-
公开(公告)号：US20240354946A1
公开(公告)日：2024-10-24
申请号：US18641343
申请日：2024-04-20
发明人： Linxi SHI , Angela Jane DA SILVA , Maksat HAYTMYRADOV , Peter Demetri OLCOTT , George Andrew ZDASIUK
CPC分类号： G06T7/0012 , G16H20/40 , G16H50/20 , G06T2207/10081 , G06T2207/10104 , G06T2207/30096
摘要： Disclosed herein are methods for determining suitability of biology-guided radiotherapy (BgRT). These methods may include converting diagnostic positron emission tomography (PET) imaging data to simulated imaging data consistent with images obtained using PET detectors of a BgRT radiotherapy system. The simulated imaging data may be used to evaluate the suitability of BgRT by evaluating a first metric indicating a contrast noise ratio for a tumor, a second metric indicating a PET tracer activity concentration, and a third metric indicating a radiation dose to the tumor. Also disclosed herein are methods for generating synthetic or simulated list mode LOR data from one or more PET images. The synthetic or simulated list mode data may be used for testing BgRT algorithms and/or determining whether BgRT is suitable for a patient.
-
公开(公告)号：US20240316365A1
公开(公告)日：2024-09-26
申请号：US18731698
申请日：2024-06-03
IPC分类号： A61N5/10
CPC分类号： A61N5/1075 , A61N5/1049 , A61N5/1064 , A61N5/1081 , A61N2005/1052 , A61N2005/1095
摘要： Disclosed herein are systems and methods for monitoring calibration of positron emission tomography (PET) systems. In some variations, the systems include an imaging assembly having a gantry comprising a plurality of positron emission detectors. A housing may be coupled to the gantry, and the housing may include a bore and a radiation source holder spaced away from a patient scan region within the bore. A processor may be configured to receive positron emission data from the positron emission detectors and to distinguish the positron emission data from the radiation source holder and from the patient scan region. A fault signal may be generated when the positron emission data from the radiation source holder exceeds one or more threshold parameters or criteria.
-
公开(公告)号：US11975220B2
公开(公告)日：2024-05-07
申请号：US16887852
申请日：2020-05-29
发明人： Brent Harper , David Larkin , David Nett
CPC分类号： A61N5/1081 , A61N5/1045 , A61N5/1049 , A61N2005/005 , A61N2005/1052 , A61N2005/1091 , A61N2005/1094 , G21K1/046
摘要： Disclosed herein are radiation therapy systems and methods. These radiation therapy systems and methods are used for emission-guided radiation therapy, where gamma rays from markers or tracers that are localized to patient tumor regions are detected and used to direct radiation to the tumor. The radiation therapy systems described herein comprise a gantry comprising a rotatable ring coupled to a stationary frame via a rotating mechanism such that the rotatable ring rotates up to about 70 RPM, a radiation source (e.g., MV X-ray source) mounted on the rotatable ring, and one or more PET detectors mounted on the rotatable ring.
-
公开(公告)号：US20230285777A1
公开(公告)日：2023-09-14
申请号：US18311069
申请日：2023-05-02
CPC分类号： A61N5/1049 , A61B6/037 , A61N2005/1052 , A61N2005/1051 , A61N2005/1059
摘要： Disclosed herein are methods for determining the location of a moving target region (e.g., a tumor) based on the location of the center of its range of motion and the location of a target region surrogate, during a radiotherapy treatment session or a quality assurance (QA) session. These methods comprise characterizing the motion range of the target region, calculating the location of the center of the motion range, and determining a correlation between the position of the target region surrogate and the displacement of the target region from the center of the motion range as the target region moves.
-
公开(公告)号：US11633626B2
公开(公告)日：2023-04-25
申请号：US17235812
申请日：2021-04-20
IPC分类号： A61N5/10
摘要： Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.
-
公开(公告)号：US20230087425A1
公开(公告)日：2023-03-23
申请号：US17877719
申请日：2022-07-29
发明人： Debashish PAL , Ayan MITRA , Christopher Eric BROWN , Peter Demetri OLCOTT , Yevgen VORONENKO , Rostem BASSALOW
IPC分类号： A61N5/10
摘要： Systems and methods for shuttle mode radiation delivery are described herein. One method for radiation delivery comprises moving the patient platform through the patient treatment region multiple times during a treatment session. This may be referred to as patient platform or couch shuttling (i.e., couch shuttle mode). Another method for radiation delivery comprises moving the therapeutic radiation source jaw across a range of positions during a treatment session. The jaw may move across the same range of positions multiple times during a treatment session. This may be referred to as jaw shuttling (i.e., jaw shuttle mode). Some methods combine couch shuttle mode and jaw shuttle mode. Methods of dynamic or pipelined normalization are also described.
-
公开(公告)号：US20220395707A1
公开(公告)日：2022-12-15
申请号：US17852067
申请日：2022-06-28
摘要： Disclosed herein are systems and methods for real-time monitoring of patient position and/or location during a radiation treatment session. Images acquired of a patient during a treatment session can be used to calculate the patient's position and/or location with respect to the components of the radiation therapy system. One variation of a radiation therapy system includes a circular gantry with a rotatable ring coupled to a stationary frame, a therapeutic radiation source mounted on the rotatable ring, and a patient-monitoring imaging system mounted on the rotatable ring. The patient-monitoring system may have one or more image sensors or cameras disposed on the rotatable ring within a bore region of the radiation therapy system, and may be configured to acquire image data as the ring rotates.
-
公开(公告)号：US20220288422A1
公开(公告)日：2022-09-15
申请号：US17831105
申请日：2022-06-02
发明人： Yevgen VORONENKO , Jayakrishnan JANARDHANAN , Debashish PAL , Rostem BASSALOW , Peter Demetri OLCOTT , Michael Kirk OWENS
摘要： Described herein are methods for beam station delivery of radiation treatment, where the patient platform is moved to a series of discrete patient platform locations or beam stations that are determined during treatment planning, stopped at each of these locations while the radiation source rotates about the patient delivering radiation to the target regions that intersect the radiation beam path, and then moving to the next location after the prescribed dose of radiation (e.g., in accordance with a calculated fluence map) for that location has been delivered to the patient.
-
公开(公告)号：US20220096867A1
公开(公告)日：2022-03-31
申请号：US17485059
申请日：2021-09-24
发明人： Samuel MAZIN , Akshay NANDURI
摘要： Described herein are systems and methods for positioning a radiation source with respect to one or more regions of interest in a coordinate system. Such systems and methods may be used in emission guided radiation therapy (EGRT) for the localized delivery of radiation to one or more patient tumor regions. These systems comprise a gantry movable about a patient area, where a plurality of positron emission detectors, a radiation source are arranged movably on the gantry, and a controller. The controller is configured to identify a coincident positron annihilation emission path and to position the radiation source to apply a radiation beam along the identified emission path. The systems and methods described herein can be used alone or in conjunction with surgery, chemotherapy, and/or brachytherapy for the treatment of tumors.
-
公开(公告)号：US11287540B2
公开(公告)日：2022-03-29
申请号：US16887896
申请日：2020-05-29
摘要： Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac.
-
-
-
-
-
-
-
-
-
搜索结果
132 条记录 (耗时 0.035 秒)
