公开(公告)号：US20070231785A1

公开(公告)日：2007-10-04

申请号：US11397958

申请日：2006-04-04

申请人： Clifford Hoyt ,  Peter Harvey ,  Russell Gershman

发明人： Clifford Hoyt ,  Peter Harvey ,  Russell Gershman

IPC分类号： C12Q1/00 ,  G06T7/40

CPC分类号： G01N21/23

摘要： Disclosed are methods and systems for microscope imaging that involve positioning a biological sample within a field of view of a microscope having an optical axis, and rotating the biological sample about a rotation axis different from the optical axis to improve an image of the sample produced by the microscope. The methods and systems are especially useful in assisted reproductive technologies, for example, to assess the developmental potential of oocytes.

摘要翻译： 公开了用于显微镜成像的方法和系统，其涉及将生物样品定位在具有光轴的显微镜的视野内，并且围绕不同于光轴的旋转轴旋转生物样品，以改善生物样品由 显微镜。 方法和系统在辅助生殖技术中尤其有用，例如评估卵母细胞的发育潜力。

公开(公告)号：US5793969A

公开(公告)日：1998-08-11

申请号：US585183

申请日：1996-01-11

申请人： Louis A. Kamentsky ,  Mark Weissman ,  Lee D. Kamentsky ,  Russell Gershman ,  B. Martin Pomeroy

发明人： Louis A. Kamentsky ,  Mark Weissman ,  Lee D. Kamentsky ,  Russell Gershman ,  B. Martin Pomeroy

IPC分类号： G01N1/28 ,  G02B21/26 ,  G02B21/34 ,  G06F19/00 ,  H04L12/00 ,  G06K9/00 ,  G06F13/00

CPC分类号： G01N1/2813 ,  G02B21/26 ,  G02B21/34 ,  G06F19/321 ,  G06F19/366 ,  G01N2001/282

摘要： A network system for review and analysis of computer encoded microscope slides and specimens which were originally computer encoded from a microscope (attached via an encoder device to a local computer site), during an initial examination. The encoding includes parameters of viewing locations and events of interest on the slide, with such information being stored on a networked file server. The encoding also includes information regarding the manner in which the initial examination was conducted, for quality control purposes. The computer encoded information is retrievable at all remote locations of the network (either local or connected via modem) for supervisor review or for pathologist analysis. The network is further constituted by microscope sites having similar computer encoding devices attached thereto, which function, in this aspect, as computer terminals of the network. For enhanced analysis, the computer terminals have direct access to patient background information, e.g., such as from an HIS (hospital information system) for simultaneous slide analysis review in relation to the medical history of the patient. For diagnostic support, the computer terminals are networked with an on-line library of cell type images for comparison with the slide being examined. Slide diagnosis is either directly with the original slide on the microscope or with a scanned image of the slide stored in the network server or CD-ROM and retrieved on the computer terminal. The microscope is optionally motor driven, with computer control, to re-scan slides or slide images only at designated sites.

摘要翻译： 在初次检查期间，用于检查和分析计算机编码的显微镜载玻片和标本的网络系统，其最初由计算机从显微镜编码（通过编码器装置附接到本地计算机站点）进行编码。 编码包括在幻灯片上观看位置和感兴趣的事件的参数，其中这些信息被存储在联网的文件服务器上。 编码还包括关于进行初步检查的方式的信息，用于质量控制目的。 计算机编码的信息可以在网络的所有远程位置（本地或通过调制解调器连接）检索，以供主管审查或用于病理学家分析。 该网络由具有附接到其上的类似计算机编码装置的显微镜站点进一步构成，在该方面，其作为网络的计算机终端。 为了增强分析，计算机终端可以直接访问患者背景信息，例如来自HIS（医院信息系统），用于与病人的病史有关的同时幻灯片分析审查。 对于诊断支持，计算机终端与网络图像的网格库联网，以便与被检查的幻灯片进行比较。 幻灯片诊断直接与显微镜上的原始幻灯片或存储在网络服务器或CD-ROM中的幻灯片的扫描图像并在计算机终端上检索。 显微镜可选择由电机驱动，具有电脑控制功能，只能在指定的位置重新扫描幻灯片或幻灯片图像。