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1.Conformationally restricted urea inhibitors of soluble epoxide hydrolase 有权
标题翻译: 构象限制的可溶性环氧化物水解酶的脲抑制剂公开(公告)号:US08501783B2
公开(公告)日:2013-08-06
申请号:US13455861
申请日:2012-04-25
申请人: Bruce D. Hammock , Paul D. Jones , Christophe Morisseau , Huazhang Huang , Hsing-Ju Tsai , Richard Gless, Jr.
发明人: Bruce D. Hammock , Paul D. Jones , Christophe Morisseau , Huazhang Huang , Hsing-Ju Tsai , Richard Gless, Jr.
IPC分类号: A61K31/445
CPC分类号: C07D211/58 , C07D209/08 , C07D211/26 , C07D211/96 , C07D213/40 , C07D235/30 , C07D295/20 , C07D295/205 , C07D401/06 , C07D401/12 , C07D487/18 , C12Q1/34
摘要: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
摘要翻译: 提供了可溶性环氧化物水解酶(sEH)的抑制剂,其包含多个药效团并且可用于治疗疾病。
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2.CONFORMATIONALLY RESTRICTED UREA INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE 有权
标题翻译: 可溶性环氧化物水解物的一致的限制性尿素抑制剂公开(公告)号:US20130137726A1
公开(公告)日:2013-05-30
申请号:US13455861
申请日:2012-04-25
申请人: Bruce D. Hammock , Paul D. Jones , Christophe Morisseau , Huazhang Huang , Hsing-Ju Tsai , Richard Gless, JR.
发明人: Bruce D. Hammock , Paul D. Jones , Christophe Morisseau , Huazhang Huang , Hsing-Ju Tsai , Richard Gless, JR.
IPC分类号: C07D211/58 , C07D211/96 , C07D401/06
CPC分类号: C07D211/58 , C07D209/08 , C07D211/26 , C07D211/96 , C07D213/40 , C07D235/30 , C07D295/20 , C07D295/205 , C07D401/06 , C07D401/12 , C07D487/18 , C12Q1/34
摘要: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
摘要翻译: 提供了可溶性环氧化物水解酶(sEH)的抑制剂,其包含多个药效团并且可用于治疗疾病。
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