公开(公告)号：US5191109A

公开(公告)日：1993-03-02

申请号：US648893

申请日：1991-01-31

申请人： Masayoshi Minai ,  Sachiko Imazu ,  Seiichi Kai ,  Takaharu Ikeda ,  Hideyuki Ikehira

发明人： Masayoshi Minai ,  Sachiko Imazu ,  Seiichi Kai ,  Takaharu Ikeda ,  Hideyuki Ikehira

IPC分类号： C07C69/593 ,  C07C69/606 ,  C07C69/738 ,  C07D307/54 ,  C12P7/62 ,  C12P41/00

CPC分类号： C07C69/593 ,  C07C69/606 ,  C07C69/738 ,  C07D307/54 ,  C12P41/004 ,  C12P7/62

摘要： An improved process for preparing an optically active 4-hydroxycyclopentenone of the formula: ##STR1## wherein R is a lower alkyl, the symbol means double bond or triple bond, and the * marked carbon is an asymmetric carbon, and the corresponding racemic 4-hydroxycyclopentenone, which are useful as an intermediate for preparing medicinal or agricultural products, particularly pharmaceutically active prostaglandins, and intermediates for preparing the optically active and/or racemic 4-hydroxycyclopentenone.

摘要翻译： 制备下式的光学活性4-羟基环戊烯酮的改进方法：其中R是低级烷基，符号是指双键或三键，并且*标记的碳是不对称碳，相应的 可用作制备药用或农产品的中间体，特别是药学上可接受的前列腺素的外消旋4-羟基环戊烯酮和用于制备光学活性和/或外消旋4-羟基环戊烯酮的中间体。