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公开(公告)号：US20220386966A1
公开(公告)日：2022-12-08
申请号：US17742741
申请日：2022-05-12
发明人： Gregory J. Spangler
IPC分类号： A61B5/00 , G16H50/30 , G16H40/60 , A61B5/349 , G01N33/574 , A61B5/318 , G01N33/53 , G01N33/68 , G16H50/50 , A61B5/316 , A61B5/363
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
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公开(公告)号：US11331049B2
公开(公告)日：2022-05-17
申请号：US16947899
申请日：2020-08-24
发明人： Gregory J. Spangler
IPC分类号： A61B5/00 , G01N33/68 , G01N33/53 , G01N33/574 , G16H40/60 , G16H50/30 , G16H50/50 , A61B5/316 , A61B5/318 , A61B5/349 , A61B5/363
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
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公开(公告)号：US11045135B2
公开(公告)日：2021-06-29
申请号：US16261248
申请日：2019-01-29
发明人： Gregory J. Spangler
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
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公开(公告)号：US20180249965A1
公开(公告)日：2018-09-06
申请号：US15759386
申请日：2016-09-13
IPC分类号： A61B5/00 , A61B5/0402 , A61B5/04
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
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公开(公告)号：US20210378576A1
公开(公告)日：2021-12-09
申请号：US17350381
申请日：2021-06-17
发明人： Gregory J. Spangler
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
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公开(公告)号：US20190150769A1
公开(公告)日：2019-05-23
申请号：US16261248
申请日：2019-01-29
发明人： Gregory J. SPANGLER
IPC分类号： A61B5/04 , A61B5/046 , A61B5/00 , G06K9/00 , A61B5/0402
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
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公开(公告)号：US20240245362A1
公开(公告)日：2024-07-25
申请号：US18521410
申请日：2023-11-28
发明人： Gregory J. Spangler
CPC分类号： A61B5/7275 , A61B5/346 , A61B5/361 , A61B5/7207 , A61B5/7246 , A61B5/7267 , A61B5/7405 , A61B5/742 , A61B5/7455 , A61B5/7475 , A61B5/282 , A61B5/7203 , A61B5/725 , A61B2562/221 , G06F2218/16
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
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公开(公告)号：US20210128072A1
公开(公告)日：2021-05-06
申请号：US16947899
申请日：2020-08-24
发明人： Gregory J. SPANGLER
IPC分类号： A61B5/00 , G01N33/68 , G01N33/53 , G01N33/574 , G16H40/60 , G16H50/30 , G16H50/50 , A61B5/316 , A61B5/318 , A61B5/349 , A61B5/363
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
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公开(公告)号：US10226196B2
公开(公告)日：2019-03-12
申请号：US15693730
申请日：2017-09-01
发明人： Gregory J. Spangler
IPC分类号： A61B5/04 , A61B5/00 , A61B5/0402 , G06K9/00 , A61B5/046 , G06F19/00 , A61B5/0408
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
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公开(公告)号：US20170367604A1
公开(公告)日：2017-12-28
申请号：US15693730
申请日：2017-09-01
发明人： Gregory J. Spangler
IPC分类号： A61B5/04 , A61B5/00 , A61B5/0402 , G06K9/00
CPC分类号： A61B5/04017 , A61B5/04012 , A61B5/0402 , A61B5/04085 , A61B5/046 , A61B5/7203 , A61B5/7207 , A61B5/7246 , A61B5/725 , A61B5/7267 , A61B5/7275 , A61B5/7405 , A61B5/742 , A61B5/7455 , A61B5/7475 , A61B2562/221 , G06F19/00 , G06K9/0055
摘要： A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk.
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