公开(公告)号：US5869451A

公开(公告)日：1999-02-09

申请号：US764640

申请日：1996-12-11

Applicant: William J. Dower ,  Ronald W. Barrett ,  Steven E. Cwirla ,  Christian M. Gates ,  Peter J. Schatz ,  Palaniappan Balasubramanian ,  Christopher R. Wagstrom ,  Richard Wayne Hendren ,  Randoph B. DePrince ,  Surekha Podduturi ,  Qun Yin

Inventor： William J. Dower ,  Ronald W. Barrett ,  Steven E. Cwirla ,  Christian M. Gates ,  Peter J. Schatz ,  Palaniappan Balasubramanian ,  Christopher R. Wagstrom ,  Richard Wayne Hendren ,  Randoph B. DePrince ,  Surekha Podduturi ,  Qun Yin

IPC: A61K38/00 ,  A61K38/02 ,  A61P7/00 ,  A61P43/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/52 ,  C07K17/08

CPC classification number: C07K14/524 ,  A61K38/00

Abstract: Described are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics.