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1.
公开(公告)号:US20050214831A1
公开(公告)日:2005-09-29
申请号:US11050926
申请日:2005-02-04
申请人: John Monahan , Manjula Gannavarapu , Sebastian Hoersch , Shubhangi Kamatkar , Steven Kovats , Rachel Meyers , Michael Morrissey , Peter Olandt , Ami Sen , Petter Veiby , Gordon Mills , Robert Bast , Karen Lu , Rosemarie Schmandt , Xumei Zhao , Karen Glatt
发明人: John Monahan , Manjula Gannavarapu , Sebastian Hoersch , Shubhangi Kamatkar , Steven Kovats , Rachel Meyers , Michael Morrissey , Peter Olandt , Ami Sen , Petter Veiby , Gordon Mills , Robert Bast , Karen Lu , Rosemarie Schmandt , Xumei Zhao , Karen Glatt
IPC分类号: C12Q1/68 , G01N33/574
CPC分类号: C12Q1/6886 , C12Q2600/158
摘要: The invention relates to newly discovered nucleic acid molecules and proteins associated with ovarian cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human ovarian cancers are provided.
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2.
公开(公告)号:US20120070486A1
公开(公告)日:2012-03-22
申请号:US12526756
申请日:2008-02-12
IPC分类号: A61K9/127 , A61K31/7088 , A61K9/00 , A61P35/00 , A61K38/12 , A61K31/704 , A61K38/14 , C07H21/00 , C07H21/02 , A61K33/24
CPC分类号: C12N15/1135 , C12N15/113 , C12N2310/14
摘要: The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides methods for the delivery of a siNA (e.g., a siRNA) to a cell to modulate expression of a PFDN 1-6. These methods may be used to treat a disease, such as cancer.
摘要翻译: 本发明涉及分子生物学和药物递送领域。 在某些实施方案中,本发明提供了将siNA(例如siRNA)递送至细胞以调节PFDN1-6的表达的方法。 这些方法可用于治疗诸如癌症的疾病。
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