公开(公告)号：US20060275303A1

公开(公告)日：2006-12-07

申请号：US10787497

申请日：2004-02-26

Applicant: Robert Bals ,  Andreas Koczulla ,  Georg Degenfeld-Schonburg

Inventor： Robert Bals ,  Andreas Koczulla ,  Georg Degenfeld-Schonburg

IPC: A61K39/395 ,  A61K38/22 ,  A61K38/17 ,  A61K48/00 ,  A61K31/56

CPC classification number: A61K38/17 ,  A61K31/56

Abstract: A pharmaceutical composition containing a peptide or pharmaceutically acceptable salt thereof containing the amino acid sequence LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES (LL-37); for preventing or treating wounds, tumors, or disease caused by or resulting in a reduced level of angiogenesis or of arteriogenesis is disclosed.

Abstract translation: 含有含有氨基酸序列LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES（LL-37）的肽或其药学上可接受的盐的药物组合物; 公开了用于预防或治疗由血管生成或动脉生成降低引起或导致血管生成或血管发生水平降低的伤口，肿瘤或疾病。

公开(公告)号：US06399370B1

公开(公告)日：2002-06-04

申请号：US09228302

申请日：1999-01-12

Applicant: James M. Wilson ,  Mitchell Goldman ,  Robert Bals ,  Ethan D. Stolzenberg ,  Mark Anderson ,  Michael Zasloff ,  Prasad Kari

Inventor： James M. Wilson ,  Mitchell Goldman ,  Robert Bals ,  Ethan D. Stolzenberg ,  Mark Anderson ,  Michael Zasloff ,  Prasad Kari

IPC: C07H2100

CPC classification number: C07K14/4723 ,  A61K38/00

Abstract: The invention relates to mammalian beta defensin and methods of use thereof for treatment of microbial infection.

Abstract translation: 本发明涉及哺乳动物β防御素及其用于治疗微生物感染的方法。