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公开(公告)号:US08969509B2
公开(公告)日:2015-03-03
申请号:US13378989
申请日:2010-06-25
申请人: Bin Liu , Chun Wang , Ruoyu Zhan , Glenn P. Bartholomew , Janice W. Hong , Jean M. Wheeler , Brent S. Gaylord
发明人: Bin Liu , Chun Wang , Ruoyu Zhan , Glenn P. Bartholomew , Janice W. Hong , Jean M. Wheeler , Brent S. Gaylord
CPC分类号: C08G61/02 , C08G2261/3142 , C08G2261/3422 , C08G2261/5222
摘要: The devices and method are provided for detecting labeled and label-free analytes, such as nucleic acids and proteins, employing conjugated cationic, anionic and neutral polymers. The analytes can be immobilized on a solid support material. The solid support material can be disposed in the pre-fabricated patterns on a substrate. The chemical structures of the polymers employed by the various embodiments of the present invention are described herein.
摘要翻译: 提供的装置和方法用于检测标记和无标记分析物,如核酸和蛋白质,使用共轭阳离子,阴离子和中性聚合物。 分析物可以固定在固体支持材料上。 固体支撑材料可以以衬底上的预制图案设置。 本文描述了由本发明的各种实施方案采用的聚合物的化学结构。
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公开(公告)号:US20120252986A1
公开(公告)日:2012-10-04
申请号:US13378989
申请日:2010-06-25
申请人: Bin Liu , Chun Wang , Ruoyu Zhan , Glenn P. Bartholomew , Janice W. Hong , Jean M. Wheeler , Brent S. Gaylord
发明人: Bin Liu , Chun Wang , Ruoyu Zhan , Glenn P. Bartholomew , Janice W. Hong , Jean M. Wheeler , Brent S. Gaylord
IPC分类号: C08G65/00
CPC分类号: C08G61/02 , C08G2261/3142 , C08G2261/3422 , C08G2261/5222
摘要: The devices and method are provided for detecting labeled and label-free analytes, such as nucleic acids and proteins, employing conjugated cationic, anionic and neutral polymers. The analytes can be immobilized on a solid support material. The solid support material can be disposed in the pre-fabricated patterns on a substrate. The chemical structures of the polymers employed by the various embodiments of the present invention are described herein.
摘要翻译: 提供的装置和方法用于检测标记和无标记分析物,如核酸和蛋白质,使用共轭阳离子,阴离子和中性聚合物。 分析物可以固定在固体支持材料上。 固体支撑材料可以以衬底上的预制图案设置。 本文描述了由本发明的各种实施方案采用的聚合物的化学结构。
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