公开(公告)号：US20230355564A1

公开(公告)日：2023-11-09

申请号：US18199797

申请日：2023-05-19

Applicant: SCF PHARMA INC.

Inventor： Samuel C. FORTIN

IPC: A61K31/232 ,  A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K35/60

CPC classification number: A61K31/232 ,  A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K35/60 ,  A61K36/185

Abstract: There are provided compositions comprising at least one compound chosenfrom compound of formula (I), compound of formula (II), compound of formula (III) and compound of formula (IV):




and a cannabinoid extract.

公开(公告)号：US11478443B2

公开(公告)日：2022-10-25

申请号：US16910055

申请日：2020-06-23

Applicant: SCF PHARMA INC.

Inventor： Samuel C. Fortin

IPC: A61K36/00 ,  A61K31/232 ,  A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K35/60 ,  A61K36/185

Abstract: There are provided various compositions comprising monoglyceride(s), diglyceride(s) and cannabinoid(s). These compositions can be useful for increasing the life span of a subject; for increasing the disability-free life expectancy, for slowing down the ageing process of a subject; for increasing the mitochondrial OXPHOS of a subject; for decreasing the mitochondrial LEAK of a subject; for increasing the mitochondrial RCR or COUPLING EFFICIENCY of a subject; and for optimizing the mitochondrial functions of a subject.

公开(公告)号：US09480660B2

公开(公告)日：2016-11-01

申请号：US14533641

申请日：2014-11-05

Applicant: SCF PHARMA INC.

Inventor： Samuel Fortin

IPC: A61K31/20 ,  A61K31/047 ,  A61K31/12 ,  A61K31/122 ,  A61K36/02 ,  A61K36/282 ,  A61K36/30 ,  A61K36/48 ,  A61K36/52 ,  A61K36/55 ,  A61K36/9066 ,  A61K47/14 ,  A61K31/232 ,  A61K31/23 ,  A61K31/202 ,  A61K9/127

CPC classification number: A61K31/232 ,  A61K9/127 ,  A61K31/047 ,  A61K31/12 ,  A61K31/122 ,  A61K31/20 ,  A61K31/202 ,  A61K31/23 ,  A61K36/02 ,  A61K36/282 ,  A61K36/30 ,  A61K36/48 ,  A61K36/52 ,  A61K36/55 ,  A61K36/9066 ,  A61K47/14 ,  Y02A50/463 ,  A61K2300/00

Abstract: There are provided methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing spondylitis and rheumatism. The method comprise administering to a subject in need thereof an effective amount of at least one lipid and an effective amount of at least one compound chosen from compounds of the present disclosure. Such compounds are polyunsaturated fatty acid monoglycerides or derivatives thereof.

Abstract translation: 提供了治疗炎症性疾病，哮喘，急性呼吸窘迫综合征，慢性阻塞性肺病，急性肺损伤，支气管肺发育不良，囊性纤维化，支气管炎，细支气管炎，关节炎，骨关节炎，强直性脊柱炎和风湿病等炎性疾病的方法。 该方法包括向有需要的受试者施用有效量的至少一种脂质和有效量的至少一种选自本发明化合物的化合物。 这些化合物是多不饱和脂肪酸单甘油酯或其衍生物。

公开(公告)号：US20220331283A1

公开(公告)日：2022-10-20

申请号：US17852060

申请日：2022-06-28

Applicant: SCF PHARMA INC.

Inventor： Samuel C. FORTIN

IPC: A61K31/232 ,  A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K35/60

Abstract: There are provided various compositions comprising monoglyceride(s) and cannabinoid(s). These compositions can be useful for increasing the life span of a subject; for increasing the disability-free life expectancy, for slowing down the ageing process of a subject; for increasing the mitochondrial OXPHOS of a subject; for decreasing the mitochondrial LEAK of a subject; for increasing the mitochondrial RCR or COUPLING EFFICIENCY of a subject; and for optimizing the mitochondrial functions of a subject.

公开(公告)号：US20170014369A1

公开(公告)日：2017-01-19

申请号：US15281240

申请日：2016-09-30

Applicant: SCF PHARMA INC.

Inventor： Samuel FORTIN

IPC: A61K31/232

CPC classification number: A61K31/232 ,  A61K9/127 ,  A61K31/047 ,  A61K31/12 ,  A61K31/122 ,  A61K31/20 ,  A61K31/202 ,  A61K31/23 ,  A61K36/02 ,  A61K36/282 ,  A61K36/30 ,  A61K36/48 ,  A61K36/52 ,  A61K36/55 ,  A61K36/9066 ,  A61K47/14 ,  Y02A50/463 ,  A61K2300/00

Abstract: There are provided compositions comprising Such compositions can also further comprise various components such as lipids (for example fatty acids, esters thereof or derivatives thereof). Such compositions can be used for example in methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing spondylitis and rheumatism.

Abstract translation: 这样的组合物还可以进一步包含各种组分如脂质（例如脂肪酸，其酯或其衍生物）。 这些组合物可用于治疗炎症性疾病，哮喘，急性呼吸窘迫综合征，慢性阻塞性肺病，急性肺损伤，支气管肺发育不良，囊性纤维化，支气管炎，细支气管炎，关节炎，骨关节炎， 强直性脊柱炎和风湿病。

公开(公告)号：US20150119591A1

公开(公告)日：2015-04-30

申请号：US14525621

申请日：2014-10-28

Applicant: SCF PHARMA INC.

Inventor： Samuel C. FORTIN

IPC: C07C69/732 ,  C07D303/16

CPC classification number: C07C69/732 ,  C07D303/16

Abstract: There are provided compounds of formula (I): wherein X1 is O, NH, or S; X2 is O, NH, or S; and X3 is O, NH, or S; and wherein R, R1, T1 and T2 can represent various entities. Such compounds can be useful, for example, for preventing, palliating or treating various diseases such as heart diseases, respiratory diseases, treating inflammatory abnormalities, metabolic disorders or diabetes.

Abstract translation: 提供式（I）化合物：其中X 1是O，NH或S; X2是O，NH或S; X3为O，NH或S; 并且其中R，R1，T1和T2可以表示各种实体。 这样的化合物可用于例如预防，缓解或治疗各种疾病如心脏病，呼吸系统疾病，治疗炎性异常，代谢紊乱或糖尿病。

公开(公告)号：US20220133676A1

公开(公告)日：2022-05-05

申请号：US17269253

申请日：2020-07-21

Applicant: SCF PHARMA INC.

Inventor： Samuel C. FORTIN

IPC: A61K31/232 ,  A61K31/05 ,  A61K31/192 ,  A61K31/352 ,  A61K35/60

Abstract: There are provided compositions comprising at least one compound chosen from compound of formula (I), compound of formula (II), compound of formula (III) and compound of formula (IV): and a cannabinoid extract.

公开(公告)号：US09925165B2

公开(公告)日：2018-03-27

申请号：US15281240

申请日：2016-09-30

Applicant: SCF PHARMA INC.

Inventor： Samuel Fortin

IPC: A61K31/20 ,  A61K31/232 ,  A61K31/047 ,  A61K31/12 ,  A61K31/122 ,  A61K36/02 ,  A61K36/282 ,  A61K36/30 ,  A61K36/48 ,  A61K36/52 ,  A61K36/55 ,  A61K36/9066 ,  A61K47/14 ,  A61K31/23 ,  A61K31/202 ,  A61K9/127

CPC classification number: A61K31/232 ,  A61K9/127 ,  A61K31/047 ,  A61K31/12 ,  A61K31/122 ,  A61K31/20 ,  A61K31/202 ,  A61K31/23 ,  A61K36/02 ,  A61K36/282 ,  A61K36/30 ,  A61K36/48 ,  A61K36/52 ,  A61K36/55 ,  A61K36/9066 ,  A61K47/14 ,  Y02A50/463 ,  A61K2300/00

Abstract: There are provided compositions comprising Such compositions can also further comprise various components such as lipids (for example fatty acids, esters thereof or derivatives thereof). Such compositions can be used for example in methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing spondylitis and rheumatism.

公开(公告)号：US20140296344A1

公开(公告)日：2014-10-02

申请号：US14303641

申请日：2014-06-13

Applicant: SCF PHARMA INC.

Inventor： Samuel FORTIN

IPC: C07C233/38

CPC classification number: C07C233/38 ,  C07C69/587 ,  C07C219/08 ,  C07C233/20 ,  C07D317/24 ,  C07D327/10 ,  C07F9/091 ,  C07F9/65742

Abstract: There are provided various polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds can be useful as cancer chemopreventive agents, cancer treating agent, inhibiting tumor growth or cell proliferation, reducing tumor growth or as radioenhencers for radiotherapy of cancer.

Abstract translation: 提供了各种多不饱和脂肪酸单甘油酯及其衍生物。 这些化合物可用作癌症化学预防剂，癌症治疗剂，抑制肿瘤生长或细胞增殖，减少肿瘤生长或作为癌症放射治疗剂的放射线剂。

公开(公告)号：US20250108028A1

公开(公告)日：2025-04-03

申请号：US18725239

申请日：2022-12-07

Applicant: SCF PHARMA INC.

Inventor： Samuel C. Fortin

IPC: A61K31/232 ,  A61K31/353 ,  A61K45/06 ,  A61P39/00

Abstract: There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful for use in cellular senescence prevention in a subject in need thereof or for slowing/delaying cellular senescence in a subject in need thereof. These compounds and compositions comprise at least one compound chosen from