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公开(公告)号：US20060156440A1
公开(公告)日：2006-07-13
申请号：US10519845
申请日：2003-07-29
申请人： Dominique Michaud , Daniel Rivard , Raphael Anguenot , Sonia Trepanier , Louis-Philippe Vezina , France Brunelle
发明人： Dominique Michaud , Daniel Rivard , Raphael Anguenot , Sonia Trepanier , Louis-Philippe Vezina , France Brunelle
CPC分类号： C12N9/50 , A23L33/105 , C12Y301/01005
摘要： The present invention relates to a method for increasing the stability of endogenous proteins recovered from plant cells or plants. The preservation of endogenous proteins integrity of endogenous protein occurs by neutralizing proteolysis in crude extracts, particularly by the use of genetic alteration of plant cells or plants that express recombinant protease inhibitors or altered activity of specific target proteases.
摘要翻译： 本发明涉及增加从植物细胞或植物回收的内源性蛋白质的稳定性的方法。 通过中和粗提取物中的蛋白水解，特别是通过使用表达重组蛋白酶抑制剂的植物细胞或植物的遗传改变或特异性靶蛋白酶的改变活性来保护内源性蛋白质的完整性。
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2.发明申请FISH-DERIVED PROTEIN LYSATE, AND USES THEREOF AS IMMUNOMODULATORY AND/OR ANTI-INFLAMMATORY AGENT 审中-公开鱼衍生的蛋白质和其作为免疫调节剂和/或抗炎剂的用途公开(公告)号：US20120077747A1
公开(公告)日：2012-03-29
申请号：US13125185
申请日：2009-10-23
CPC分类号： A61K35/60 , A23L33/18 , A61K38/012
摘要： A peptide-comprising extract derived from fish is described. Also disclosed is a process for obtaining a peptide-comprising extract derived from fish, as well as an extract obtained by this process. Compositions comprising such an extract are also described. Uses of such extracts/compositions, as well as corresponding methods of treatment, for example to prevent and/or treat an inflammatory and/or immune disease-related discomfort in a subject, are also described.
摘要翻译： 描述了源自鱼的含肽提取物。 还公开了获得源自鱼的含肽提取物的方法，以及通过该方法获得的提取物。 还描述了包含这种提取物的组合物。 还描述了这样的提取物/组合物的用途以及相应的治疗方法，例如以预防和/或治疗受试者的炎症和/或免疫疾病相关的不适。
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3.发明申请公开(公告)号：US20050251885A1
公开(公告)日：2005-11-10
申请号：US10519843
申请日：2003-07-28
申请人： Dominique Michaud , Daniel Rivard , Raphael Anguenot , Sonia Trepanier , Louis-Philippe Vezina , France Brunelle
发明人： Dominique Michaud , Daniel Rivard , Raphael Anguenot , Sonia Trepanier , Louis-Philippe Vezina , France Brunelle
CPC分类号： C12N9/50 , C12N15/8257
摘要： The present invention relates to a method for enhancing the yield of recombinant protein produced in genetically transformed plants. The invention most particularly relates to a method for preventing the undesirable proteolysis of recombinant proteins after harvest of the plant, during processing of the products from the plants. Especially, this invention focuses on introducing protease inhibitors in plants to prevent undesirable proteolysis of recombinant proteins at the time of cell disruption during the extraction process.
摘要翻译： 本发明涉及提高转基因植物中产生的重组蛋白的产量的方法。 本发明最特别涉及一种用于在植物收获植物的过程中防止重组蛋白质不期望的蛋白水解的方法。 特别地，本发明着重于在植物中引入蛋白酶抑制剂，以防止在提取过程中细胞破裂时重组蛋白的不希望的蛋白水解。
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公开(公告)号：US20050055746A1
公开(公告)日：2005-03-10
申请号：US10739923
申请日：2003-12-19
CPC分类号： C07K14/8142 , C12N15/8251
摘要： The invention relates to a method for the production of plants with increased protein content in leaves, by means of introduction of recombinant DNA molecules. Said recombinant DNA molecules are introduced into the plant, by means of a transformation system and comprise a DNA sequence of plant origin, expressed in plants, the genetic product of which inhibits a protein in leaves with the enzymatic activity of an aspartate protease and/or a serene protease. The plants which displays an increased content in leaf protein are chosen.
摘要翻译： 本发明涉及通过引入重组DNA分子来生产叶中蛋白质含量增加的植物的方法。 所述重组DNA分子通过转化系统引入植物中，并且包含在植物中表达的植物来源的DNA序列，其遗传产物用天冬氨酸蛋白酶的酶活性抑制叶中的蛋白质和/或 一种宁静的蛋白酶。 选择显示叶片蛋白质含量增加的植物。
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