公开(公告)号：US20140106336A1

公开(公告)日：2014-04-17

申请号：US13992547

申请日：2011-12-07

申请人： Kent J. Voorhees ,  Christopher R. Cox ,  Roy R. Mondesire

发明人： Kent J. Voorhees ,  Christopher R. Cox ,  Roy R. Mondesire

IPC分类号： G01N33/569

CPC分类号： G01N33/56916 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0838 ,  B01L2400/0406 ,  B01L2400/043 ,  G01N33/54326 ,  G01N33/54366 ,  G01N33/56911 ,  G01N33/585

摘要： The present disclosure generally relates to systems, devices and methods for detecting magnetic-field-concentrated target analytes within a lateral flow capillary.

摘要翻译： 本公开一般涉及在侧流毛细管内检测磁场浓缩目标分析物的系统，装置和方法。

公开(公告)号：US06391569B1

公开(公告)日：2002-05-21

申请号：US08715628

申请日：1996-09-18

申请人： Robert B. Grieve ,  Glenn R. Frank ,  Roy R. Mondesire ,  James P. Porter ,  Nancy Wisnewski

发明人： Robert B. Grieve ,  Glenn R. Frank ,  Roy R. Mondesire ,  James P. Porter ,  Nancy Wisnewski

IPC分类号： G01N3353

CPC分类号： C07K14/4354 ,  G01N33/569 ,  G01N2333/4353

摘要： The present invention includes a method to detect D. immitis infection in a host animal using a D. immitis Di33 protein to detect anti-D. immitis Di33 antibodies in a bodily fluid of the animal. Also included is a method to detect D. immitis infection in a host animal using a D. immitis anti-Di33 protein to detect Di33 proteins in a bodily fluid of the animal. The present invention also relates to D. immitis detection kits that include either a Di33 protein or an anti-Di33 antibody; such kits also include a composition to detect an immunocomplex between the anti-Di33 antibody and D. immitis Di33 protein. The present invention also includes Di33 proteins, nucleic acid molecules encoding such proteins, as well as recombinant molecules and recombinant cells comprising such nucleic acid molecules, and anti-Di33 antibodies. Also included are methods to produce such proteins, nucleic acid molecules and antibodies.

摘要翻译： 本发明包括使用D.Imitmiti Di33蛋白检测宿主动物中的D. immitis感染以检测抗-D的方法。 immitis Di33抗体在动物的体液中。 还包括在宿主动物中使用D.emmitis抗-Di33蛋白检测动物体内的Di33蛋白的方法。 本发明还涉及包含Di33蛋白或抗-Di33抗体的D.IMIITIS检测试剂盒; 这样的试剂盒还包括用于检测抗Di33抗体和D.Imitmiti Di33蛋白之间的免疫复合物的组合物。 本发明还包括Di33蛋白，编码这种蛋白质的核酸分子，以及重组分子和包含这种核酸分子的重组细胞和抗Di33抗体。 还包括产生这种蛋白质，核酸分子和抗体的方法。