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公开(公告)号:US4666249A
公开(公告)日:1987-05-19
申请号:US765891
申请日:1985-08-14
申请人: Robert E. Bauman , S. Kumar Chandrasekaran , Shaow B. Lin , Lyle M. Bowman , Thomas B. Harvey, III
发明人: Robert E. Bauman , S. Kumar Chandrasekaran , Shaow B. Lin , Lyle M. Bowman , Thomas B. Harvey, III
摘要: A contact lens for correction of astigmatism is formed from a single polymeric or copolymeric material. The lens has a central optical zone of greater rigidity than a surrounding non-optical zone. The rigidity of the central optical zone is sufficient for it to retain an astigmatism-correcting shape when worn on an eye, while the surrounding non-optical zone conforms to the shape of the eye.
摘要翻译: 用于矫正散光的隐形眼镜由单一聚合物或共聚物材料形成。 透镜具有比周围的非光学区域更大的刚性的中心光学区域。 中心光学区域的刚度足以使其佩戴在眼睛上时保持像散矫正形状,而周围的非光学区域符合眼睛的形状。
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公开(公告)号:US07795231B2
公开(公告)日:2010-09-14
申请号:US11905854
申请日:2007-10-04
IPC分类号: A61K31/00
CPC分类号: A61K9/0048 , A61K9/0014 , A61K9/0034 , A61K9/0043 , A61K9/0046 , A61K9/0051 , A61K9/0056 , A61K9/0058 , A61K9/0063 , A61K9/0078 , A61K9/008 , A61K31/00 , A61K31/351 , A61K31/573 , A61K31/7052 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要: The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amount of a concentrated aqueous azalide antibiotic formulation made according to the method comprising dissolving an azalide antibiotic in an aqueous solution comprising a strong acid. The invention also relates to methods for making concentrated aqueous azalide antibiotic formulations for use in pulmonary infection, a nasopharyngeal infection, an otic infection, an ocular infection, a dermal or a vaginal infection. The invention also relates to concentrated aqueous azalide antibiotic formulations made by dissolving an azalide antibiotic in an aqueous solution comprising a strong acid.
摘要翻译: 本发明涉及浓氮ide啶抗生素的制剂及其制备和使用方法。 具体地说,本发明涉及一种治疗感染的方法,其包括对有需要的患者施用有效量的根据包括将含有强酸的水溶液中的氮杂抗生素溶解的方法制备的浓氮唑类抗生素制剂。 本发明还涉及用于制备用于肺部感染,鼻咽感染,耳部感染,眼部感染,皮肤或阴道感染的浓盐酸阿糖苷类抗生素制剂的方法。 本发明还涉及通过将azalide抗生素溶解在包含强酸的水溶液中制备的浓氮唑类抗生素制剂。
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公开(公告)号:US4687816A
公开(公告)日:1987-08-18
申请号:US765886
申请日:1985-08-14
CPC分类号: C08J7/14 , G02B1/043 , C08J2333/14
摘要: A process for the treatment of a soft contact lens, to increase its resistance to the deposition thereon and diffusion and accumulation therein of substances which will promote its clouding and discoloration in use, and to improve its mechanical strength, includes treating a hydroxyl group-containing acrylic ester soft contact lens or replica with an organic acid anhydride for a sufficient period of time to treat at least a portion of polymer molecules on the outer surfaces, e.g. by esterifying hydroxyl groups on the molecules and facilitating extraction of organic-type impurities. The process is optionally performed in the presence of a medium which partially swells the surface regions of the lens or replica prior to or during the process.
摘要翻译: 一种用于治疗软性隐形眼镜的方法,以增加其对其上的沉积的抵抗力,并且在其中扩散和积累将促进其在使用中的浑浊和变色并且提高其机械强度的物质包括处理含羟基的 丙烯酸酯软性隐形眼镜或有机酸酐复制足够的时间以处理外表面上的至少一部分聚合物分子,例如 通过酯化分子上的羟基并促进有机型杂质的萃取。 该方法任选地在介质之前或之后部分溶胀透镜或复制品的表面区域的介质的存在下进行。
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公开(公告)号:US20100305054A1
公开(公告)日:2010-12-02
申请号:US12855096
申请日:2010-08-12
IPC分类号: A61K31/7052 , A61P33/02 , A61P31/04 , A61P29/00
CPC分类号: A61K9/0048 , A61K9/0014 , A61K9/0034 , A61K9/0043 , A61K9/0046 , A61K9/0051 , A61K9/0056 , A61K9/0058 , A61K9/0063 , A61K9/0078 , A61K9/008 , A61K31/00 , A61K31/351 , A61K31/573 , A61K31/7052 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要: The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amount of a concentrated aqueous azalide antibiotic formulation made according to the method comprising dissolving an azalide antibiotic in an aqueous solution comprising a strong acid. The invention also relates to methods for making concentrated aqueous azalide antibiotic formulations for use in pulmonary infection, a nasopharyngeal infection, an otic infection, an ocular infection, a dermal or a vaginal infection. The invention also relates to concentrated aqueous azalide antibiotic formulations made by dissolving an azalide antibiotic in an aqueous solution comprising a strong acid.
摘要翻译: 本发明涉及浓氮ide啶抗生素的制剂及其制备和使用方法。 具体地说,本发明涉及一种治疗感染的方法,其包括对有需要的患者施用有效量的根据包括将含有强酸的水溶液中的氮杂抗生素溶解的方法制备的浓氮唑类抗生素制剂。 本发明还涉及用于制备用于肺部感染,鼻咽感染,耳部感染,眼部感染,皮肤或阴道感染的浓盐酸阿糖苷类抗生素制剂的方法。 本发明还涉及通过将azalide抗生素溶解在包含强酸的水溶液中制备的浓氮唑类抗生素制剂。
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公开(公告)号:US20090093449A1
公开(公告)日:2009-04-09
申请号:US11905854
申请日:2007-10-04
IPC分类号: A61K31/351 , A61K31/573 , A61P31/04
CPC分类号: A61K9/0048 , A61K9/0014 , A61K9/0034 , A61K9/0043 , A61K9/0046 , A61K9/0051 , A61K9/0056 , A61K9/0058 , A61K9/0063 , A61K9/0078 , A61K9/008 , A61K31/00 , A61K31/351 , A61K31/573 , A61K31/7052 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/38 , A61K2300/00
摘要: The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amount of a concentrated aqueous azalide antibiotic formulation made according to the method comprising dissolving an azalide antibiotic in an aqueous solution comprising a strong acid. The invention also relates to methods for making concentrated aqueous azalide antibiotic formulations for use in pulmonary infection, a nasopharyngeal infection, an otic infection, an ocular infection, a dermal or a vaginal infection. The invention also relates to concentrated aqueous azalide antibiotic formulations made by dissolving an azalide antibiotic in an aqueous solution comprising a strong acid.
摘要翻译: 本发明涉及浓氮ide啶抗生素的制剂及其制备和使用方法。 具体地说,本发明涉及一种治疗感染的方法,其包括对有需要的患者施用有效量的根据包括将含有强酸的水溶液中的氮杂抗生素溶解的方法制备的浓氮唑类抗生素制剂。 本发明还涉及用于制备用于肺部感染,鼻咽感染,耳部感染,眼部感染,皮肤或阴道感染的浓盐酸阿糖苷类抗生素制剂的方法。 本发明还涉及通过将azalide抗生素溶解在包含强酸的水溶液中制备的浓氮唑类抗生素制剂。
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