Sustained release of guaifenesin
    1.
    发明授权
    Sustained release of guaifenesin 有权
    愈创甘油的持续释放

    公开(公告)号:US07838032B2

    公开(公告)日:2010-11-23

    申请号:US10406557

    申请日:2003-04-04

    IPC分类号: A61K9/22

    摘要: The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a water-insoluble polymer, preferably an acrylic resin, in a ratio range of about one-to-one (1:1) to about nine-to-one (9:1), more preferably a range of about three-to-two (3:2) to about six-to-one (6:1), and most preferably in a range of about two-to-one (2:1) to about four-to-one (4:1) by weight. This formulation capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject. The invention also relates to a modified release product which has two portions: a first portion having an immediate release formulation of guaifenesin and a second portion having a sustained release formulation of guaifenesin. The modified release product has a maximum guaifenesin serum concentration equivalent to that of an immediate release guaifenesin tablet, and is capable of providing therapeutically effective bioavailability of guaifenesin for at least twelve hours after dosing in a human subject.

    摘要翻译: 本发明涉及愈创甘油醚的新型药物缓释制剂。 制剂可包含亲水性聚合物,优选羟丙基甲基纤维素和水不溶性聚合物,优选丙烯酸树脂,其比例范围为约一对一(1:1)至约九对一(9 :1),更优选约三至二(3:2)至约六对一(6:1)的范围,最优选在约二至一(2:1)的范围内 )至约四对一(4:1)重量比。 该制剂能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。 本发明还涉及一种具有两部分的改良释放产物:第一部分具有愈创甘油醚的立即释放制剂,第二部分具有愈创甘油醚的缓释制剂。 改性释放产物具有与立即释放愈创甘油醚片剂相当的最大愈创甘油醚血清浓度,并且能够在给予人受试者后至少十二个小时提供愈创甘油的治疗有效的生物利用度。

    Round baler with semi-automatically sequenced operating cycles and selectively variable point of operator intervention
    2.
    发明授权
    Round baler with semi-automatically sequenced operating cycles and selectively variable point of operator intervention 有权
    圆形打捆机具有半自动排序的操作循环和选择性可变点的操作员干预

    公开(公告)号:US06675561B2

    公开(公告)日:2004-01-13

    申请号:US10330878

    申请日:2002-12-27

    IPC分类号: B65B1104

    摘要: A semi-automatic round baler having an “auto kick” or “auto wrap” mode. In the auto kick mode, at the conclusion of the forming cycle the baler will stop and await the operator's signal to continue. Once the operator has signaled to continue, the baler will wrap the bale and will immediately proceed to the ejecting cycle. In auto wrap mode, the baler will automatically enter into and complete the wrapping cycle (after a short delay) following completion of the forming cycle. At the conclusion of the wrapping cycle in the auto wrap mode, the baler will await the operator's signal before ejecting the completed bale.

    摘要翻译: 具有“自动踢”或“自动换行”模式的半自动圆打包机。 在自动起动模式下,在成型周期结束时,打包机将停止并等待操作者的信号继续。 一旦操作员发出信号,继续打包机将打包捆包,并将立即进入弹出循环。 在自动包装模式下,打包机将在完成成型周期后自动进入并完成包装周期(短时间后)。 在自动包装模式中的包装周期结束时,打包机将等待操作员的信号,然后弹出完成的捆包。

    Process for preparing quinoline bases
    4.
    发明授权
    Process for preparing quinoline bases 失效
    制备喹啉碱的方法

    公开(公告)号:US5700942A

    公开(公告)日:1997-12-23

    申请号:US678155

    申请日:1996-07-11

    IPC分类号: C07D215/04 C07D215/06

    CPC分类号: C07D215/06

    摘要: There are provided processes for preparing quinolines by vapor phase reaction of a substituted or unsubstituted aniline base, formaldehyde and a C.sub.2 -C.sub.4 aldehyde wherein the aldehydes:aniline base molar ratio is at least 2:1. More preferred processes of the invention achieve high selectivities and yields of 8-methylquinoline, and high conversions of the aniline base.

    摘要翻译: 提供了通过取代或未取代的苯胺基,甲醛和C 2 -C 4醛的气相反应制备喹啉的方法,其中醛:苯胺基摩尔比至少为2:1。 本发明的更优选的方法实现8-甲基喹啉的高选择性和产率,以及苯胺碱的高转化率。

    Tungsten alloys containing A15 structure and method for making same
    5.
    发明授权
    Tungsten alloys containing A15 structure and method for making same 失效
    含有A15结构的钨合金及其制造方法

    公开(公告)号:US4427445A

    公开(公告)日:1984-01-24

    申请号:US399201

    申请日:1982-07-21

    CPC分类号: C23C16/32

    摘要: A hard fine-grained internally stressed material of tungsten and carbon or tungsten, carbon and oxygen is described which is produced by thermochemical deposition. The material consists primarily of a two phase mixture of pure tungsten and an A15 structure, is free of columnar grain distribution, and has a hardness of greater than 1,200 VHN. The average grain size is less than 0.1 micron.

    摘要翻译: 描述了通过热化学沉积产生的钨和碳或钨,碳和氧的硬细颗粒内应力材料。 该材料主要由纯钨和A15结构的两相混合物组成,不含柱状晶粒分布,硬度大于1200HVN。 平均粒径小于0.1微米。

    Plasma method and apparatus for carrying out high temperature chemical
reactions
    6.
    发明授权
    Plasma method and apparatus for carrying out high temperature chemical reactions 失效
    用于进行高温化学反应的等离子体方法和装置

    公开(公告)号:US3954954A

    公开(公告)日:1976-05-04

    申请号:US430228

    申请日:1974-01-02

    摘要: In the process of carrying out high temperature, chemical reactions including reductions for producing elemental metal powders, especially refractory metals; chlorinations for producing halogens and for chemical synthesis in general using a plasma generator, the reactant or reactants feed material is introduced into the reaction zone of the apparatus and the effluent from the reaction zone is directed into a quenching zone through a selectively variable passageway or orifice in a manner that permits in the reduction process separation of the desired reaction product from the effluent hot gas stream and the continuous collection of the reaction product in a collection zone wherein in some instances, the reaction product is of a selected characteristic, controlled by the maintenance of certain operational parameters, including a selected differential fluid pressure in the reaction and collection zone as well as reaction and collection zone temperatures. Apparatus for carrying out the high temperature chemical reactions is disclosed.

    摘要翻译: 在进行高温化学反应的过程中,包括生产元素金属粉末,特别是难熔金属的减少; 通常使用等离子体发生器生产卤素和用于化学合成的氯化物,反应物或反应物进料被引入装置的反应区,来自反应区的流出物通过选择性可变的通道或孔口引入淬火区 以允许还原过程将期望的反应产物与流出的热气流分离并在反应产物在收集区中的连续收集,其中在某些情况下,反应产物具有选定的特征,由 维护某些操作参数,包括反应和收集区中选定的差分流体压力以及反应和收集区温度。 公开了用于进行高温化学反应的装置。

    Method and apparatus for developing balance information for rotating
equipments and assemblies
    7.
    发明授权
    Method and apparatus for developing balance information for rotating equipments and assemblies 失效
    用于开发旋转设备和组件的平衡信息的方法和装置

    公开(公告)号:US3939715A

    公开(公告)日:1976-02-24

    申请号:US482336

    申请日:1974-06-24

    申请人: Robert D. Davis

    发明人: Robert D. Davis

    IPC分类号: G01M1/22

    CPC分类号: G01M1/22

    摘要: A system for determining the phase displacement of vibration data signals relative to tachometer point signals by synthesizing a sine wave signal having the amplitude of the vibration data signals, shifting the phase of the synthesized sine wave signal to null out the vibration data signals and determining the phase and amplitude of the synthesized sine wave signal relative to the tachometer point signals.

    摘要翻译: 一种用于通过合成具有振动数据信号的振幅的正弦波信号来确定振动数据信号相对于转速计点信号的相位位移的系统,将合成的正弦波信号的相位移位,以消除振动数据信号,并确定 合成正弦波信号的相位和幅度相对于转速表点信号。

    Printer and method for controlling power consumption thereof
    8.
    发明授权
    Printer and method for controlling power consumption thereof 有权
    用于控制其功耗的打印机和方法

    公开(公告)号:US09033450B2

    公开(公告)日:2015-05-19

    申请号:US13275502

    申请日:2011-10-18

    IPC分类号: B41J29/393 B41J2/045

    摘要: A printer having an internal electrical power supply is disclosed herein. A method for controlling power consumption in the printer includes receiving an image to be printed, calculating an estimated temperature of the printer, and controlling a speed of the printer to control the power consumption to keep a temperature of the printer below a predetermined maximum temperature in response to the estimated temperature.

    摘要翻译: 本文公开了具有内部电源的打印机。 一种用于控制打印机中的功耗的方法,包括接收要打印的图像,计算打印机的估计温度,以及控制打印机的速度以控制打印机的温度低于预定最高温度的功率消耗 响应估计的温度。

    DC motor control
    9.
    发明授权
    DC motor control 有权
    直流电机控制

    公开(公告)号:US06674260B1

    公开(公告)日:2004-01-06

    申请号:US10175711

    申请日:2002-06-20

    IPC分类号: G05B1128

    摘要: A method of controlling a DC motor is presented. In a tracking action, an input to the motor is tracked. In a comparing action, the input is compared against a baseline value. In an adjusting action, a usage of the motor is adjusted when the input passes a threshold related to a motor performance parameter. A method of estimating a parameter of an ink carriage moved by a DC motor is also presented. In a tracking step, an input to the motor is tracked. In a comparing action, the input is compared against a baseline value to predict a level of the parameter.

    摘要翻译: 提出了一种控制直流电动机的方法。 在跟踪动作中,跟踪到电机的输入。 在比较动作中,将输入与基准值进行比较。 在调节动作中,当输入通过与电动机性能参数相关的阈值时,调节电动机的使用。 还提出了一种估计由DC电动机移动的墨盒的参数的方法。 在跟踪步骤中,跟踪到电动机的输入。 在比较动作中,将输入与基线值进行比较,以预测参数的水平。

    Dental flossing device
    10.
    发明授权
    Dental flossing device 失效
    牙线牙线器具

    公开(公告)号:US5060681A

    公开(公告)日:1991-10-29

    申请号:US632829

    申请日:1990-12-24

    IPC分类号: A61C15/04

    CPC分类号: A61C15/046

    摘要: An elongated handle with an internal supply of fresh dental floss and a flossing head including a fork provides oral hygiene. A fresh section of floss is advanced by a one-touch arrangement which concurrently relegates spent floss to a separate take-up reel. The fresh floss spanning the tines of the fork is kept taut at all times as a result of various special expedients including a differential spool and drum and a rack and pinion floss locking arrangement. When the supply of fresh floss on the bobbin is exhausted, the device is discarded.

    摘要翻译: 具有内部供应新鲜牙线的细长手柄和包括叉子的牙线头提供口腔卫生。 一个新鲜的牙线通过一个单一的方式推进,同时将花丝卷入单独的收卷卷轴。 由于各种特殊的使用方法,包括差速器卷轴和滚筒以及齿条和齿条的牙线锁定装置,跨越叉叉齿的新鲜牙线始终保持紧固。 当线筒上的新鲜牙线供应耗尽时,设备被丢弃。