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1.发明申请Peptides blocking vascular endothelial growth factor(vegf)-mediated angiogenesis, polynucleotides encoding said pepetides and methods of use thereof 审中-公开阻断血管内皮生长因子（vegf）介导的血管发生的肽，编码所述肽的多核苷酸及其使用方法公开(公告)号：US20050019826A1
公开(公告)日：2005-01-27
申请号：US10239211
申请日：2001-03-29
申请人： Roselyne Tournaire , Caroline Demangel , Claude Derbin , Gerard Perret , Jean-Claude Mazie , Jean Plouet , Roger Vassy
发明人： Roselyne Tournaire , Caroline Demangel , Claude Derbin , Gerard Perret , Jean-Claude Mazie , Jean Plouet , Roger Vassy
IPC分类号： C12N15/09 , A61K38/00 , A61K38/18 , A61P3/10 , A61P9/00 , A61P17/00 , A61P17/06 , A61P27/02 , A61P35/00 , C07K5/09 , C07K7/06 , C07K14/52 , C07K14/71 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , G01N33/53 , A61K38/17 , C07H21/04 , C07K14/47 , G01N33/543
CPC分类号： C07K7/06 , A61K38/00 , C07K5/0815 , C07K14/52 , C07K14/71 , G01N33/6845 , G01N33/74 , G01N2333/475
摘要： The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.
摘要翻译： 本发明提供可与VEGF相互作用并抑制VEGF与KDR或抗-VEGF抗体相互作用的肽，从而抑制VEGF介导的血管发生或血管新鲜相关疾病，编码肽的多核苷酸，含有多核苷酸的载体，含有该肽的药物组合物和 抑制肽的血管生成。
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2.发明授权Peptides blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis, polynucleotides encoding said peptides and methods of use thereof 失效肽阻断血管内皮生长因子（VEGF）介导的血管发生，编码所述肽的多核苷酸及其使用方法公开(公告)号：US06559126B2
公开(公告)日：2003-05-06
申请号：US09822270
申请日：2001-04-02
申请人： Roselyne Tournaire , Caroline Demangel , Claude Derbin , Gerard Perret , Jean-Claude Mazie , Jean Plouet , Roger Vassy
发明人： Roselyne Tournaire , Caroline Demangel , Claude Derbin , Gerard Perret , Jean-Claude Mazie , Jean Plouet , Roger Vassy
IPC分类号： A61K3800
CPC分类号： C07K7/06 , A61K38/00 , C07K5/0815 , C07K14/52 , C07K14/71 , G01N33/6845 , G01N33/74 , G01N2333/475
摘要： The present invention provides peptides which can interact with VEGF and inhibit VEGF interaction with KDR or anti-VEGF antibody thereby inhibiting VEGF mediated angiogenesis or angiogeneis related diseases, polynucleotide encoding the peptides, vectors containing the polynucleotides, pharmaceutical compositions containing the peptides, and methods of inhibiting angiogenesis with the peptides.
摘要翻译： 本发明提供可与VEGF相互作用并抑制VEGF与KDR或抗-VEGF抗体相互作用的肽，从而抑制VEGF介导的血管发生或血管新鲜相关疾病，编码肽的多核苷酸，含有多核苷酸的载体，含有该肽的药物组合物和 抑制肽的血管生成。
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