, an iodo-derived hydrophobic biocide and an inert carrier dispersed in water. The iodo-derived hydrophobic biocide forms a complex with the inert carrier and the hydrolysis-sensitive biocide that is dispersible in water. The hydrophobic coating includes an inert carrier and the hydrolysis-sensitive biocide may be trihalogenomethylthio phthalimide or an analogue thereof and the iodo-derived hydrophobic biocide may be iodopropynyl butylcarbamate. The aqueous dispersion may also include a water-repelling layer coating the complex.
摘要翻译： 具有水解敏感性杀生物剂，碘衍生的疏水性杀生物剂和分散在水中的惰性载体的混合物的水分散体。 碘衍生的疏水性杀生物剂与惰性载体和可分散在水中的水解敏感性杀生物剂形成络合物。 疏水性涂层包括惰性载体，水解敏感性杀生物剂可以是三卤甲基硫代邻苯二甲酰亚胺或其类似物，碘衍生的疏水性杀生物剂可以是碘代丙炔基丁基氨基甲酸酯。 水分散体还可以包括涂覆复合物的防水层。
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9.发明申请STABILIZED BIOCIDAL DISPERSION VIA SUB-MICRONIZED CARRIER PARTICLES, PROCESS FOR MAKING THE SAME AND COMPOSITION THEREOF 审中-公开通过亚微米载体颗粒的稳定的生物分散体，其制备方法及其组合物公开(公告)号：US20120171272A1
公开(公告)日：2012-07-05
申请号：US13378423
申请日：2010-06-09
CPC分类号： A01N25/04 , A01N43/40 , A01N43/653 , A01N43/80 , A01N47/12
摘要： A stabilized biocidal dispersion comprising a biocide coated or adsorbed onto stable sub-micron carrier particles and wherein sub-micronized particles are stabilized by additives having polar moieties, hydrophobic and hydrophilic segments. The sub-micron particles are selected from metal oxides like zinc oxide, titanium dioxide, cerium dioxide and silica, alumina, minerals, clays, stilbene and sub-micron carbons. Exemplary biocides include carbamates, isothiazolones, pyrithione chelates and/or trizoles. Also disclosed is a process for preparing stabilized sub-micronized carrier particles.
摘要翻译： 一种稳定的杀生物分散体，其包含涂覆或吸附在稳定的亚微米载体颗粒上的杀生物剂，并且其中亚微粉化颗粒由具有极性部分，疏水和亲水链段的添加剂稳定。 亚微米颗粒选自金属氧化物如氧化锌，二氧化钛，二氧化铈和二氧化硅，氧化铝，矿物质，粘土，二苯乙烯和亚微米级的碳。 示例性杀生物剂包括氨基甲酸酯，异噻唑啉酮，吡啶硫酮螯合物和/或三唑。 还公开了制备稳定的亚微粉化载体颗粒的方法。
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