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公开(公告)号:US06500813B1
公开(公告)日:2002-12-31
申请号:US09678256
申请日:2000-10-03
申请人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
发明人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
IPC分类号: A61K3159
CPC分类号: A61K31/593 , A61K31/59 , A61K31/592 , Y10S514/912 , A61K2300/00
摘要: An ophthalmic composition comprises active vitamin D as an effective component and is used for preventing deterioration of the optical transparency, occurrence of high intraocular pressure diseases or defective sight, observed after an ophthalmic operation, due to hyperplasia of the anterior ocular cells in the tissues damaged by the ophthalmic operation, which are in course of a healing process, and/or excess production of cellular materials. The ophthalmic composition can be dropped in the eye after operations such as those for cataract, for transplantation of intraocular lenses and for cornea to maintain the intraocular transparency of the anterior ocular region, to control the hyperplasia of the anterior ocular cells in the tissues damaged by the ophthalmic operation, which are in course of a healing process, and/or excess production of cellular materials and to thus prevent any reduction of visual acuity.
摘要翻译: 一种眼用组合物包含活性维生素D作为有效成分,用于防止眼部手术后观察到的光学透明度降低,高眼内压疾病或视力缺陷,由于组织中前眼细胞的增生受损 通过眼科手术,其处于愈合过程的过程中和/或细胞材料的过量产生。眼科组合物可以在诸如白内障手术,眼内透镜移植和角膜维持等手术后滴入眼中 眼前区域的眼内透明度,以控制由眼科手术损伤的组织中的前眼细胞的增生,其在愈合过程中,和/或细胞材料的过量产生并因此防止任何还原 的视力。
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公开(公告)号:US06187331B1
公开(公告)日:2001-02-13
申请号:US09575987
申请日:2000-05-23
申请人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
发明人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
IPC分类号: A61K3174
CPC分类号: A61K31/59 , A61K9/0048 , A61K31/592 , A61K31/593 , A61K31/74
摘要: An ophthalmic composition for prophylaxis and/or treatment of keratoconjunctivitis sicca, which is locally administered to the eyes and which comprises, as an effective component, at least one member selected from the group consisting of vitamin D, active vitamin D, and active vitamin D analogues.
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公开(公告)号:US5368590A
公开(公告)日:1994-11-29
申请号:US52619
申请日:1993-04-27
申请人: Seiji Itoh
发明人: Seiji Itoh
CPC分类号: A61F13/36 , A61F13/124 , A61F9/0017 , A61F9/00804 , A61F9/009 , A61B2090/3937 , A61F13/12 , A61F2009/00872
摘要: A sponge which is placed on the cornea for laser treatment to absorb unavoidable exuded fluids from the peribulber. This corneal sponge offers protectiveness, convenience and improved effectiveness of corneal laser therapy. The corneal sponge has a surgical space to expose the portion of the cornea to be treated, and is marked for accurate and easy alignment of the microscopic field. The corneal sponge contains a cool ophthalmic solution used to minimize inflammatory response which may cause postoperative complications such as corneal haze and inconsistent corneal refractions.
摘要翻译: 海绵放置在角膜上用于激光治疗以从周围纤维吸收不可避免的渗出液。 角膜海绵提供角膜激光治疗的保护性,方便性和改善的效果。 角膜海绵具有外科空间以暴露要治疗的角膜的部分,并且被标记为准确且容易地对准微观区域。 角膜海绵含有用于最小化炎症反应的凉爽眼用溶液,其可引起术后并发症,例如角膜混浊和不一致的角膜折射。
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公开(公告)号:US5329058A
公开(公告)日:1994-07-12
申请号:US949471
申请日:1992-10-23
申请人: Keizo Shimada , Koji Sumitani , Seiji Itoh , Kazuhiro Sato
发明人: Keizo Shimada , Koji Sumitani , Seiji Itoh , Kazuhiro Sato
IPC分类号: B01J23/04 , B01J27/232 , C07C2/72 , C07C2/58
CPC分类号: B01J27/232 , B01J23/04 , C07C2/72 , C07C2523/04 , C07C2527/232
摘要: In a process for producing an alkenylbenzene by the reaction of an alkylbenzene having 8 or more carbon atoms and a conjugated diolefin, the improvement in which the reaction is performed in the presence of a catalyst obtained by dispersing (a) an alkali metal and (b) potassium carbonate and/or potassium hydroxide in the presence of (c) an aromatic hydrocarbon having at least a substituent with a double bond.
摘要翻译: 在通过具有8个以上碳原子的烷基苯和共轭二烯烃的反应制备烯基苯的方法中,在通过将(a)碱金属和(b)分散而得到的催化剂存在下进行反应的改进 )碳酸钾和/或氢氧化钾在(c)至少具有双键取代基的芳族烃存在下进行。
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公开(公告)号:US20050173026A1
公开(公告)日:2005-08-11
申请号:US10473716
申请日:2002-12-25
申请人: Takao Taniguchi , Kazumasa Tsukamoto , Kouji Ohbayashi , Tomoki Hanyuda , Yutaka Kurebayashi , Hideo Kanisawa , Seiji Itoh
发明人: Takao Taniguchi , Kazumasa Tsukamoto , Kouji Ohbayashi , Tomoki Hanyuda , Yutaka Kurebayashi , Hideo Kanisawa , Seiji Itoh
摘要: A carburizing and hardening method enhances strength while sufficiently reducing hardening strain, without increasing the production cost, and a carburized and hardened member produced thereby. The raw material is an alloy steel which contains Fe as a main component, 0.10 to 0.50 wt. % C and 0.50 to 1.50 wt. % Si and having a hardenability J, based on an end quenching test, in a range of 35 to 50 (at 12.5 mm). After the raw material is formed into the desired shape, a carburized layer is formed by carburizing in an oxidation inhibiting atmosphere. After the carburizing, quenching is performed with cooling, uninterrupted by temperature rise, from a pearlite transformation point (A1 point) to a martensite transformation start point (Ms point), and with a severity of quenching H in a range of 0.01 to 0.08 (cm−1).
摘要翻译: 渗碳硬化方法提高强度,同时充分降低硬化应变,而不增加生产成本,并且由此生产的渗碳硬化构件。 原料是含有Fe作为主要成分的合金钢,0.10〜0.50重量% %C和0.50〜1.50wt。 %Si,并且基于终止淬火试验具有淬透性J,在35〜50(12.5mm)的范围内。 在原料形成所需形状之后,通过在氧化抑制气氛中渗碳形成渗碳层。 渗碳后,从珠光体相变点(A1点)到马氏体相变开始点(Ms点)的冷却不间断地进行淬火淬火,淬火强度H在0.01〜0.08的范围内( cm -1)。
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公开(公告)号:US06410006B1
公开(公告)日:2002-06-25
申请号:US09784147
申请日:2001-02-16
申请人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
发明人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
IPC分类号: A61K3174
摘要: An ophthalmic composition for prophylaxis and/or treatment of keratoconjunctivitis sicca, which is locally administered to the eyes and which comprises, as an effective component, at least one member selected from the group consisting of vitamin D, active vitamin D, and active vitamin D analogues.
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公开(公告)号:US5876709A
公开(公告)日:1999-03-02
申请号:US863425
申请日:1997-05-27
申请人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
发明人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai , Kiyoshi Kita
IPC分类号: A61K9/00 , A61K31/122 , A61K31/59 , A61K31/592 , A61K31/593 , A61K45/06 , A61P27/02 , A61P37/08 , H01R39/38 , H02K5/14 , H02K13/00 , A61K9/127 , A61K9/14 , A61K31/74
CPC分类号: A61K9/0048 , A61K31/122 , A61K31/59 , A61K31/592 , A61K31/593 , A61K45/06 , Y10S514/912
摘要: An ophthalmic composition for preventing corneal haze and corneal refraction anomaly observed after anterior ocular tissues are damaged or during corneal diseases comprises, as an effective component, vitamin D such as ergocalciferols and cholecalciferols or active vitamin D.
摘要翻译: 用于预防眼前组织损伤或角膜疾病之后观察到的角膜雾霾和角膜屈光异常的眼用组合物包含作为有效成分的维生素D如麦角钙化醇和胆钙化醇或活性维生素D.
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公开(公告)号:US5290906A
公开(公告)日:1994-03-01
申请号:US644978
申请日:1991-01-23
申请人: Shunichi Matsumura , Seiji Itoh , Hiroo Inata , Jiro Sadanobu
发明人: Shunichi Matsumura , Seiji Itoh , Hiroo Inata , Jiro Sadanobu
CPC分类号: C08J5/18 , C08G65/4012 , D01F6/665 , C08J2371/00 , Y10T428/29 , Y10T428/2913 , Y10T428/2967 , Y10T428/31504
摘要: A poly(arylene ether ketone) of this invention principally comprises recurring units represented by formula ##STR1## wherein Ar.sup.1 denotes a 1,5-naphthalene ring, a 2,6-naphthalene ring, a 2,7-naphthalene ring or a combination of them, and Ar.sup.2 denotes p-phenylene, p,p'-biphenylene, a 1,5-naphthalene ring, a 2,6-naphthalene ring, a 2,7-naphthalene ring or a combination of them.The poly(arylene ether ketone) is high in second-order transition temperature and excellent in solvent resistance and moldability, and can be molded into heat-resistant fibers and electric insulating films.
摘要翻译: 本发明的聚(亚芳基醚酮)主要包含由式(*化学结构*)表示的重复单元,其中Ar 1表示1,5-萘环,2,6-萘环,2,7-萘环或 它们的组合,Ar 2表示对亚苯基,p,p'-联苯,1,5-萘环,2,6-萘环,2,7-萘环或它们的组合。 聚(亚芳基醚酮)二级转变温度高,耐溶剂性和成型性优异,可以成型为耐热纤维和电绝缘膜。
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公开(公告)号:US4582447A
公开(公告)日:1986-04-15
申请号:US506039
申请日:1983-06-20
申请人: Seiji Itoh
发明人: Seiji Itoh
CPC分类号: A63H33/108 , Y10S206/821 , Y10S24/38 , Y10T24/45262 , Y10T403/57 , Y10T403/5733 , Y10T403/65 , Y10T403/7039
摘要: An adaptor structure for connecting a plurality of beverage cans together in selected configurations comprising a base plate with connector members on a first side thereof, a can-receiving socket on the opposite side thereof and spacer members within said socket. The cans have end recesses in which the spacer members seat when an adaptor is coupled to a can to form a strong, stable connection. Cans are assembled end-to-end with back-to-back adaptors at the end interfaces, the adaptors being connected to each other by the connector members.
摘要翻译: 一种用于将多个饮料罐连接在一起的适配器结构,其选择的配置包括在其第一侧上具有连接器构件的基板,在其相对侧上的可容纳插座和位于所述插座内的隔离构件。 罐具有端部凹槽,当适配器联接到罐体上时,间隔件构件就位于其中,以形成牢固且稳定的连接。 罐在端部接口处以背对背适配器端对端组装,适配器通过连接器构件相互连接。
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公开(公告)号:US06248732B1
公开(公告)日:2001-06-19
申请号:US08913522
申请日:1997-11-24
申请人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai
发明人: Seiji Itoh , Yasuo Ishii , Katsuhiko Mukai
IPC分类号: A61K3159
CPC分类号: A61K31/593 , A61K31/59 , A61K31/592 , Y10S514/912 , A61K2300/00
摘要: An ophthalmic composition comprises active vitamin D as an effective component and is used for preventing deterioration of the optical transparency, occurrence of high intraocular pressure diseases or defective sight, observed after an ophthalmic operation, due to hyperplasia of the anterior ocular cells in the tissues damaged by the ophthalmic operation, which are in course of a healing process, and/or excess production of cellular materials. The ophthalmic composition can be dropped in the eye after operations such as those for cataract, for transplantation of intraocular lenses and for cornea to maintain the intraocular transparency of the anterior ocular region, to control the hyperplasia of the anterior ocular cells in the tissues damaged by the ophthalmic operation, which are in course of a healing process, and/or excess production of cellular materials and to thus prevent any reduction of visual acuity.
摘要翻译: 一种眼用组合物包含活性维生素D作为有效成分,用于防止眼部手术后观察到的光学透明度降低,高眼内压疾病或视力缺陷,由于组织中前眼细胞的增生受损 通过眼科手术,其处于愈合过程的过程中和/或细胞材料的过量产生。眼科组合物可以在诸如白内障手术,眼内透镜移植和角膜维持等手术后滴入眼中 眼前区域的眼内透明度,以控制由眼科手术损伤的组织中的前眼细胞的增生,其在愈合过程中,和/或细胞材料的过量产生并因此防止任何还原 的视力。
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