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公开(公告)号:US06641818B1
公开(公告)日:2003-11-04
申请号:US09723368
申请日:2000-11-28
申请人: Patricia G. Spear , Morgyn S. Warner , Robert J. Geraghty , Wanda M. Martinez , Rebecca I. Montgomery , Gary H. Cohen , Roselyn J. Eisenberg , Charles J. Whitbeck , Claude Krummenacher
发明人: Patricia G. Spear , Morgyn S. Warner , Robert J. Geraghty , Wanda M. Martinez , Rebecca I. Montgomery , Gary H. Cohen , Roselyn J. Eisenberg , Charles J. Whitbeck , Claude Krummenacher
IPC分类号: A61K39295
CPC分类号: C07K14/005 , A61K38/00 , A61K39/00 , C12N2710/16622
摘要: A cellular herpesvirus entry protein, or a mutant, a homolog, a derivative, a variant or a biologically active fragment thereof, suspended in a pharmaceutically active carrier in an amount effective to inhibit entry of an alphaherpesvirus into a cell, wherein the cellular herpesvirus entry protein is a member of the immunoglobulin superfamily, is provided and method of use thereof
摘要翻译: 悬浮在药物活性载体中的细胞疱疹病毒入口蛋白或其突变体,同源物,衍生物,变体或生物活性片段,其有效抑制α-疱疹病毒进入细胞的量,其中细胞疱疹病毒入口 蛋白质是免疫球蛋白超家族的成员,提供其使用方法
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公开(公告)号:US06303336B1
公开(公告)日:2001-10-16
申请号:US09333279
申请日:1999-06-15
IPC分类号: C12P2102
CPC分类号: C07K14/71 , A61K38/00 , C07K14/7151
摘要: The present invention provides isolated and purified polynucleotides that encode HVEM of mammalian origin, expression vectors containing those polynucleotides, host cells transformed with those expression vectors, a process of making HVEM using those polynucleotides and vectors, and isolated and purified HVEM.
摘要翻译: 本发明提供编码哺乳动物来源的HVEM的分离和纯化的多核苷酸,含有这些多核苷酸的表达载体,用那些表达载体转化的宿主细胞,使用那些多核苷酸和载体制备HVEM的方法,以及分离和纯化的HVEM。
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公开(公告)号:US06291207B1
公开(公告)日:2001-09-18
申请号:US08509024
申请日:1995-07-28
IPC分类号: C12P2102
CPC分类号: C07K14/71 , A61K38/00 , C07K14/7151
摘要: The present invention provides isolated and purified polynucleotides that encode HVEM of mammalian origin, expression vectors containing those polynucleotides, host cells transformed with those expression vectors, a process of making HVEM using those polynucleotides and vectors, and isolated and purified HVEM.
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公开(公告)号:US06573058B1
公开(公告)日:2003-06-03
申请号:US09631780
申请日:2000-08-03
IPC分类号: G01N33567
CPC分类号: C07K14/71 , A61K38/00 , C07K14/7151
摘要: The present invention provides isolated and purified polynucleotides that encode HVEM of mammalian origin, expression vectors containing those polynucleotides, host cells transformed with those expression vectors, a process of making HVEM using those polynucleotides and vectors, and isolated and purified HVEM.
摘要翻译: 本发明提供编码哺乳动物来源的HVEM的分离和纯化的多核苷酸,含有这些多核苷酸的表达载体,用那些表达载体转化的宿主细胞,使用那些多核苷酸和载体制备HVEM的方法,以及分离和纯化的HVEM。
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公开(公告)号:US06699481B2
公开(公告)日:2004-03-02
申请号:US09784887
申请日:2001-02-16
申请人: John D. Lambris , Maria Rosa Sarrias , Gary H. Cohen , Roselyn J. Eisenberg , Patricia G. Spear , Rebecca I. Montgomery
发明人: John D. Lambris , Maria Rosa Sarrias , Gary H. Cohen , Roselyn J. Eisenberg , Patricia G. Spear , Rebecca I. Montgomery
IPC分类号: A61K39245
CPC分类号: C07K7/06 , A61K38/00 , C07K7/08 , C07K7/64 , C07K14/005 , C12N2710/16622
摘要: The invention includes antiherpesviral peptides and method of generating the same.
摘要翻译: 本发明包括抗疱疹病毒肽及其产生方法。
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