Baculovirus produced plasmodium falciparum vaccine
    2.
    发明授权
    Baculovirus produced plasmodium falciparum vaccine 失效
    杆状病毒产生恶性疟原虫疫苗

    公开(公告)号:US06420523B1

    公开(公告)日:2002-07-16

    申请号:US08195705

    申请日:1994-02-14

    IPC分类号: C07K100

    摘要: The present invention provides compositions of matter comprising a polypeptide expressed from insect cells harboring a baculovirus vector the encodes the polypeptide, wherein the polypeptide comprises amino acid sequences derived from the p42 fragment of the Plasmodium falciparum gp 195 protein or derivatives thereof. Such compositions of matter find use for example for inducing the production of anti-p42 antibodies both in vivo and in vitro.

    摘要翻译: 本发明提供了包含由携带编码多肽的杆状病毒载体的昆虫细胞表达的多肽的物质组合物,其中多肽包含衍生自恶性疟原虫gp1995蛋白质的p42片段的氨基酸序列或其衍生物。 这种物质组合物可用于例如在体内和体外诱导抗p42抗体的产生。