中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

20 records (took 0.016 seconds)

    Methods for treating ocular inflammatory diseases
    1.
    发明授权
    Methods for treating ocular inflammatory diseases 有权

    公开(公告)号：US10201548B2

    公开(公告)日：2019-02-12

    申请号：US12399729

    申请日：2009-03-06

    Applicant: Lyle Bowman ,  Kamran Hosseini

    Inventor： Lyle Bowman ,  Kamran Hosseini

    IPC: A61K31/56

    Abstract: A method of treating blepharitis includes administering to the affected eye of a subject an effective amount of an active ingredient in an ophthalmically acceptable vehicle for a sufficient period of time to treat blepharitis. The active ingredient consists essentially of a glucocorticoid in an ophthalmically acceptable vehicle that includes an aqueous polymer suspension that when mixed with tear fluid provides a sustained release of said active ingredient. The aqueous polymer suspension includes a carboxyl-containing polymer having less than about 5% by weight cross-linking agent and has a viscosity in a range from about 1,000 to about 30,000 centipoises. A kit includes: (a) a composition comprising about 0.1% by weight dexamethasone in this ophthalmically acceptable vehicle and (b) instructions for using the composition of (a) for the treatment of blepharitis.

    Drug delivery system and methods of use
    3.
    发明授权
    Drug delivery system and methods of use 有权
    药物输送系统及使用方法

    公开(公告)号：US08083347B2

    公开(公告)日：2011-12-27

    申请号：US12416802

    申请日：2009-04-01

    Applicant: Joseph J. Bango, Jr. ,  Lyle Bowman ,  Gary Wnek ,  Shachar Tauber ,  Randall Fuerst

    Inventor： Joseph J. Bango, Jr. ,  Lyle Bowman ,  Gary Wnek ,  Shachar Tauber ,  Randall Fuerst

    IPC: G02C7/04 ,  G02C7/02 ,  A61K9/00

    CPC classification number: B29D11/00048 ,  A61K9/0051 ,  A61K9/0092

    Abstract: Electrospun fibers are utilized to improve the mechanical characteristics of a contact lens reducing the weight and mechanical strength of the polymers from which the lenses are typically formed. Electrospun fibers are also utilized as a drug delivery system, both through direct use in the eye and by inclusion of the fibers in a contact lens. The fibers are loaded with therapeutic drugs by a variety of methods and processed by coating and cross-linking the fibers.

    Abstract translation: 电纺纤维用于改善隐形眼镜的机械特性，降低通常形成透镜的聚合物的重量和机械强度。 电纺纤维也被用作药物递送系统，通过直接使用在眼睛中并通过将纤维包含在隐形眼镜中。 纤维通过各种方法装载治疗药物并通过涂布和交联纤维进行加工。

    TIP ARRANGEMENT FOR A DROPPER BOTTLE
    5.
    发明申请
    TIP ARRANGEMENT FOR A DROPPER BOTTLE 有权
    蘸水瓶的提示布置

    公开(公告)号：US20100224657A1

    公开(公告)日：2010-09-09

    申请号：US12399596

    申请日：2009-03-06

    Applicant: Lyle Bowman

    Inventor： Lyle Bowman

    IPC: B65D47/18 ,  B65D25/48 ,  B65D83/00

    CPC classification number: B65D47/18 ,  A61F9/0008 ,  B65D25/48

    Abstract: A tip arrangement for a bottle used for dispensing viscous liquid, such as drops of medicine, is provided. Embodiments include a tip insert having an insert body and a piercing point at a lower end of the insert body, for piercing a top surface of the bottle and for retaining the tip insert on the top surface of the bottle after piercing. A passage extends from a distal end of the piercing point, through the insert body, to an opposing upper surface of the insert body. A dispensing tip at the insert body upper surface communicates with the passage for precisely forming drops of the liquid from the bottle.

    Abstract translation: 提供了用于分配粘性液体的瓶子的尖端装置，例如药液滴。 实施例包括具有插入体和在插入体的下端处的刺穿点的尖端插入件，用于刺穿瓶子的顶部表面并且用于在刺穿之后将尖端插入物保持在瓶子的顶部表面上。 通道从穿刺点的远端穿过插入体延伸到插入体的相对的上表面。 插入体上表面的分配尖端与通道连通，用于从瓶中精确地形成液体液滴。

    Tip arrangement for a dropper bottle
    6.
    发明授权
    Tip arrangement for a dropper bottle 有权
    滴管瓶的提示布置

    公开(公告)号：US08695850B2

    公开(公告)日：2014-04-15

    申请号：US12399596

    申请日：2009-03-06

    Applicant: Lyle Bowman ,  Surendra Patel

    Inventor： Lyle Bowman ,  Surendra Patel

    IPC: B67D1/00 ,  B65D47/18

    CPC classification number: B65D47/18 ,  A61F9/0008 ,  B65D25/48

    Abstract: A tip arrangement for a bottle used for dispensing viscous liquid, such as drops of medicine, is provided. Embodiments include a tip insert having an insert body and a piercing point at a lower end of the insert body, for piercing a top surface of the bottle and for retaining the tip insert on the top surface of the bottle after piercing. A passage extends from a distal end of the piercing point, through the insert body, to an opposing upper surface of the insert body. A dispensing tip at the insert body upper surface communicates with the passage for precisely forming drops of the liquid from the bottle.

    Abstract translation: 提供了用于分配粘性液体的瓶子的尖端装置，例如药液滴。 实施例包括具有插入体和在插入体的下端处的刺穿点的尖端插入件，用于刺穿瓶子的顶部表面并且用于在刺穿之后将尖端插入物保持在瓶子的顶部表面上。 通道从穿刺点的远端穿过插入体延伸到插入体的相对的上表面。 插入体上表面的分配尖端与通道连通，用于从瓶中精确地形成液体液滴。

    Drug delivery system and methods of use
    7.
    发明授权
    Drug delivery system and methods of use 有权
    药物输送系统及使用方法

    公开(公告)号：US08361492B2

    公开(公告)日：2013-01-29

    申请号：US12490972

    申请日：2009-06-24

    Applicant: Shachar Tauber ,  Randall Fuerst ,  Keela Davis ,  Lyle Bowman ,  Gary Wnek ,  Joseph J. Bango, Jr.

    Inventor： Shachar Tauber ,  Randall Fuerst ,  Keela Davis ,  Lyle Bowman ,  Gary Wnek ,  Joseph J. Bango, Jr.

    IPC: A61F13/00 ,  A61K9/00

    CPC classification number: A61K9/0051 ,  A61K9/0092

    Abstract: Electrospun fibers are utilized to improve the mechanical characteristics of a contact lens reducing the weight and mechanical strength of the polymers from which the lenses are typically formed. Electrospun fibers are also utilized as a drug delivery system, both through direct use in the eye and by inclusion of the fibers in a contact lens. The fibers are loaded with therapeutic drugs by a variety of methods and processed by coating and cross-linking the fibers.

    Abstract translation: 电纺纤维用于改善隐形眼镜的机械特性，降低通常形成透镜的聚合物的重量和机械强度。 电纺纤维也被用作药物递送系统，通过直接使用在眼睛中并通过将纤维包含在隐形眼镜中。 纤维通过各种方法装载治疗药物并通过涂布和交联纤维进行加工。

    Controlled-release ophthalmic vehicles
    10.
    发明授权
    Controlled-release ophthalmic vehicles 有权
    控制释放眼科车辆

    公开(公告)号：US08501800B2

    公开(公告)日：2013-08-06

    申请号：US12398625

    申请日：2009-03-05

    Applicant: Lyle Bowman ,  Stephen Pham

    Inventor： Lyle Bowman ,  Stephen Pham

    IPC: A61K38/00 ,  A61K38/28 ,  A61K31/40

    CPC classification number: A61K9/0048 ,  A61K47/32 ,  A61K47/34 ,  A61K47/36

    Abstract: An ophthalmically acceptable vehicle includes an aqueous suspension having a first viscosity. The suspension includes about 0.1% to about 6.5% by weight of a carboxyl-containing polymer prepared by polymerizing one or more carboxyl-containing monoethylenically unsaturated monomers and less than about 5% by weight of a cross-linking agent. The polymer has average particle size of not more than about 50 μm in equivalent spherical diameter. The vehicle includes a second polymer that allows the carboxyl-containing polymer to remain suspended. Upon contact with tear fluid, the vehicle gels to a second viscosity which is greater than the first viscosity. A method of administering a medicament to the eye of a subject includes applying a composition that includes this ophthalmically acceptable vehicle and a medicament contained for treatment of a disease or disorder for which ophthalmic delivery is indicated. The medicament is released from the vehicle in a sustained release manner.

    Abstract translation: 眼科可接受的载体包括具有第一粘度的水性悬浮液。 悬浮液包含约0.1％至约6.5％重量的通过聚合一种或多种含羧基的单烯属不饱和单体和少于约5％重量的交联剂制备的含羧基聚合物。 该聚合物的平均粒径在等于球形直径的范围内不超过约50μm。 载体包括允许含羧基聚合物保持悬浮的第二聚合物。 当与泪液接触时，车辆凝胶化到比第一粘度大的第二粘度。 向受试者的眼睛施用药物的方法包括施用包含该眼科可接受载体的组合物和用于治疗指示眼科递送的疾病或病症的药物。 药物以持续释放的方式从车辆释放。

Patent Agency Ranking