专利检索 ap:"Sachiko Oh-ishi" 第 1 页

1.

发明申请
Protein having PGE2 synthase activity and use thereof 审中-公开
标题翻译：具有PGE2合成酶活性的蛋白质及其用途

公开(公告)号：US20070122866A1

公开(公告)日：2007-05-31

申请号：US11648961

申请日：2007-01-03

申请人： Ichiro Kudo , Makoto Murakami , Sachiko Oh-Ishi

发明人： Ichiro Kudo , Makoto Murakami , Sachiko Oh-Ishi

IPC分类号： C12Q1/26 , C07H21/04 , C12P21/06 , C12N9/02 , A61K31/557

CPC分类号： C12N9/90 , A61K38/00

摘要： A single protein which is the substance of the PGE2 synthesis activity in brain soluble fractions of LPS administered rats has been purified and identified. The protein has an activity of synthesizing PGE2 from PGH2, and further, has an activity of synthesizing PGE2 from arachidonic acid in combination with COX.

摘要翻译： 已经纯化并鉴定了作为LPS施用大鼠的脑可溶性级分中PGE2合成活性物质的单一蛋白质。该蛋白质具有从PGH2合成PGE2的活性，并且还具有从花生四烯酸与COX组合合成PGE2的活性。

2.

发明授权
Protein having PGE2 synthase activity and use thereof 失效

公开(公告)号：US07169580B1

公开(公告)日：2007-01-30

申请号：US10182233

申请日：2000-08-25

申请人： Ichiro Kudo , Makoto Murakami , Sachiko Oh-ishi

发明人： Ichiro Kudo , Makoto Murakami , Sachiko Oh-ishi

IPC分类号： C12P31/00 , C12N9/02 , A61K31/19

CPC分类号： C12N9/90 , A61K38/00

摘要： A single protein which is the substance of the PGE2 synthesis activity in brain soluble fractions of LPS administered rats has been purified and identified. The protein has an activity of synthesizing PGE2 from PGH2, and further, has an activity of synthesizing PGE2 from arachidonic acid in combination with COX.